SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mzo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2503_0
(FERROCHELATASE)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		4 / 4 LEU A1399
PRO A1400
LEU A1378
ARG A1377
 None
 1.37A 1hrkB-5mzoA:
undetectable		 1hrkB-5mzoA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_ACTA600_0
(HISTONE
METHYLTRANSFERASE
DOT1L)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		4 / 5 LEU A1126
VAL A1124
TYR A1090
THR A1132
 None
 0.87A 1nw3A-5mzoA:
undetectable		 1nw3A-5mzoA:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_A_SAMA302_1
(HYPOTHETICAL PROTEIN
PH0226)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		4 / 4 TYR A 960
ARG A 958
ASP A 362
ASP A 880
 None
 1.39A 1ve3A-5mzoA:
undetectable		 1ve3A-5mzoA:
10.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE3_B_SAMB301_1
(HYPOTHETICAL PROTEIN
PH0226)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		4 / 4 TYR A 960
ARG A 958
ASP A 362
ASP A 880
 None
 1.38A 1ve3B-5mzoA:
2.0		 1ve3B-5mzoA:
10.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_2
(CES1 PROTEIN)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		4 / 4 LEU A 373
PRO A 883
ILE A 361
LEU A 360
 None
 1.17A 1ya4C-5mzoA:
undetectable		 1ya4C-5mzoA:
16.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_A_SNLA502_2
(MINERALOCORTICOID
RECEPTOR)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		4 / 6 LEU A 355
LEU A 353
LEU A 941
LEU A 933
 None
 1.05A 2ab2A-5mzoA:
undetectable		 2ab2A-5mzoA:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AB2_B_SNLB503_2
(MINERALOCORTICOID
RECEPTOR)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		4 / 5 LEU A 355
LEU A 353
LEU A 941
LEU A 933
 None
 1.03A 2ab2B-5mzoA:
undetectable		 2ab2B-5mzoA:
10.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1604_0
(FERROCHELATASE)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		4 / 4 LEU A1399
PRO A1400
LEU A1378
ARG A1377
 None
 1.42A 2hrcB-5mzoA:
undetectable		 2hrcB-5mzoA:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		4 / 4 LEU A1399
PRO A1400
LEU A1378
ARG A1377
 None
 1.34A 2pnjB-5mzoA:
undetectable		 2pnjB-5mzoA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_1
(UNCHARACTERIZED
PROTEIN TFU_2867)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		3 / 3 ASN A 230
ARG A 110
ASP A 971
 None
EDO  A1615 (-2.9A)
None
 0.99A 2qe6A-5mzoA:
undetectable		 2qe6A-5mzoA:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_B_BEZB143_0
(PUTATIVE REDOX
PROTEIN)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		4 / 6 ARG A 115
THR A  57
ALA A  53
ARG A 174
 None
 1.40A 2ql8A-5mzoA:
undetectable
2ql8B-5mzoA:
undetectable		 2ql8A-5mzoA:
7.03
2ql8B-5mzoA:
7.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_F_CSCF1383_2
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		3 / 3 LEU A1399
MET A1403
MET A1329
 None
 0.87A 2vavF-5mzoA:
undetectable		 2vavF-5mzoA:
15.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_A_P1ZA1351_1
(PROSTAGLANDIN
REDUCTASE 2)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		5 / 10 TYR A 212
TYR A  61
LEU A  49
VAL A  46
LEU A  45
 None
 1.27A 2w98A-5mzoA:
undetectable		 2w98A-5mzoA:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEY_A_EV1A1771_1
(CAMP AND
CAMP-INHIBITED CGMP
3', 5'-CYCLIC
PHOSPHODIESTERASE)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		5 / 12 LEU A 792
VAL A 810
ILE A 675
TYR A 676
MET A 683
 None
 1.29A 2weyA-5mzoA:
undetectable		 2weyA-5mzoA:
12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEY_A_EV1A1771_1
(CAMP AND
CAMP-INHIBITED CGMP
3', 5'-CYCLIC
PHOSPHODIESTERASE)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		5 / 12 VAL A 810
ILE A 675
TYR A 676
GLU A 678
MET A 683
 None
 1.24A 2weyA-5mzoA:
undetectable		 2weyA-5mzoA:
12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWC_B_SAMB501_0
(SPERMIDINE SYNTHASE)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		5 / 12 LEU A  35
TYR A 962
ILE A1039
VAL A1004
GLY A1131
 None
 0.97A 3bwcB-5mzoA:
undetectable		 3bwcB-5mzoA:
11.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		6 / 12 LEU A 431
GLN A 580
ILE A 511
VAL A 472
VAL A 483
LEU A 533
 None
 1.29A 3gwxB-5mzoA:
undetectable		 3gwxB-5mzoA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEC_A_65BA561_0
(P66 REVERSE
TRANSCRIPTASE)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		5 / 12 LEU A 533
VAL A 516
TYR A 518
LEU A 474
PRO A 545
 None
 1.29A 3mecA-5mzoA:
2.8		 3mecA-5mzoA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S7S_A_EXMA601_1
(CYTOCHROME P450 19A1)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		5 / 9 ARG A 833
ILE A 837
ALA A 859
VAL A 731
LEU A 806
 None
 1.37A 3s7sA-5mzoA:
undetectable		 3s7sA-5mzoA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_2
(SECRETED ASPARTIC
PROTEASE)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		4 / 6 PRO A 503
SER A 536
TYR A 532
VAL A 516
 None
 0.85A 3tneA-5mzoA:
undetectable		 3tneA-5mzoA:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_C_ACTC502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		3 / 3 PRO A 561
