SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mz9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)		 5mz9 -
(-) 		4 / 8 TYR A 322
THR A 343
VAL A 547
VAL A 543
 None
 1.05A 1dz9A-5mz9A:
undetectable		 1dz9A-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDS_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)		 5mz9 -
(-) 		5 / 12 SER A 626
VAL A 627
GLY A 628
SER A 300
PHE A 698
 None
 1.38A 1fdsA-5mz9A:
undetectable		 1fdsA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_2
(HIV-1 PROTEASE)		 5mz9 -
(-) 		5 / 9 ALA A 303
GLY A 387
ILE A 385
VAL A 547
ILE A 395
 None
 0.99A 1hpvB-5mz9A:
undetectable		 1hpvB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_3
(HIV-1 PROTEASE)		 5mz9 -
(-) 		5 / 12 ALA A 303
GLY A 387
ILE A 385
VAL A 547
ILE A 395
 None
 0.93A 1hxbB-5mz9A:
undetectable		 1hxbB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_3
(HIV-1 PROTEASE)		 5mz9 -
(-) 		5 / 12 LEU A 552
ALA A 303
GLY A 387
ILE A 385
VAL A 547
 None
 1.04A 1hxbB-5mz9A:
undetectable		 1hxbB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JFF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 5mz9 -
(-) 		5 / 12 ASP A 731
LEU A 159
LEU A 269
THR A 158
PRO A 720
 None
 1.16A 1jffB-5mz9A:
undetectable		 1jffB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)		 5mz9 -
(-) 		4 / 8 TYR A 322
THR A 343
VAL A 547
VAL A 543
 None
 1.01A 1o76B-5mz9A:
undetectable		 1o76B-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 5mz9 -
(-) 		5 / 11 ALA A 303
GLY A 387
ILE A 385
VAL A 547
ILE A 395
 None
 0.92A 1sduA-5mz9A:
undetectable		 1sduA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T3R_A_017A1200_2
(PROTEASE RETROPEPSIN)		 5mz9 -
(-) 		6 / 11 LEU A 552
ALA A 303
GLY A 387
ILE A 385
VAL A 547
ILE A 395
 None
 1.13A 1t3rB-5mz9A:
undetectable		 1t3rB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T85_A_CAMA422_0
(CYTOCHROME P450-CAM)		 5mz9 -
(-) 		4 / 7 TYR A 322
THR A 343
VAL A 547
VAL A 543
 None
 1.04A 1t85A-5mz9A:
undetectable		 1t85A-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 5mz9 -
(-) 		4 / 7 TYR A 322
THR A 343
VAL A 547
VAL A 543
 None
 1.03A 1t87A-5mz9A:
undetectable		 1t87A-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_A_CAMA1416_0
(CYTOCHROME P450-CAM)		 5mz9 -
(-) 		4 / 8 TYR A 322
THR A 343
VAL A 547
VAL A 543
 None
 1.05A 1uyuA-5mz9A:
undetectable		 1uyuA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_A_CAMA1416_0
(CYTOCHROME P450-CAM)		 5mz9 -
(-) 		4 / 8 TYR A 322
VAL A 547
THR A 573
VAL A 543
 None
 1.13A 1uyuA-5mz9A:
undetectable		 1uyuA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 5mz9 -
(-) 		4 / 8 TYR A 322
THR A 343
VAL A 547
VAL A 543
 None
 1.01A 1uyuB-5mz9A:
undetectable		 1uyuB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 5mz9 -
(-) 		4 / 7 TYR A 322
THR A 343
VAL A 547
VAL A 543
 None
 1.04A 1yrcA-5mz9A:
undetectable		 1yrcA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 5mz9 -
(-) 		4 / 7 TYR A 322
THR A 343
VAL A 547
VAL A 543
 None
 1.02A 1yrdA-5mz9A:
undetectable		 1yrdA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_1
(POL POLYPROTEIN)		 5mz9 -
