SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mxf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_A_DVAA8_0
(GRAMICIDIN A)		 5mxf PHOTORHABDUS
ASYMBIOTICA LECTIN
PHL
(Photorhabdus
asymbiotica) 		4 / 4 GLY A 122
VAL A 124
TRP A 104
GLY A  98
 None
 1.27A 1ng8A-5mxfA:
undetectable		 1ng8A-5mxfA:
4.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NG8_B_DVAB8_0
(GRAMICIDIN A)		 5mxf PHOTORHABDUS
ASYMBIOTICA LECTIN
PHL
(Photorhabdus
asymbiotica) 		4 / 4 GLY A 122
VAL A 124
TRP A 104
GLY A  98
 None
 1.27A 1ng8B-5mxfA:
undetectable		 1ng8B-5mxfA:
4.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 5mxf PHOTORHABDUS
ASYMBIOTICA LECTIN
PHL
(Photorhabdus
asymbiotica) 		3 / 3 GLU A  93
TRP A 107
LYS A 277
 None
 1.41A 1qu2A-5mxfA:
undetectable		 1qu2A-5mxfA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_F_TACF3888_1
(ELONGATION FACTOR
EF-TU)		 5mxf PHOTORHABDUS
ASYMBIOTICA LECTIN
PHL
(Photorhabdus
asymbiotica) 		4 / 7 SER A  39
ASP A  40
VAL A  36
LEU A  74
 None
NA  A 405 (-2.8A)
None
None
 1.03A 2hdnE-5mxfA:
undetectable
2hdnF-5mxfA:
undetectable
2hdnH-5mxfA:
undetectable		 2hdnE-5mxfA:
7.05
2hdnF-5mxfA:
19.90
2hdnH-5mxfA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_H_TACH4888_1
(ELONGATION FACTOR
EF-TU)		 5mxf PHOTORHABDUS
ASYMBIOTICA LECTIN
PHL
(Photorhabdus
asymbiotica) 		4 / 7 VAL A  36
LEU A  74
SER A  39
ASP A  40
 None
None
None
NA  A 405 (-2.8A)
 0.99A 2hdnF-5mxfA:
undetectable
2hdnG-5mxfA:
undetectable
2hdnH-5mxfA:
undetectable		 2hdnF-5mxfA:
19.90
2hdnG-5mxfA:
7.05
2hdnH-5mxfA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5mxf PHOTORHABDUS
ASYMBIOTICA LECTIN
PHL
(Photorhabdus
asymbiotica) 		3 / 3 SER A 304
GLY A 305
GLN A 299
 None
 0.45A 3v4tH-5mxfA:
undetectable		 3v4tH-5mxfA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_A_9TPA601_1
(SERUM ALBUMIN)		 5mxf PHOTORHABDUS
ASYMBIOTICA LECTIN
PHL
(Photorhabdus
asymbiotica) 		5 / 12 ALA A 276
ILE A  32
LEU A 294
ARG A 288
GLY A 337
 None
None
None
None
MFU  A 401 (-3.2A)
 1.27A 4l9qA-5mxfA:
undetectable		 4l9qA-5mxfA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_H_BO2H301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5mxf PHOTORHABDUS
ASYMBIOTICA LECTIN
PHL
(Photorhabdus
asymbiotica) 		5 / 12 GLN A 203
ALA A 158
GLY A 137
ALA A 133
THR A  88
 None
 1.28A 4qw1H-5mxfA:
undetectable
4qw1I-5mxfA:
undetectable		 4qw1H-5mxfA:
21.49
4qw1I-5mxfA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_V_BO2V301_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-3)		 5mxf PHOTORHABDUS
ASYMBIOTICA LECTIN
PHL
(Photorhabdus
asymbiotica) 		5 / 12 GLN A 203
ALA A 158
GLY A 137
ALA A 133
THR A  88
 None
 1.29A 4qw1V-5mxfA:
undetectable
4qw1W-5mxfA:
undetectable		 4qw1V-5mxfA:
21.49
4qw1W-5mxfA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YJI_A_TYLA502_1
(ARYL ACYLAMIDASE)		 5mxf PHOTORHABDUS
ASYMBIOTICA LECTIN
PHL
(Photorhabdus
asymbiotica) 		4 / 7 LEU A 265
THR A 297
ALA A 285
ILE A 228
 None
 0.72A 4yjiA-5mxfA:
undetectable		 4yjiA-5mxfA:
24.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_B_FOLB201_1
(DIHYDROFOLATE
REDUCTASE)		 5mxf PHOTORHABDUS
ASYMBIOTICA LECTIN
PHL
(Photorhabdus
asymbiotica) 		3 / 3 ASP A 364
ARG A 144
ARG A  97
 None
 0.96A 5eajB-5mxfA:
undetectable		 5eajB-5mxfA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C06_D_FI8D1404_0
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA
DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 5mxf PHOTORHABDUS
ASYMBIOTICA LECTIN
PHL
(Photorhabdus
asymbiotica) 		4 / 8 ILE A 253
THR A 252
THR A 230
LYS A 277
 None
 1.10A 6c06C-5mxfA:
undetectable		 6c06C-5mxfA:
undetectable