SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mvo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5mvo FOXE
(Rhodobacter
sp.
SW2) 		4 / 5 ARG A  93
ASP A 228
MET A 230
ASN A 123
 HEC  A 301 (-3.8A)
None
HEC  A 301 (-2.2A)
None
 1.43A 1nbiA-5mvoA:
undetectable		 1nbiA-5mvoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_B_SAMB1293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5mvo FOXE
(Rhodobacter
sp.
SW2) 		4 / 5 ARG A  93
ASP A 228
MET A 230
ASN A 123
 HEC  A 301 (-3.8A)
None
HEC  A 301 (-2.2A)
None
 1.43A 1nbiB-5mvoA:
undetectable		 1nbiB-5mvoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1303_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5mvo FOXE
(Rhodobacter
sp.
SW2) 		5 / 7 PRO A 125
SER A 128
ILE A 131
PRO A 164
GLY A 163
 None
 1.28A 2y7kA-5mvoA:
undetectable		 2y7kA-5mvoA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_A_SAMA500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 5mvo FOXE
(Rhodobacter
sp.
SW2) 		3 / 3 HIS A 242
SER A 237
GLU A 238
 None
 0.92A 3s8pA-5mvoA:
undetectable		 3s8pA-5mvoA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 5mvo FOXE
(Rhodobacter
sp.
SW2) 		4 / 4 GLY A  82
LEU A 248
PHE A 249
ILE A 107
 None
 0.78A 4xv2A-5mvoA:
undetectable		 4xv2A-5mvoA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_2
(SIALIDASE)		 5mvo FOXE
(Rhodobacter
sp.
SW2) 		4 / 6 ASP A 239
GLN A 246
LEU A  32
SER A  28
 None
 1.26A 6ekuA-5mvoA:
undetectable		 6ekuA-5mvoA:
8.27