SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mwl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		5 / 11 ALA A 196
LEU A 197
LEU A 185
LEU A 319
ILE A 403
 None
 1.03A 1ha2A-5mwlA:
undetectable		 1ha2A-5mwlA:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Z_A_COCA301_2
(CHIMERA OF IG KAPPA
CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION
CHIMERA OF IG
GAMMA-1 CHAIN: HUMAN
CONSTANT REGION AND
MOUSE VARIABLE
REGION)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		4 / 5 TYR A 337
GLU A 334
TYR A 450
ASP A 453
 None
 1.14A 1i7zB-5mwlA:
undetectable		 1i7zB-5mwlA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		5 / 6 LEU A 452
TYR A 392
ARG A 393
MET A 396
THR A 397
 5MY  A 502 (-4.6A)
None
None
None
None
 1.16A 1v54A-5mwlA:
undetectable
1v54J-5mwlA:
undetectable		 1v54A-5mwlA:
19.60
1v54J-5mwlA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		5 / 6 LEU A 452
TYR A 392
ARG A 393
MET A 396
THR A 397
 5MY  A 502 (-4.6A)
None
None
None
None
 1.15A 2dyrA-5mwlA:
undetectable
2dyrJ-5mwlA:
undetectable		 2dyrA-5mwlA:
19.60
2dyrJ-5mwlA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_J_CHDJ101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		5 / 6 LEU A 452
TYR A 392
ARG A 393
MET A 396
THR A 397
 5MY  A 502 (-4.6A)
None
None
None
None
 1.19A 2dysA-5mwlA:
undetectable
2dysJ-5mwlA:
undetectable		 2dysA-5mwlA:
19.60
2dysJ-5mwlA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_W_CHDW101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		5 / 6 LEU A 452
TYR A 392
ARG A 393
MET A 396
THR A 397
 5MY  A 502 (-4.6A)
None
None
None
None
 1.22A 2dysN-5mwlA:
undetectable
2dysW-5mwlA:
undetectable		 2dysN-5mwlA:
19.60
2dysW-5mwlA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		5 / 6 LEU A 452
TYR A 392
ARG A 393
MET A 396
THR A 397
 5MY  A 502 (-4.6A)
None
None
None
None
 1.21A 2eijA-5mwlA:
undetectable
2eijJ-5mwlA:
undetectable		 2eijA-5mwlA:
19.60
2eijJ-5mwlA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		5 / 6 LEU A 452
TYR A 392
ARG A 393
MET A 396
THR A 397
 5MY  A 502 (-4.6A)
None
None
None
None
 1.18A 2eilA-5mwlA:
undetectable
2eilJ-5mwlA:
undetectable		 2eilA-5mwlA:
19.60
2eilJ-5mwlA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		4 / 5 TYR A 392
ARG A 393
MET A 396
THR A 397
 None
 0.95A 2eimJ-5mwlA:
undetectable		 2eimJ-5mwlA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		4 / 5 TYR A 392
ARG A 393
MET A 396
THR A 397
 None
 0.96A 2eimW-5mwlA:
undetectable		 2eimW-5mwlA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		4 / 6 TYR A 392
ARG A 393
MET A 396
THR A 397
 None
 0.83A 2einN-5mwlA:
undetectable
2einW-5mwlA:
undetectable		 2einN-5mwlA:
19.60
2einW-5mwlA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GJ5_A_VD3A163_1
(BETA-LACTOGLOBULIN)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		5 / 12 LEU A 270
VAL A 433
ILE A 403
ILE A 137
ALA A 196
 None
 1.13A 2gj5A-5mwlA:
undetectable		 2gj5A-5mwlA:
15.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H42_C_VIAC903_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		5 / 12 LEU A 233
ILE A 217
ALA A 406
LEU A 429
ILE A 132
 None
 1.03A 2h42C-5mwlA:
undetectable		 2h42C-5mwlA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		5 / 6 LEU A 452
TYR A 392
ARG A 393
MET A 396
THR A 397
 5MY  A 502 (-4.6A)
None
None
None
None
 1.15A 2zxwA-5mwlA:
undetectable
2zxwJ-5mwlA:
undetectable		 2zxwA-5mwlA:
19.60
2zxwJ-5mwlA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		4 / 7 LEU A 452
TYR A 392
ARG A 393
