SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mw7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_A_BEZA1162_0
(PEROXIREDOXIN 5)		 5mw7 PROTEIN JAGGED-2
(Homo
sapiens) 		5 / 10 THR A  95
PRO A  96
LEU A  37
THR A  69
GLY A  99
 None
 1.28A 1h4oA-5mw7A:
undetectable
1h4oB-5mw7A:
undetectable		 1h4oA-5mw7A:
18.15
1h4oB-5mw7A:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2MJI_A_KTRA201_1
(FATTY ACID-BINDING
PROTEIN, INTESTINAL)		 5mw7 PROTEIN JAGGED-2
(Homo
sapiens) 		5 / 12 ILE A 163
THR A  95
LEU A  98
PHE A 103
LEU A 105
 None
 1.43A 2mjiA-5mw7A:
undetectable		 2mjiA-5mw7A:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PH9_A_GNTA301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5mw7 PROTEIN JAGGED-2
(Homo
sapiens) 		4 / 7 TYR A  90
TRP A 138
GLN A  79
ILE A 172
 None
 1.28A 2ph9A-5mw7A:
undetectable
2ph9B-5mw7A:
undetectable		 2ph9A-5mw7A:
19.65
2ph9B-5mw7A:
19.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A6I_A_TCWA1124_1
(TRANSTHYRETIN)		 5mw7 PROTEIN JAGGED-2
(Homo
sapiens) 		4 / 6 LYS A 179
LEU A 181
LEU A 192
VAL A 196
 None
 0.84A 5a6iA-5mw7A:
3.0		 5a6iA-5mw7A:
18.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPL_B_PA1B605_1
(LIPID A EXPORT
ATP-BINDING/PERMEASE
PROTEIN MSBA)		 5mw7 PROTEIN JAGGED-2
(Homo
sapiens) 		3 / 3 ARG A 195
ARG A 116
ARG A 114
 None
 1.10A 6bplA-5mw7A:
undetectable
6bplB-5mw7A:
undetectable		 6bplA-5mw7A:
12.97
6bplB-5mw7A:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_Q_PCFQ202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5mw7 PROTEIN JAGGED-2
(Homo
sapiens) 		4 / 6 TYR A  29
ALA A 115
ARG A 114
ASP A 176
 None
 1.00A 6hu9m-5mw7A:
undetectable
6hu9q-5mw7A:
undetectable		 6hu9m-5mw7A:
18.72
6hu9q-5mw7A:
16.87