SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mvh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_A_RBFA98_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 5mvh BACCELL_00856
(Bacteroides
cellulosilyticus) 		5 / 10 LEU A 103
LEU A 125
THR A  80
PHE A 146
ILE A  93
 None
 1.39A 1i18A-5mvhA:
undetectable
1i18B-5mvhA:
undetectable		 1i18A-5mvhA:
11.06
1i18B-5mvhA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I18_B_RBFB99_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 5mvh BACCELL_00856
(Bacteroides
cellulosilyticus) 		5 / 10 PHE A 146
ILE A  93
LEU A 103
LEU A 125
THR A  80
 None
 1.42A 1i18A-5mvhA:
undetectable
1i18B-5mvhA:
undetectable		 1i18A-5mvhA:
11.06
1i18B-5mvhA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_A_DVAA6_0
(GRAMICIDIN A)		 5mvh BACCELL_00856
(Bacteroides
cellulosilyticus) 		3 / 3 ALA A 362
VAL A 364
TRP A 369
 None
 0.63A 1nt5A-5mvhA:
undetectable		 1nt5A-5mvhA:
2.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_B_DVAB6_0
(GRAMICIDIN A)		 5mvh BACCELL_00856
(Bacteroides
cellulosilyticus) 		3 / 3 ALA A 362
VAL A 364
TRP A 369
 None
 0.63A 1nt5B-5mvhA:
undetectable		 1nt5B-5mvhA:
2.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_1
(SUN PROTEIN)		 5mvh BACCELL_00856
(Bacteroides
cellulosilyticus) 		3 / 3 PRO A 281
ASP A 276
ASP A 303
 None
 0.73A 1sqfA-5mvhA:
undetectable		 1sqfA-5mvhA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VM1_A_TAZA504_1
(BETA-LACTAMASE SHV-1)		 5mvh BACCELL_00856
(Bacteroides
cellulosilyticus) 		3 / 3 ASP A 153
TYR A 173
GLU A 100
 None
 0.86A 1vm1A-5mvhA:
undetectable		 1vm1A-5mvhA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA471_1
(CYTOCHROME P450 51)		 5mvh BACCELL_00856
(Bacteroides
cellulosilyticus) 		4 / 8 TYR A 197
PHE A  40
ARG A 333
HIS A 110
 None
 1.08A 1x8vA-5mvhA:
undetectable		 1x8vA-5mvhA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA6_0
(GRAMICIDIN D)		 5mvh BACCELL_00856
(Bacteroides
cellulosilyticus) 		3 / 3 ALA A 275
VAL A 337
TRP A 391
 None
 0.93A 2izqA-5mvhA:
undetectable
2izqB-5mvhA:
undetectable		 2izqA-5mvhA:
3.00
2izqB-5mvhA:
3.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 5mvh BACCELL_00856
(Bacteroides
cellulosilyticus) 		3 / 3 ASN A 309
ARG A 298
ASP A 291
 None
 0.99A 2qe6A-5mvhA:
undetectable		 2qe6A-5mvhA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 5mvh BACCELL_00856
(Bacteroides
cellulosilyticus) 		3 / 3 ASN A 309
ARG A 298
ASP A 291
 None
 1.00A 2qe6B-5mvhA:
undetectable		 2qe6B-5mvhA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_1
(UNCHARACTERIZED
PROTEIN RPA2492)		 5mvh BACCELL_00856
(Bacteroides
cellulosilyticus) 		3 / 3 TYR A 232
ASP A 203
HIS A 302
 None
 0.87A 3e23A-5mvhA:
undetectable		 3e23A-5mvhA:
19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_B_H3PB552_1
(GLUTAMATE
DEHYDROGENASE)		 5mvh BACCELL_00856
(Bacteroides
cellulosilyticus) 		3 / 3 TYR A 257
TYR A 246
ILE A 250
 None
 0.82A 3eteA-5mvhA:
undetectable
3eteB-5mvhA:
undetectable		 3eteA-5mvhA:
18.85
3eteB-5mvhA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R24_A_SAMA302_1