(-) 		5 / 9 LEU A 552
GLY A 387
ILE A 385
VAL A 547
ILE A 395
 None
 1.10A 2avoA-5mz9A:
undetectable		 2avoA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 5mz9 -
(-) 		5 / 9 LEU A 501
LEU A 148
ILE A 502
PHE A 373
LEU A 360
 None
 1.26A 2f78A-5mz9A:
undetectable		 2f78A-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 5mz9 -
(-) 		5 / 9 LEU A 501
LEU A 148
ILE A 502
PHE A 373
LEU A 360
 None
 1.27A 2f78B-5mz9A:
undetectable		 2f78B-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 5mz9 -
(-) 		5 / 9 LEU A 501
LEU A 148
ILE A 502
PHE A 373
LEU A 360
 None
 1.30A 2f7aA-5mz9A:
undetectable		 2f7aA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7A_B_BEZB1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 5mz9 -
(-) 		5 / 9 LEU A 501
LEU A 148
ILE A 502
PHE A 373
LEU A 360
 None
 1.21A 2f7aB-5mz9A:
undetectable		 2f7aB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_2
(POL POLYPROTEIN)		 5mz9 -
(-) 		5 / 12 ALA A 303
GLY A 387
ILE A 385
VAL A 547
ILE A 395
 None
 0.88A 2f80B-5mz9A:
undetectable		 2f80B-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_A_CAMA1420_0
(CYTOCHROME P450-CAM)		 5mz9 -
(-) 		4 / 6 TYR A 322
THR A 343
VAL A 547
VAL A 543
 None
 1.04A 2feuA-5mz9A:
undetectable		 2feuA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FEU_B_CAMB1421_0
(CYTOCHROME P450-CAM)		 5mz9 -
(-) 		4 / 7 TYR A 322
THR A 343
VAL A 547
VAL A 543
 None
 1.02A 2feuB-5mz9A:
undetectable		 2feuB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 5mz9 -
(-) 		5 / 12 ASP A 731
LEU A 159
LEU A 269
THR A 158
PRO A 720
 None
 1.17A 2hxfB-5mz9A:
undetectable		 2hxfB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXH_B_TA1B601_1
(TUBULIN BETA CHAIN)		 5mz9 -
(-) 		5 / 12 ASP A 731
LEU A 159
LEU A 269
THR A 158
PRO A 720
 None
 1.17A 2hxhB-5mz9A:
undetectable		 2hxhB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1291_1
(FICOLIN-2)		 5mz9 -
(-) 		4 / 6 LEU A 534
SER A 435
ASP A 441
GLU A 532
 None
 1.14A 2j2pE-5mz9A:
undetectable
2j2pF-5mz9A:
undetectable		 2j2pE-5mz9A:
undetectable
2j2pF-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1121_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5mz9 -
(-) 		4 / 5 SER A 767
VAL A 765
SER A 711
VAL A 737
 None
 1.24A 2j9cA-5mz9A:
undetectable
2j9cB-5mz9A:
undetectable
2j9cC-5mz9A:
undetectable		 2j9cA-5mz9A:
undetectable
2j9cB-5mz9A:
undetectable
2j9cC-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_2
(PROTEASE)		 5mz9 -
(-) 		5 / 9 ALA A 303
GLY A 387
ILE A 385
VAL A 547
ILE A 395
 None
 0.85A 2o4pB-5mz9A:
undetectable		 2o4pB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P4N_B_TA1B601_1
(TUBULIN BETA CHAIN)		 5mz9 -
(-) 		5 / 12 ASP A 731
LEU A 159
LEU A 269
THR A 158
PRO A 720
 None
 1.17A 2p4nB-5mz9A:
undetectable		 2p4nB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6K_A_ADNA699_1
(CHLORINASE)		 5mz9 -
(-) 		4 / 7 PHE A  43
TYR A  40
PRO A  42
THR A  27
 None
 1.47A 2q6kA-5mz9A:
undetectable		 2q6kA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VDM_B_AGGB1462_1
(INTEGRIN ALPHA-IIB
INTEGRIN BETA-3)		 5mz9 -
(-) 		5 / 12 PHE A 400
SER A 585
TYR A 584
SER A 621
