SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mvx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2JJP_A_KLNA413_1 (CYTOCHROME P450 113A1)	5mvx	DELTA-LIKE PROTEIN 4 (Homo sapiens)	5 / 12	ALA A 45 LEU A 139 THR A 56 GLN A 160 ILE A 119	None	1.20A	2jjpA-5mvxA: undetectable	2jjpA-5mvxA: 18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O2B_B_LOCB503_1 (TUBULIN ALPHA-1B CHAIN TUBULIN BETA-2B CHAIN)	5mvx	DELTA-LIKE PROTEIN 4 (Homo sapiens)	3 / 3	SER A 88 ALA A 90 VAL A 91	None	0.63A	4o2bA-5mvxA: undetectable	4o2bA-5mvxA: 21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B89_B_NOVB403_1 (LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB)	5mvx	DELTA-LIKE PROTEIN 4 (Homo sapiens)	4 / 7	PHE A 37 ARG A 166 ARG A 168 ALA A 121	None	1.31A	6b89A-5mvxA: undetectable	6b89A-5mvxA: 14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B89_B_NOVB403_1 (LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB)	5mvx	DELTA-LIKE PROTEIN 4 (Homo sapiens)	4 / 7	PHE A 37 ARG A 168 LEU A 167 ALA A 121	None	1.11A	6b89A-5mvxA: undetectable	6b89A-5mvxA: 14.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NMP_P_CHDP307_0 (CYTOCHROME C OXIDASE SUBUNIT 3 CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5mvx	DELTA-LIKE PROTEIN 4 (Homo sapiens)	4 / 5	LEU A 103 GLN A 31 PHE A 30 PHE A 58	None	1.31A	6nmpP-5mvxA: undetectable 6nmpW-5mvxA: undetectable	6nmpP-5mvxA: 19.64 6nmpW-5mvxA: 10.70

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2JJP_A_KLNA413_1","CYTOCHROME P450 113A1","5mvx","DELTA-LIKE PROTEIN 4","Homo sapiens",5,"ALA A  45;LEU A 139;THR A  56;GLN A 160;ILE A 119","None","1.20A","2jjpA-5mvxA:undetectable","2jjpA-5mvxA:18.51"],["4O2B_B_LOCB503_1","TUBULIN ALPHA-1B CHAIN;TUBULIN BETA-2B CHAIN","5mvx","DELTA-LIKE PROTEIN 4","Homo sapiens",3,"SER A  88;ALA A  90;VAL A  91","None","0.63A","4o2bA-5mvxA:undetectable","4o2bA-5mvxA:21.86"],["6B89_B_NOVB403_1","LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB;LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB","5mvx","DELTA-LIKE PROTEIN 4","Homo sapiens",4,"PHE A  37;ARG A 166;ARG A 168;ALA A 121","None","1.31A","6b89A-5mvxA:undetectable","6b89A-5mvxA:14.06"],["6B89_B_NOVB403_1","LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB;LIPOPOLYSACCHARIDE EXPORT SYSTEM ATP-BINDING PROTEIN LPTB","5mvx","DELTA-LIKE PROTEIN 4","Homo sapiens",4,"PHE A  37;ARG A 168;LEU A 167;ALA A 121","None","1.11A","6b89A-5mvxA:undetectable","6b89A-5mvxA:14.06"],["6NMP_P_CHDP307_0","CYTOCHROME C OXIDASE SUBUNIT 3;CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5mvx","DELTA-LIKE PROTEIN 4","Homo sapiens",4,"LEU A 103;GLN A  31;PHE A  30;PHE A  58","None","1.31A","6nmpP-5mvxA:undetectable;6nmpW-5mvxA:undetectable","6nmpP-5mvxA:19.64;6nmpW-5mvxA:10.70"]]