SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5myu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_L_CSCL1383_2
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5myu TYPE VI SECRETION
SYSTEM PROTEIN IMPC
(Vibrio
cholerae) 		4 / 4 THR A 348
LEU A 347
MET A 349
MET A 477
 None
 1.48A 2vavL-5myuA:
0.0		 2vavL-5myuA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_D_BRLD478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5myu TYPE VI SECRETION
SYSTEM PROTEIN IMPC
(Vibrio
cholerae) 		4 / 4 ILE A 298
GLN A 388
ILE A 190
LEU A 385
 None
 1.23A 3dzyD-5myuA:
undetectable		 3dzyD-5myuA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_D_ROFD904_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 5myu TYPE VI SECRETION
SYSTEM PROTEIN IMPC
(Vibrio
cholerae) 		3 / 3 ASN A 276
MET A 349
PHE A 243
 None
 0.86A 3g4lD-5myuA:
undetectable		 3g4lD-5myuA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB303_0
(DISULFIDE
INTERCHANGE PROTEIN)		 5myu TYPE VI SECRETION
SYSTEM PROTEIN IMPC
(Vibrio
cholerae) 		4 / 4 LEU A 206
ALA A 240
VAL A 193
PRO A 195
 None
 1.08A 3gv1B-5myuA:
undetectable		 3gv1B-5myuA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMA_D_ADND604_1
(PYRUVATE KINASE)		 5myu TYPE VI SECRETION
SYSTEM PROTEIN IMPC
(Vibrio
cholerae) 		3 / 3 ARG A 293
GLU A 110
ASN A 111
 None
 0.90A 4imaD-5myuA:
undetectable		 4imaD-5myuA:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_1_PQN12001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 5myu TYPE VI SECRETION
SYSTEM PROTEIN IMPC
(Vibrio
cholerae) 		5 / 11 GLY A 343
ALA A 233
LEU A 236
GLY A 237
ALA A 131
 None
 0.94A 4l6v1-5myuA:
undetectable
4l6v6-5myuA:
undetectable		 4l6v1-5myuA:
19.09
4l6v6-5myuA:
16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M5M_A_DX4A401_0
(2-AMINO-4-HYDROXY-6-
HYDROXYMETHYLDIHYDRO
PTERIDINE
PYROPHOSPHOKINASE)		 5myu TYPE VI SECRETION
SYSTEM PROTEIN IMPC
(Vibrio
cholerae) 		4 / 8 GLY A 275
LEU A  99
TRP A  96
PHE A 279
 None
 1.11A 4m5mA-5myuA:
undetectable		 4m5mA-5myuA:
16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_B_SAMB401_0
(PAVINE
N-METHYLTRANSFERASE)		 5myu TYPE VI SECRETION
SYSTEM PROTEIN IMPC
(Vibrio
cholerae) 		5 / 12 PHE A 102
GLY A 275
GLY A  98
THR A 327
ALA A 278
 None
 1.11A 5kpcB-5myuA:
undetectable		 5kpcB-5myuA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_2
(SCRFP-TAG,GP41)		 5myu TYPE VI SECRETION
SYSTEM PROTEIN IMPC
(Vibrio
cholerae) 		3 / 3 LYS A 223
TRP A 224
SER A 226
 None
 1.12A 5nwwA-5myuA:
undetectable		 5nwwA-5myuA:
7.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 5myu TYPE VI SECRETION
SYSTEM PROTEIN IMPC
(Vibrio
cholerae) 		3 / 3 HIS A 269
GLU A 270
TRP A 274
 None
 1.02A 5odiD-5myuA:
undetectable		 5odiD-5myuA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 5myu TYPE VI SECRETION
SYSTEM PROTEIN IMPC
(Vibrio
cholerae) 		3 / 3 HIS A 269
GLU A 270
TRP A 274
 None
 0.98A 5odqD-5myuA:
undetectable		 5odqD-5myuA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODR_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 5myu TYPE VI SECRETION
SYSTEM PROTEIN IMPC
(Vibrio
cholerae) 		3 / 3 HIS A 269
GLU A 270
TRP A 274
 None
 1.04A 5odrD-5myuA:
undetectable		 5odrD-5myuA:
14.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 5myu TYPE VI SECRETION
SYSTEM PROTEIN IMPC
(Vibrio
cholerae) 		4 / 6 LYS A 121
LEU A 124
PHE A 128
LEU A 139
 None
 1.15A 5x19P-5myuA:
undetectable		 5x19P-5myuA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5myu TYPE VI SECRETION
SYSTEM PROTEIN IMPC
(Vibrio
cholerae) 		4 / 5 ARG A 350
MET A 349
THR A 348
LEU A 347
 None
 0.83A 6nknW-5myuA:
undetectable		 6nknW-5myuA:
10.34