ASP A 562
GLU A 565
 None
 0.89A 3v4tC-5mzoA:
undetectable		 3v4tC-5mzoA:
14.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		4 / 8 ASP A 421
ASP A 417
ASP A 464
ARG A 498
 None
 1.12A 4gkhF-5mzoA:
undetectable		 4gkhF-5mzoA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_E_CAME502_0
(CAMPHOR
5-MONOOXYGENASE)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		4 / 5 TYR A 122
THR A 169
PHE A 172
ILE A 184
 None
 1.23A 4jx1E-5mzoA:
undetectable		 4jx1E-5mzoA:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_M_ACTM503_0
(RNA POLYMERASE
3D-POL)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		4 / 4 PHE A1326
HIS A1357
GLY A1325
ILE A1409
 None
 1.40A 4k50M-5mzoA:
undetectable		 4k50M-5mzoA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KM2_A_TOPA202_1
(DIHYDROFOLATE
REDUCTASE)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		5 / 12 ILE A1200
ASP A1310
LEU A1412
LEU A1361
ILE A1299
 None
 1.04A 4km2A-5mzoA:
undetectable		 4km2A-5mzoA:
7.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KMM_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		4 / 5 MET A1214
LEU A1210
ARG A1449
SER A1204
 None
 1.35A 4kmmB-5mzoA:
undetectable		 4kmmB-5mzoA:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M6T_A_SAMA201_0
(RNA POLYMERASE
II-ASSOCIATED FACTOR
1 HOMOLOG, LINKER,
RNA
POLYMERASE-ASSOCIATE
D PROTEIN LEO1)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		4 / 4 ILE A 461
VAL A 497
VAL A 465
ARG A 463
 None
 1.33A 4m6tA-5mzoA:
undetectable		 4m6tA-5mzoA:
8.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM6_A_29EA603_1
(TRANSPORTER)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		5 / 12 VAL A 517
ALA A 529
TYR A 532
VAL A 480
SER A 536
 None
 1.28A 4mm6A-5mzoA:
undetectable		 4mm6A-5mzoA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM8_A_RFXA603_1
(TRANSPORTER)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		5 / 12 VAL A1289
TYR A1263
GLY A1056
GLY A1375
THR A1072
 None
 1.19A 4mm8A-5mzoA:
undetectable		 4mm8A-5mzoA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA603_1
(SERUM ALBUMIN)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		5 / 11 LEU A1285
SER A1386
LEU A1385
LEU A1269
LEU A1395
 None
 1.42A 4or0A-5mzoA:
undetectable		 4or0A-5mzoA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WA5_A_ZMRA501_1
(NEURAMINIDASE)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		5 / 12 ASP A 165
GLU A1064
GLU A1123
ARG A 215
TYR A 122
 None
 1.35A 4wa5A-5mzoA:
undetectable		 4wa5A-5mzoA:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_2
(ESTROGEN RECEPTOR)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		4 / 6 LEU A 811
LEU A 717
PHE A 828
LEU A 703
 None
 0.95A 5gs4A-5mzoA:
undetectable		 5gs4A-5mzoA:
10.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GTR_A_ESTA601_2
(ESTROGEN RECEPTOR)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		4 / 5 LEU A 811
LEU A 717
PHE A 828
LEU A 703
 None
 1.05A 5gtrA-5mzoA:
undetectable		 5gtrA-5mzoA:
10.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_0
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		5 / 12 VAL A 865
LEU A 849
GLY A 391
ALA A 394
LEU A 398
 None
 1.26A 5iktB-5mzoA:
undetectable		 5iktB-5mzoA:
16.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA609_0
(NADH DEHYDROGENASE,
PUTATIVE)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		3 / 3 VAL A 427
SER A 584
TRP A 587
 None
 0.77A 5jwaA-5mzoA:
undetectable		 5jwaA-5mzoA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KXI_A_NCTA402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		4 / 8 TYR A1282
TRP A1265
TYR A1263
LEU A1269
 None
 1.29A 5kxiA-5mzoA:
undetectable
5kxiB-5mzoA:
undetectable		 5kxiA-5mzoA:
14.40
5kxiB-5mzoA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_A_ACTA703_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		4 / 6 ARG A 110
ALA A 112
PRO A 114
PHE A1129
 EDO  A1615 (-2.9A)
None
None
None
 1.34A 5odqA-5mzoA:
undetectable		 5odqA-5mzoA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YK2_A_ERYA501_0
(PROBABLE CONSERVED
ATP-BINDING PROTEIN
ABC TRANSPORTER)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		5 / 11 GLU A1371
GLY A1375
ASP A1376
ALA A1374
ILE A1073
 None
 1.09A 5yk2A-5mzoA:
1.4		 5yk2A-5mzoA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_1
(SERUM ALBUMIN)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		4 / 5 ASN A  32
TYR A 232
VAL A1004
LEU A1036
 None
 1.04A 6a7pA-5mzoA:
undetectable		 6a7pA-5mzoA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRX_A_H8GA1201_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		5 / 12 SER A  41
PHE A1129
ALA A  37
ASN A 230
VAL A 976
 EDO  A1615 (-2.1A)
None
None
None
EDO  A1615 ( 4.7A)
 1.02A 6drxA-5mzoA:
undetectable		 6drxA-5mzoA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E8Q_A_X2NA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5mzo UDP-GLUCOSE-GLYCOPRO
TEIN
GLUCOSYLTRANSFERASE-
LIKE PROTEIN
(Chaetomium
thermophilum) 		4 / 4 TYR A1324
LEU A1351
TYR A1346
PRO A1355
 None
 1.43A 6e8qA-5mzoA:
0.1		 6e8qA-5mzoA:
5.11