(2'-O-METHYL
TRANSFERASE)		 5mvh BACCELL_00856
(Bacteroides
cellulosilyticus) 		3 / 3 TYR A 297
ASP A 373
ASP A 349
 None
 0.84A 3r24A-5mvhA:
undetectable		 3r24A-5mvhA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U8Q_A_NPUA7231_1
(LACTOTRANSFERRIN)		 5mvh BACCELL_00856
(Bacteroides
cellulosilyticus) 		4 / 5 GLY A 279
PRO A 281
ASN A 280
TYR A 282
 None
 1.26A 3u8qA-5mvhA:
undetectable		 3u8qA-5mvhA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZS3_A_ACTA1227_0
(THAUMATIN-LIKE
PROTEIN)		 5mvh BACCELL_00856
(Bacteroides
cellulosilyticus) 		4 / 4 THR A 271
ARG A 333
ASN A 223
ILE A 268
 None
 1.39A 3zs3A-5mvhA:
0.0		 3zs3A-5mvhA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EYS_A_ACTA402_0
(MCCC FAMILY PROTEIN)		 5mvh BACCELL_00856
(Bacteroides
cellulosilyticus) 		4 / 6 SER A 274
ASP A 339
ARG A 395
GLU A 204
 None
 0.95A 4eysA-5mvhA:
undetectable		 4eysA-5mvhA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 5mvh BACCELL_00856
(Bacteroides
cellulosilyticus) 		3 / 3 GLY A 152
ASP A 153
ASN A 181
 None
 0.56A 5jglA-5mvhA:
undetectable		 5jglA-5mvhA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_E_ASCE1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 5mvh BACCELL_00856
(Bacteroides
cellulosilyticus) 		4 / 7 HIS A  90
ILE A  92
VAL A  35
TYR A  57
 None
 1.12A 5kkzC-5mvhA:
1.0
5kkzE-5mvhA:
undetectable		 5kkzC-5mvhA:
16.40
5kkzE-5mvhA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_K_ASCK1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 5mvh BACCELL_00856
(Bacteroides
cellulosilyticus) 		4 / 7 HIS A  90
ILE A  92
VAL A  35
TYR A  57
 None
 1.13A 5kkzK-5mvhA:
undetectable
5kkzQ-5mvhA:
undetectable		 5kkzK-5mvhA:
21.46
5kkzQ-5mvhA:
16.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_O_ASCO1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)		 5mvh BACCELL_00856
(Bacteroides
cellulosilyticus) 		4 / 7 HIS A  90
ILE A  92
VAL A  35
TYR A  57
 None
 1.11A 5kkzM-5mvhA:
undetectable
5kkzO-5mvhA:
undetectable		 5kkzM-5mvhA:
16.40
5kkzO-5mvhA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7B_B_PA1B204_1
(ACYLOXYACYL
HYDROLASE SMALL
SUBUNIT
ACYLOXYACYL
HYDROLASE LARGE
SUBUNIT)		 5mvh BACCELL_00856
(Bacteroides
cellulosilyticus) 		3 / 3 GLY A 304
ASN A 280
ARG A 230
 None
 0.79A 5w7bD-5mvhA:
undetectable		 5w7bD-5mvhA:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_ACTA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 5mvh BACCELL_00856
(Bacteroides
cellulosilyticus) 		3 / 3 GLN A  52
TRP A  75
VAL A  24
 None
 1.11A 6auuA-5mvhA:
undetectable		 6auuA-5mvhA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HXI_B_ACTB706_0
(SUCCINYL-COA LIGASE
(ADP-FORMING)
SUBUNIT ALPHA)		 5mvh BACCELL_00856
(Bacteroides
cellulosilyticus) 		4 / 5 HIS A 398
VAL A 422
ARG A 396
ARG A  68
 None
 1.35A 6hxiB-5mvhA:
undetectable		 6hxiB-5mvhA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_1
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 5mvh BACCELL_00856
(Bacteroides
cellulosilyticus) 		3 / 3 ASP A 185
SER A 162
SER A 160
 None
 0.78A 6mxtA-5mvhA:
undetectable		 6mxtA-5mvhA:
20.25