THR A 397
 5MY  A 502 (-4.6A)
None
None
None
 1.16A 2zxwN-5mwlA:
undetectable
2zxwW-5mwlA:
undetectable		 2zxwN-5mwlA:
19.60
2zxwW-5mwlA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		4 / 5 TYR A 392
ARG A 393
MET A 396
THR A 397
 None
 0.95A 3abkN-5mwlA:
undetectable
3abkW-5mwlA:
undetectable		 3abkN-5mwlA:
19.60
3abkW-5mwlA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		5 / 6 LEU A 452
TYR A 392
ARG A 393
MET A 396
THR A 397
 5MY  A 502 (-4.6A)
None
None
None
None
 1.13A 3abmA-5mwlA:
undetectable
3abmJ-5mwlA:
undetectable		 3abmA-5mwlA:
19.60
3abmJ-5mwlA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		4 / 5 TYR A 392
ARG A 393
MET A 396
THR A 397
 None
 0.69A 3ag1J-5mwlA:
undetectable		 3ag1J-5mwlA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		4 / 6 TYR A 392
ARG A 393
MET A 396
THR A 397
 None
 0.78A 3ag1N-5mwlA:
undetectable
3ag1W-5mwlA:
undetectable		 3ag1N-5mwlA:
19.60
3ag1W-5mwlA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		4 / 5 TYR A 392
ARG A 393
MET A 396
THR A 397
 None
 1.01A 3ag2J-5mwlA:
undetectable		 3ag2J-5mwlA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		5 / 7 LEU A 452
TYR A 392
ARG A 393
MET A 396
THR A 397
 5MY  A 502 (-4.6A)
None
None
None
None
 1.32A 3ag2N-5mwlA:
undetectable
3ag2W-5mwlA:
undetectable		 3ag2N-5mwlA:
19.60
3ag2W-5mwlA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		4 / 5 TYR A 392
ARG A 393
MET A 396
THR A 397
 None
 0.95A 3ag4J-5mwlA:
undetectable		 3ag4J-5mwlA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		5 / 7 LEU A 452
TYR A 392
ARG A 393
MET A 396
THR A 397
 5MY  A 502 (-4.6A)
None
None
None
None
 1.24A 3ag4N-5mwlA:
undetectable
3ag4W-5mwlA:
undetectable		 3ag4N-5mwlA:
19.60
3ag4W-5mwlA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		5 / 6 LEU A 452
TYR A 392
ARG A 393
MET A 396
THR A 397
 5MY  A 502 (-4.6A)
None
None
None
None
 1.19A 3asnA-5mwlA:
undetectable
3asnJ-5mwlA:
undetectable		 3asnA-5mwlA:
19.60
3asnJ-5mwlA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		5 / 6 LEU A 452
TYR A 392
ARG A 393
MET A 396
THR A 397
 5MY  A 502 (-4.6A)
None
None
None
None
 1.19A 3asoA-5mwlA:
undetectable
3asoJ-5mwlA:
undetectable		 3asoA-5mwlA:
19.60
3asoJ-5mwlA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G8I_A_RO7A1_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR ALPHA)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		4 / 7 LEU A 185
LEU A 237
VAL A 262
LEU A 208
 None
 0.94A 3g8iA-5mwlA:
undetectable		 3g8iA-5mwlA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_1
(STRUCTURAL PROTEIN
VP3)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		3 / 3 GLU A 365
ASP A  65
ASP A  57
 None
 0.62A 3jb2A-5mwlA:
undetectable		 3jb2A-5mwlA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		4 / 6 LEU A 452
TYR A 392
MET A 396
THR A 397
 5MY  A 502 (-4.6A)
None
None
None
 1.08A 3wg7A-5mwlA:
undetectable
3wg7J-5mwlA:
undetectable		 3wg7A-5mwlA:
19.60
3wg7J-5mwlA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_F_ACTF402_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		3 / 3 PHE A  58
ASP A 360
ARG A 393
 None
 0.74A 4eahF-5mwlA:
undetectable		 4eahF-5mwlA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_G_ACTG401_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		3 / 3 PHE A  58
ASP A 360
ARG A 393
 None
 0.74A 4eahG-5mwlA:
undetectable		 4eahG-5mwlA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_A_RTZA602_1
(CYTOCHROME P450 2D6)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		5 / 12 PHE A  58
GLY A  68