ALA A 520
 None
 1.33A 2vdmA-5mz9A:
7.2
2vdmB-5mz9A:
undetectable		 2vdmA-5mz9A:
undetectable
2vdmB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WBE_B_TA1B1439_1
(TUBULIN BETA-2B
CHAIN)		 5mz9 -
(-) 		5 / 12 ASP A 731
LEU A 159
LEU A 269
THR A 158
PRO A 720
 None
 1.16A 2wbeB-5mz9A:
undetectable		 2wbeB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_A_TPFA1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 5mz9 -
(-) 		5 / 10 TYR A 322
MET A 312
THR A 573
LEU A 345
VAL A 543
 None
 1.35A 2wuzA-5mz9A:
undetectable		 2wuzA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WUZ_B_TPFB1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE
, PUTATIVE)		 5mz9 -
(-) 		5 / 10 TYR A 322
MET A 312
THR A 573
LEU A 345
VAL A 543
 None
 1.34A 2wuzB-5mz9A:
undetectable		 2wuzB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUH_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5mz9 -
(-) 		4 / 6 TYR A 322
THR A 343
VAL A 547
VAL A 543
 None
 1.03A 2zuhA-5mz9A:
undetectable		 2zuhA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5mz9 -
(-) 		4 / 6 TYR A 322
THR A 343
VAL A 547
VAL A 543
 None
 1.04A 2zuiA-5mz9A:
undetectable		 2zuiA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5mz9 -
(-) 		4 / 7 TYR A 322
THR A 343
VAL A 547
VAL A 543
 None
 1.05A 2zwuA-5mz9A:
undetectable		 2zwuA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_A_VDYA6178_1
(VITAMIN D
HYDROXYLASE)		 5mz9 -
(-) 		5 / 11 THR A  70
ILE A 388
ASN A  73
ILE A 309
LEU A 552
 None
 1.21A 3a51A-5mz9A:
undetectable		 3a51A-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_D_VDYD6178_1
(VITAMIN D
HYDROXYLASE)		 5mz9 -
(-) 		5 / 12 THR A  70
ILE A 388
ASN A  73
ILE A 309
LEU A 552
 None
 1.21A 3a51D-5mz9A:
undetectable		 3a51D-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_2
(GLUCOSYLTRANSFERASE-
SI)		 5mz9 -
(-) 		3 / 3 LEU A 207
TRP A 220
TYR A 510
 None
 0.76A 3aicA-5mz9A:
undetectable		 3aicA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_2
(GLUCOSYLTRANSFERASE-
SI)		 5mz9 -
(-) 		3 / 3 LEU A 207
TRP A 220
TYR A 510
 None
 0.74A 3aicB-5mz9A:
undetectable		 3aicB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_2
(GLUCOSYLTRANSFERASE-
SI)		 5mz9 -
(-) 		3 / 3 LEU A 207
TRP A 220
TYR A 510
 None
 0.73A 3aicE-5mz9A:
undetectable		 3aicE-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_2
(GLUCOSYLTRANSFERASE-
SI)		 5mz9 -
(-) 		3 / 3 LEU A 207
TRP A 220
TYR A 510
 None
 0.74A 3aicF-5mz9A:
undetectable		 3aicF-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_2
(GLUCOSYLTRANSFERASE-
SI)		 5mz9 -
(-) 		3 / 3 LEU A 207
TRP A 220
TYR A 510
 None
 0.71A 3aicG-5mz9A:
undetectable		 3aicG-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_2
(GLUCOSYLTRANSFERASE-
SI)		 5mz9 -
(-) 		3 / 3 LEU A 207
TRP A 220
TYR A 510
 None
 0.75A 3aicH-5mz9A:
undetectable		 3aicH-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_1
(N,N-DIMETHYLTRANSFER
ASE)		 5mz9 -
(-) 		3 / 3 TYR A 510
GLU A 224
ASP A 723
 None
 0.83A 3bxoA-5mz9A:
2.0		 3bxoA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_1
(N,N-DIMETHYLTRANSFER
ASE)		 5mz9 -
(-) 		3 / 3 TYR A 510
GLU A 224
