SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mx2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWD_F_377F401_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	5mx2	PHOTOSYSTEM II 12 KDA EXTRINSIC PROTEIN (Thermosynechococ cus elongatus)	4 / 7	LEU U 27 PHE U 35 TYR U 21 ARG U 97	None	1.21A	4twdF-5mx2U: undetectable 4twdJ-5mx2U: undetectable	4twdF-5mx2U: 16.45 4twdJ-5mx2U: 16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWD_G_377G401_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	5mx2	PHOTOSYSTEM II 12 KDA EXTRINSIC PROTEIN (Thermosynechococ cus elongatus)	4 / 6	TYR U 21 ARG U 97 LEU U 27 PHE U 35	None	1.15A	4twdF-5mx2U: undetectable 4twdG-5mx2U: undetectable	4twdF-5mx2U: 16.45 4twdG-5mx2U: 16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AN0_A_HISA520_0 (HISTIDINOL DEHYDROGENASE)	5mx2	PHOTOSYSTEM II 12 KDA EXTRINSIC PROTEIN (Thermosynechococ cus elongatus)	4 / 6	GLU U 77 LYS U 72 ARG U 70 GLU U 69	None	1.16A	6an0A-5mx2U: undetectable	6an0A-5mx2U: 16.70

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4TWD_F_377F401_1","CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL","5mx2","PHOTOSYSTEM II 12 KDA EXTRINSIC PROTEIN","Thermosynechococcus elongatus",4,"LEU U  27;PHE U  35;TYR U  21;ARG U  97","None","1.21A","4twdF-5mx2U:undetectable;4twdJ-5mx2U:undetectable","4twdF-5mx2U:16.45;4twdJ-5mx2U:16.45"],["4TWD_G_377G401_1","CYS-LOOP LIGAND-GATED ION CHANNEL;CYS-LOOP LIGAND-GATED ION CHANNEL","5mx2","PHOTOSYSTEM II 12 KDA EXTRINSIC PROTEIN","Thermosynechococcus elongatus",4,"TYR U  21;ARG U  97;LEU U  27;PHE U  35","None","1.15A","4twdF-5mx2U:undetectable;4twdG-5mx2U:undetectable","4twdF-5mx2U:16.45;4twdG-5mx2U:16.45"],["6AN0_A_HISA520_0","HISTIDINOL DEHYDROGENASE","5mx2","PHOTOSYSTEM II 12 KDA EXTRINSIC PROTEIN","Thermosynechococcus elongatus",4,"GLU U  77;LYS U  72;ARG U  70;GLU U  69","None","1.16A","6an0A-5mx2U:undetectable","6an0A-5mx2U:16.70"]]