LEU A  67
VAL A 435
VAL A 394
 None
 1.14A 4wnwA-5mwlA:
0.4		 4wnwA-5mwlA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		4 / 7 TYR A 392
ARG A 393
MET A 396
THR A 397
 None
 0.83A 5iy5N-5mwlA:
undetectable
5iy5W-5mwlA:
undetectable		 5iy5N-5mwlA:
19.60
5iy5W-5mwlA:
9.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KM8_B_L8PB201_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 2,
MITOCHONDRIAL)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		4 / 8 GLN A 412
ALA A 430
SER A 432
HIS A 129
 None
None
None
ZN  A 504 (-3.5A)
 1.19A 5km8A-5mwlA:
undetectable
5km8B-5mwlA:
undetectable		 5km8A-5mwlA:
13.66
5km8B-5mwlA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		4 / 5 TYR A 392
ARG A 393
MET A 396
THR A 397
 None
 0.82A 5w97J-5mwlA:
undetectable		 5w97J-5mwlA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		4 / 5 TYR A 392
ARG A 393
MET A 396
THR A 397
 None
 0.79A 5wauJ-5mwlA:
undetectable		 5wauJ-5mwlA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		4 / 5 TYR A 392
ARG A 393
MET A 396
THR A 397
 None
 0.90A 5x1bW-5mwlA:
undetectable		 5x1bW-5mwlA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		5 / 6 LEU A 452
TYR A 392
ARG A 393
MET A 396
THR A 397
 5MY  A 502 (-4.6A)
None
None
None
None
 0.94A 5x1fA-5mwlA:
undetectable
5x1fJ-5mwlA:
undetectable		 5x1fA-5mwlA:
19.60
5x1fJ-5mwlA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		4 / 5 TYR A 392
ARG A 393
MET A 396
THR A 397
 None
 0.78A 5x1fW-5mwlA:
undetectable		 5x1fW-5mwlA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		4 / 6 SER A 454
HIS A 152
GLU A 334
TYR A 450
 None
 1.29A 5x7pA-5mwlA:
undetectable		 5x7pA-5mwlA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		4 / 6 SER A 454
HIS A 152
GLU A 334
TYR A 450
 None
 1.31A 5x7pB-5mwlA:
undetectable		 5x7pB-5mwlA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Q_B_ACRB1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		4 / 6 SER A 454
HIS A 152
GLU A 334
TYR A 450
 None
 1.32A 5x7qB-5mwlA:
undetectable		 5x7qB-5mwlA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7R_B_ACRB1481_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		4 / 6 SER A 454
HIS A 152
GLU A 334
TYR A 450
 None
 1.28A 5x7rB-5mwlA:
undetectable		 5x7rB-5mwlA:
16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		4 / 7 LEU A 452
TYR A 392
MET A 396
THR A 397
 5MY  A 502 (-4.6A)
None
None
None
 0.83A 5xdqA-5mwlA:
undetectable
5xdqJ-5mwlA:
undetectable		 5xdqA-5mwlA:
19.60
5xdqJ-5mwlA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		5 / 12 LEU A 185
ILE A 137
ILE A 132
LEU A 133
ILE A 265
 None
 1.20A 5y2tB-5mwlA:
undetectable		 5y2tB-5mwlA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		4 / 6 TYR A 392
ARG A 393
MET A 396
THR A 397
 None
 1.03A 5zcoN-5mwlA:
undetectable
5zcoW-5mwlA:
undetectable		 5zcoN-5mwlA:
19.60
5zcoW-5mwlA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		4 / 5 TYR A 392
ARG A 393
MET A 396
THR A 397
 None
 0.76A 6nknJ-5mwlA:
undetectable		 6nknJ-5mwlA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		4 / 6 LEU A 452
ARG A 393
MET A 396
THR A 397
 5MY  A 502 (-4.6A)
None
None
None
 1.06A 6nmfN-5mwlA:
undetectable
6nmfW-5mwlA:
undetectable		 6nmfN-5mwlA:
19.60
6nmfW-5mwlA:
8.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5mwl INOSITOL-PENTAKISPHO
SPHATE 2-KINASE
(Mus
musculus) 		4 / 6 LEU A 452
TYR A 392
MET A 396
THR A 397
 5MY  A 502 (-4.6A)
None
None
None
 0.84A 6nmfN-5mwlA:
undetectable
6nmfW-5mwlA:
undetectable		 6nmfN-5mwlA:
19.60
6nmfW-5mwlA:
8.96