ASP A 723
 None
 0.78A 3bxoB-5mz9A:
undetectable		 3bxoB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYW_A_017A201_2
(HIV-1 PROTEASE)		 5mz9 -
(-) 		5 / 12 ALA A 303
GLY A 387
ILE A 385
VAL A 547
ILE A 395
 None
 0.87A 3cywB-5mz9A:
undetectable		 3cywB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Y_A_ROCA201_2
(HIV-1 PROTEASE)		 5mz9 -
(-) 		5 / 9 LEU A 552
GLY A 387
ILE A 385
VAL A 547
ILE A 395
 None
 1.11A 3d1yB-5mz9A:
undetectable		 3d1yB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D20_A_017A201_2
(HIV-1 PROTEASE)		 5mz9 -
(-) 		5 / 12 ALA A 303
GLY A 387
ILE A 385
VAL A 547
ILE A 395
 None
 0.89A 3d20B-5mz9A:
undetectable		 3d20B-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCO_B_TA1B601_1
(BOVINE BETA TUBULIN)		 5mz9 -
(-) 		5 / 12 ASP A 731
LEU A 159
LEU A 269
THR A 158
PRO A 720
 None
 1.17A 3dcoB-5mz9A:
undetectable		 3dcoB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EDL_B_TA1B601_1
(BETA TUBULIN)		 5mz9 -
(-) 		5 / 12 ASP A 731
LEU A 159
LEU A 269
THR A 158
PRO A 720
 None
 1.17A 3edlB-5mz9A:
undetectable		 3edlB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_2
(PROTEASE)		 5mz9 -
(-) 		5 / 9 ALA A 303
GLY A 387
ILE A 385
VAL A 547
ILE A 395
 None
 0.96A 3ekvB-5mz9A:
undetectable		 3ekvB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 5mz9 -
(-) 		4 / 7 TYR A 322
THR A 343
VAL A 547
VAL A 543
 None
 1.04A 3fwfA-5mz9A:
undetectable		 3fwfA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWI_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 5mz9 -
(-) 		4 / 7 TYR A 322
THR A 343
VAL A 547
VAL A 543
 None
 1.03A 3fwiA-5mz9A:
undetectable		 3fwiA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 5mz9 -
(-) 		4 / 7 TYR A 322
THR A 343
VAL A 547
VAL A 543
 None
 1.05A 3fwjA-5mz9A:
undetectable		 3fwjA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_A_EPAA1_1
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 5mz9 -
(-) 		5 / 10 VAL A 325
ILE A 385
LEU A  79
VAL A 111
LEU A 132
 None
 0.99A 3gwxA-5mz9A:
undetectable		 3gwxA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I9J_B_NCAB302_0
(ADP-RIBOSYL CYCLASE)		 5mz9 -
(-) 		4 / 6 LEU A 709
GLU A 784
ASN A 804
SER A 741
 None
 1.40A 3i9jB-5mz9A:
undetectable		 3i9jB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IZ0_B_TA1B820_1
(BETA TUBULIN, CHAIN
B FROM PDB 1JFF)		 5mz9 -
(-) 		5 / 12 ASP A 731
LEU A 159
LEU A 269
THR A 158
PRO A 720
 None
 1.15A 3iz0B-5mz9A:
undetectable		 3iz0B-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_2
(GAG-POL POLYPROTEIN)		 5mz9 -
(-) 		5 / 12 ALA A 303
GLY A 387
ILE A 385
VAL A 547
ILE A 395
 None
 0.87A 3jvyB-5mz9A:
undetectable		 3jvyB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 5mz9 -
(-) 		4 / 6 PHE A  43
PHE A 904
TYR A 910
THR A  41
 None
 1.13A 3lb3B-5mz9A:
undetectable		 3lb3B-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_2
(HIV-1 PROTEASE)		 5mz9 -
(-) 		5 / 11 ALA A 303
GLY A 387
ILE A 385
VAL A 547
ILE A 395
 None
 0.95A 3lzvB-5mz9A:
undetectable		 3lzvB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_1
(PROTEASE)		 5mz9 -
(-) 		5 / 12 ALA A 303
GLY A 387
ILE A 385
