SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mwb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YN6_A_SAMA401_0
(NSP16 PROTEIN)		 5mwb NEUROGENIC LOCUS
NOTCH HOMOLOG
PROTEIN 2
(Homo
sapiens) 		5 / 12 GLY A 507
PRO A 527
GLY A 526
ASN A 506
ASN A 501
 None
 1.33A 5yn6A-5mwbA:
undetectable		 5yn6A-5mwbA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNI_A_SAMA401_0
(NSP16 PROTEIN)		 5mwb NEUROGENIC LOCUS
NOTCH HOMOLOG
PROTEIN 2
(Homo
sapiens) 		5 / 12 GLY A 507
PRO A 527
GLY A 526
ASN A 506
ASN A 501
 None
 1.33A 5yniA-5mwbA:
undetectable		 5yniA-5mwbA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YNM_A_SAMA401_0
(NSP16 PROTEIN)		 5mwb NEUROGENIC LOCUS
NOTCH HOMOLOG
PROTEIN 2
(Homo
sapiens) 		5 / 12 GLY A 507
PRO A 527
GLY A 526
ASN A 506
ASN A 501
 None
 1.33A 5ynmA-5mwbA:
undetectable		 5ynmA-5mwbA:
18.75