SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5my3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)
5my3 RHO
GTPASE-ACTIVATING
PROTEIN RGD1

(Saccharomyces
cerevisiae)
5 / 12 VAL A 114
LEU A 110
VAL A  37
ALA A 156
ILE A  40
None
1.01A 1epbA-5my3A:
undetectable
1epbA-5my3A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HC4_A_VDXA525_1
(VITAMIN D RECEPTOR)
5my3 RHO
GTPASE-ACTIVATING
PROTEIN RGD1

(Saccharomyces
cerevisiae)
5 / 12 LEU A 110
VAL A 114
SER A  28
VAL A  41
LEU A 161
None
1.15A 2hc4A-5my3A:
undetectable
2hc4A-5my3A:
11.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)
5my3 RHO
GTPASE-ACTIVATING
PROTEIN RGD1

(Saccharomyces
cerevisiae)
4 / 6 LEU A 154
LEU A 157
ILE A 143
ARG A 155
None
0.93A 2rlfA-5my3A:
undetectable
2rlfB-5my3A:
undetectable
2rlfA-5my3A:
22.22
2rlfB-5my3A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)
5my3 RHO
GTPASE-ACTIVATING
PROTEIN RGD1

(Saccharomyces
cerevisiae)
5 / 12 PRO A  38
ILE A  75
VAL A  41
LEU A  71
PHE A  22
None
1.28A 5bykA-5my3A:
undetectable
5bykA-5my3A:
undetectable