VAL A 547
ILE A 395
 None
 0.92A 3ndwA-5mz9A:
undetectable		 3ndwA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ4_X_DXCX75_0
(CYTOCHROME C7)		 5mz9 -
(-) 		5 / 9 LEU A 345
LYS A 301
ILE A 395
PHE A 397
GLY A 399
 None
 1.43A 3sj4X-5mz9A:
undetectable		 3sj4X-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYE_B_YTZB902_1
(DIHYDROPTEROATE
SYNTHASE)		 5mz9 -
(-) 		3 / 3 PHE A 378
LYS A 567
SER A 558
 None
 1.27A 3tyeB-5mz9A:
undetectable		 3tyeB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5mz9 -
(-) 		4 / 7 TYR A 322
THR A 343
VAL A 547
VAL A 543
 None
 1.03A 3wrhA-5mz9A:
undetectable		 3wrhA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5mz9 -
(-) 		4 / 7 TYR A 322
THR A 343
VAL A 547
VAL A 543
 None
 1.04A 3wrjA-5mz9A:
undetectable		 3wrjA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5mz9 -
(-) 		4 / 7 TYR A 322
THR A 343
VAL A 547
VAL A 543
 None
 1.02A 3wrlA-5mz9A:
undetectable		 3wrlA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 5mz9 -
(-) 		5 / 12 ILE A 633
GLY A 647
ILE A 546
ASP A 666
ASN A 306
 None
 1.09A 4a81A-5mz9A:
undetectable		 4a81A-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AE1_B_NCAB1536_0
(DIPHTHERIA TOXIN)		 5mz9 -
(-) 		4 / 5 HIS A 374
GLY A 361
TYR A 362
GLU A 364
 None
 1.13A 4ae1B-5mz9A:
undetectable		 4ae1B-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3A_A_TACA222_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 5mz9 -
(-) 		5 / 12 LEU A 507
ASN A 160
PHE A 607
PRO A 579
GLN A 540
 None
 1.49A 4b3aA-5mz9A:
undetectable		 4b3aA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_1
(ASPARTYL PROTEASE)		 5mz9 -
(-) 		5 / 10 ALA A 303
GLY A 387
ILE A 385
VAL A 547
ILE A 395
 None
 0.96A 4dqcA-5mz9A:
undetectable		 4dqcA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_1
(ASPARTYL PROTEASE)		 5mz9 -
(-) 		5 / 11 ALA A 303
GLY A 387
ILE A 385
VAL A 547
ILE A 395
 None
 0.96A 4dqeA-5mz9A:
undetectable		 4dqeA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_1
(WILD-TYPE HIV-1
PROTEASE DIMER)		 5mz9 -
(-) 		5 / 11 ALA A 303
GLY A 387
ILE A 385
VAL A 547
ILE A 395
 None
 0.99A 4dqhA-5mz9A:
undetectable		 4dqhA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)		 5mz9 -
(-) 		4 / 7 ILE A 278
LEU A 275
LYS A 725
GLY A 724
 None
 0.96A 4hbfA-5mz9A:
undetectable		 4hbfA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_1
(PROTEASE)		 5mz9 -
(-) 		5 / 12 ALA A 303
GLY A 387
ILE A 385
VAL A 547
ILE A 395
 None
 0.97A 4hlaA-5mz9A:
undetectable		 4hlaA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HLA_A_017A200_2
(PROTEASE)		 5mz9 -
(-) 		5 / 11 ALA A 303
GLY A 387
ILE A 385
VAL A 547
ILE A 395
 None
 0.94A 4hlaB-5mz9A:
undetectable		 4hlaB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4B_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5mz9 -
(-) 		4 / 8 TYR A 322
THR A 343
VAL A 547
VAL A 543
 None
 1.01A 4l4bA-5mz9A:
undetectable		 4l4bA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4D_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5mz9 -
(-) 		4 / 8 TYR A 322
THR A 343
VAL A 547
VAL A 543
 None
 0.97A 4l4dA-5mz9A:
