SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5mzv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1001_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5mzv NANOBODY 22E11
(Lama
glama) 		4 / 6 SER D  54
ARG D  52
PRO D  58
GLY D  56
 None
 1.42A 2y7pA-5mzvD:
undetectable		 2y7pA-5mzvD:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_3
(NS3 PROTEASE, NS4A
PROTEIN)		 5mzv NANOBODY 22E11
(Lama
glama) 		4 / 5 SER D  85
ARG D  87
PRO D  88
VAL D 121
 None
 1.04A 3sufC-5mzvD:
undetectable		 3sufC-5mzvD:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_1
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 5mzv NANOBODY 22E11
(Lama
glama) 		3 / 3 ASP D  66
ARG D  67
ASP D  62
 None
 0.79A 4fzvA-5mzvD:
undetectable		 4fzvA-5mzvD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5mzv NANOBODY 22E11
(Lama
glama) 		4 / 7 ALA D  92
THR D  91
VAL D 119
GLU D  89
 None
 0.74A 5ecmD-5mzvD:
undetectable		 5ecmD-5mzvD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5mzv NANOBODY 22E11
(Lama
glama) 		4 / 7 ALA D  92
THR D  91
VAL D 119
GLU D  89
 None
 0.84A 5ecoD-5mzvD:
undetectable		 5ecoD-5mzvD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 5mzv NANOBODY 22E11
(Lama
glama) 		3 / 3 ASP D  66
ARG D  67
ASP D  62
 None
 0.63A 5zvgA-5mzvD:
undetectable		 5zvgA-5mzvD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 5mzv NANOBODY 22E11
(Lama
glama) 		3 / 3 ASP D  66
ARG D  67
ASP D  62
 None
 0.69A 5zvgB-5mzvD:
undetectable		 5zvgB-5mzvD:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CLX_A_SAMA401_0
(O-METHYLTRANSFERASE)		 5mzv NANOBODY 22E11
(Lama
glama) 		5 / 12 ALA D  24
GLY D  35
GLY D  97
SER D 105
VAL D  79
 None
 1.27A 6clxA-5mzvD:
undetectable		 6clxA-5mzvD:
undetectable