SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5my5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		 5my5 ABC TRANSPORTER
PERIPLASMIC
SUBSTRATE-BINDING
PROTEIN
(Desulfovibrio
alaskensis) 		5 / 12 ALA A 219
GLY A  73
THR A  74
LEU A  34
LEU A   5
 None
 1.27A 1jipA-5my5A:
undetectable		 1jipA-5my5A:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGQ_A_PCFA1275_0
(WNT INHIBITORY
FACTOR 1)		 5my5 ABC TRANSPORTER
PERIPLASMIC
SUBSTRATE-BINDING
PROTEIN
(Desulfovibrio
alaskensis) 		6 / 12 LEU A   5
LEU A  79
ILE A  55
ILE A 235
MET A 226
PHE A 222
 None
 1.50A 2ygqA-5my5A:
undetectable		 2ygqA-5my5A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EM2_A_SALA504_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR SAR2349)		 5my5 ABC TRANSPORTER
PERIPLASMIC
SUBSTRATE-BINDING
PROTEIN
(Desulfovibrio
alaskensis) 		4 / 8 GLY A  88
LEU A 190
ILE A  86
ILE A 108
 None
 0.82A 4em2A-5my5A:
undetectable		 4em2A-5my5A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_A_ACTA1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 5my5 ABC TRANSPORTER
PERIPLASMIC
SUBSTRATE-BINDING
PROTEIN
(Desulfovibrio
alaskensis) 		4 / 5 GLY A 165
ALA A 160
GLY A  88
PRO A  89
 None
 0.81A 4u9uA-5my5A:
undetectable		 4u9uA-5my5A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_B_ACTB1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 5my5 ABC TRANSPORTER
PERIPLASMIC
SUBSTRATE-BINDING
PROTEIN
(Desulfovibrio
alaskensis) 		4 / 5 GLY A 165
ALA A 160
GLY A  88
PRO A  89
 None
 0.83A 4u9uB-5my5A:
undetectable		 4u9uB-5my5A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XLD_A_BRLA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5my5 ABC TRANSPORTER
PERIPLASMIC
SUBSTRATE-BINDING
PROTEIN
(Desulfovibrio
alaskensis) 		5 / 12 GLY A  17
SER A  12
LEU A  57
PHE A 246
MET A  80
 None
 1.50A 4xldA-5my5A:
undetectable		 4xldA-5my5A:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EQP_A_BUWA601_1
(CHOLINESTERASE)		 5my5 ABC TRANSPORTER
PERIPLASMIC
SUBSTRATE-BINDING
PROTEIN
(Desulfovibrio
alaskensis) 		4 / 8 GLY A 119
GLN A 148
THR A 149
SER A 122
 None
 0.86A 6eqpA-5my5A:
undetectable		 6eqpA-5my5A:
14.23