undetectable		 4l4dA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4E_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5mz9 -
(-) 		4 / 8 TYR A 322
THR A 343
VAL A 547
VAL A 543
 None
 1.00A 4l4eA-5mz9A:
undetectable		 4l4eA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4F_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5mz9 -
(-) 		4 / 8 TYR A 322
THR A 343
VAL A 547
VAL A 543
 None
 1.01A 4l4fA-5mz9A:
undetectable		 4l4fA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5mz9 -
(-) 		4 / 7 TYR A 322
THR A 343
VAL A 547
VAL A 543
 None
 1.03A 4l4gA-5mz9A:
undetectable		 4l4gA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_B_MRVB1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 5mz9 -
(-) 		4 / 5 TYR A 577
THR A 158
LEU A 154
THR A 652
 None
 1.50A 4mbsB-5mz9A:
undetectable		 4mbsB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_2
(PROTEASE)		 5mz9 -
(-) 		5 / 10 LEU A 552
ALA A 303
GLY A 387
ILE A 385
ILE A 395
 None
 1.10A 4njuD-5mz9A:
undetectable		 4njuD-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_C7HA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5mz9 -
(-) 		4 / 5 TYR A 213
GLY A 403
TYR A 510
GLY A 511
 None
 1.00A 5ayfA-5mz9A:
undetectable		 5ayfA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2Q_A_ACTA1728_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)		 5mz9 -
(-) 		3 / 3 ASN A 823
SER A 829
ARG A 834
 None
 0.80A 5b2qA-5mz9A:
undetectable		 5b2qA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DWK_C_ACTC207_0
(DIACYLGLYCEROL
KINASE)		 5mz9 -
(-) 		4 / 5 ALA A 504
GLU A 151
ASN A 211
GLU A 224
 None
 1.17A 5dwkC-5mz9A:
undetectable		 5dwkC-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5mz9 -
(-) 		3 / 3 ASP A  61
LEU A 281
ARG A 288
 None
 0.81A 5e8qA-5mz9A:
undetectable		 5e8qA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 5mz9 -
(-) 		4 / 5 GLY A 654
PRO A 506
THR A 652
GLN A 540
 None
 1.14A 5h5fA-5mz9A:
undetectable		 5h5fA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNW_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 5mz9 -
(-) 		5 / 12 ASP A 731
LEU A 159
LEU A 269
THR A 158
PRO A 720
 None
 1.16A 5hnwB-5mz9A:
undetectable		 5hnwB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNY_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 5mz9 -
(-) 		5 / 12 ASP A 731
LEU A 159
LEU A 269
THR A 158
PRO A 720
 None
 1.14A 5hnyB-5mz9A:
undetectable		 5hnyB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_A_VDYA201_1
(CDL2.2)		 5mz9 -
(-) 		5 / 12 LEU A 275
LEU A 384
ILE A 502
GLU A 224
THR A 158
 None
 1.01A 5ienA-5mz9A:
2.7		 5ienA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_2
(CDL2.2)		 5mz9 -
(-) 		5 / 12 LEU A 275
LEU A 384
ILE A 502
GLU A 224
THR A 158
 None
 1.05A 5ienB-5mz9A:
4.5		 5ienB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_A_1GNA615_1
(PHIAB6 TAILSPIKE)		 5mz9 -
(-) 		3 / 3 TYR A 439
TYR A 544
GLN A 574
 None
 1.17A 5jsdA-5mz9A:
undetectable
5jsdB-5mz9A:
undetectable		 5jsdA-5mz9A:
undetectable
5jsdB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB606_1
(PHIAB6 TAILSPIKE)		 5mz9 -
(-) 		3 / 3 TYR A 439
TYR A 544
GLN A 574
 None
 1.16A 5jsdB-5mz9A:
