SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mv9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IKE_A_HSMA190_1
(NITROPHORIN 4)		 5mv9 UNCONVENTIONAL
MYOSIN-VIIA
(Homo
sapiens) 		3 / 3 ASP A1811
LEU A1851
LEU A1850
 None
 0.68A 1ikeA-5mv9A:
undetectable		 1ikeA-5mv9A:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1870_0
(FPRA)		 5mv9 UNCONVENTIONAL
MYOSIN-VIIA
(Homo
sapiens) 		4 / 4 HIS A2152
PRO A2153
LYS A2156
ILE A2157
 None
 1.29A 1lqtA-5mv9A:
undetectable		 1lqtA-5mv9A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NP1_B_HSMB304_1
(NITROPHORIN 1)		 5mv9 UNCONVENTIONAL
MYOSIN-VIIA
(Homo
sapiens) 		3 / 3 ASP A1811
LEU A1851
LEU A1850
 None
 0.72A 1np1B-5mv9A:
undetectable		 1np1B-5mv9A:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W76_A_GNTA1538_1
(ACETYLCHOLINESTERASE)		 5mv9 UNCONVENTIONAL
MYOSIN-VIIA
(Homo
sapiens) 		5 / 11 TRP A1838
GLY A1842
GLU A1891
PHE A1844
PHE A1800
 None
 1.41A 1w76A-5mv9A:
undetectable		 1w76A-5mv9A:
24.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HC4_A_VDXA525_2
(VITAMIN D RECEPTOR)		 5mv9 UNCONVENTIONAL
MYOSIN-VIIA
(Homo
sapiens) 		4 / 7 LEU A1858
ARG A1832
SER A1829
TYR A1814
 None
 1.19A 2hc4A-5mv9A:
undetectable		 2hc4A-5mv9A:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_3
(PHOSPHOLIPASE A2)		 5mv9 UNCONVENTIONAL
MYOSIN-VIIA
(Homo
sapiens) 		3 / 3 PRO A1846
PHE A1800
LYS A1810
 None
 1.11A 3bjwG-5mv9A:
undetectable		 3bjwG-5mv9A:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR4_X_PNTX101_0
(PROTEIN S100-B)		 5mv9 UNCONVENTIONAL
MYOSIN-VIIA
(Homo
sapiens) 		3 / 3 CYH A2182
HIS A2168
PHE A2167
 None
 1.06A 3cr4X-5mv9A:
undetectable		 3cr4X-5mv9A:
11.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_E_TOPE200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 5mv9 UNCONVENTIONAL
MYOSIN-VIIA
(Homo
sapiens) 		5 / 10 LEU A2140
ILE A2133
LEU A2194
PHE A2167
THR A2121
 None
 1.12A 3fl9E-5mv9A:
undetectable		 3fl9E-5mv9A:
15.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_2
(GENOME POLYPROTEIN)		 5mv9 UNCONVENTIONAL
MYOSIN-VIIA
(Homo
sapiens) 		4 / 4 PHE A2085
TYR A2052
VAL A2034
LEU A2037
 None
 1.44A 3keeD-5mv9A:
undetectable		 3keeD-5mv9A:
16.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R0L_D_ACTD127_0
(PHOSPHOLIPASE A2 CB)		 5mv9 UNCONVENTIONAL
MYOSIN-VIIA
(Homo
sapiens) 		4 / 5 PHE A2114
ILE A2141
GLY A2025
HIS A2027
 None
 1.38A 3r0lD-5mv9A:
undetectable		 3r0lD-5mv9A:
10.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_0
(PUTATIVE REGULATORY
PROTEIN)		 5mv9 UNCONVENTIONAL
MYOSIN-VIIA
(Homo
sapiens) 		5 / 12 LEU A2130
TYR A2026
CYH A2029
VAL A2034
ASP A2067
 None
 1.13A 3vw1D-5mv9A:
1.1		 3vw1D-5mv9A:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_F_AM2F301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5mv9 UNCONVENTIONAL
MYOSIN-VIIA
(Homo
sapiens) 		4 / 7 ARG A1967
HIS A1968
GLU A1801
ASP A1797
 None
 1.31A 6mn4F-5mv9A:
undetectable		 6mn4F-5mv9A:
18.79