undetectable
5jsdC-5mz9A:
undetectable		 5jsdB-5mz9A:
undetectable
5jsdC-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB618_1
(PHIAB6 TAILSPIKE)		 5mz9 -
(-) 		3 / 3 THR A 430
SER A 536
TYR A 577
 None
 0.89A 5jsdB-5mz9A:
undetectable		 5jsdB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_A_1GNA608_1
(PHIAB6 TAILSPIKE)		 5mz9 -
(-) 		3 / 3 THR A 430
SER A 536
TYR A 577
 None
 0.87A 5jseA-5mz9A:
undetectable		 5jseA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_B_1GNB611_1
(PHIAB6 TAILSPIKE)		 5mz9 -
(-) 		3 / 3 THR A 430
SER A 536
TYR A 577
 None
 0.86A 5jseB-5mz9A:
undetectable		 5jseB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSE_C_1GNC611_1
(PHIAB6 TAILSPIKE)		 5mz9 -
(-) 		3 / 3 THR A 430
SER A 536
TYR A 577
 None
 0.86A 5jseC-5mz9A:
undetectable		 5jseC-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_1
(PROTEASE PR5-DRV)		 5mz9 -
(-) 		5 / 10 ALA A 303
GLY A 387
ILE A 385
VAL A 547
ILE A 395
 None
 0.98A 5kr1A-5mz9A:
undetectable		 5kr1A-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_2
(PROTEASE PR5-SQV)		 5mz9 -
(-) 		5 / 9 LEU A 552
GLY A 387
ILE A 385
VAL A 547
ILE A 395
 None
 1.15A 5kr2D-5mz9A:
undetectable		 5kr2D-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LBT_A_6T0A304_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5mz9 -
(-) 		5 / 10 GLY A 655
GLY A 654
TYR A 584
PHE A 714
ILE A 738
 None
 1.34A 5lbtA-5mz9A:
undetectable
5lbtB-5mz9A:
undetectable		 5lbtA-5mz9A:
undetectable
5lbtB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_1
(CYTOCHROME P450 3A4)		 5mz9 -
(-) 		5 / 12 SER A  50
ILE A 122
THR A 777
ILE A 790
ALA A  44
 PO4  A1002 (-4.4A)
None
None
None
None
 1.12A 5vceA-5mz9A:
undetectable		 5vceA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_1
(REGULATORY PROTEIN
TETR)		 5mz9 -
(-) 		4 / 8 GLN A 231
GLY A 232
GLU A 166
ASP A 236
 None
 1.04A 5vlmD-5mz9A:
undetectable		 5vlmD-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WK9_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5mz9 -
(-) 		4 / 7 TYR A 322
THR A 343
VAL A 547
VAL A 543
 None
 1.00A 5wk9A-5mz9A:
undetectable		 5wk9A-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 5mz9 -
(-) 		4 / 5 VAL A 737
THR A 739
LEU A 776
VAL A  30
 None
 1.03A 6bqgA-5mz9A:
undetectable		 6bqgA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CLX_A_SAMA401_0
(O-METHYLTRANSFERASE)		 5mz9 -
(-) 		5 / 12 ALA A 201
GLY A 511
GLY A 204
PHE A 607
ASP A 519
 SLT  A1003 ( 4.4A)
None
None
None
None
 1.25A 6clxA-5mz9A:
undetectable		 6clxA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIF_B_TPVB201_1
(HIV-1 PROTEASE)		 5mz9 -
(-) 		5 / 12 ALA A 303
GLY A 387
ILE A 385
VAL A 547
ILE A 395
 None
 0.83A 6difB-5mz9A:
undetectable		 6difB-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_1
(STIE PROTEIN)		 5mz9 -
(-) 		4 / 5 THR A 365
THR A 420
GLN A 492
ASP A 422
 None
 1.38A 6ectA-5mz9A:
undetectable		 6ectA-5mz9A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EQP_A_BUWA601_1
(CHOLINESTERASE)		 5mz9 -
(-) 		4 / 8 GLN A 380
THR A 379
PHE A 397
TYR A 322
 None
 1.00A 6eqpA-5mz9A:
undetectable		 6eqpA-5mz9A:
undetectable