SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5n03'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DM6_A_IMNA1401_1
(NADP-DEPENDENT
LEUKOTRIENE B4
12-HYDROXYDEHYDROGEN
ASE)		 5n03 GLUTACONATE
COA-TRANSFERASE
FAMILY, SUBUNIT B
(Myxococcus
xanthus) 		5 / 10 ILE D  37
ALA D  36
ILE D 231
PRO D  65
ILE D 234
 None
 1.26A 2dm6A-5n03D:
6.0
2dm6B-5n03D:
6.3		 2dm6A-5n03D:
23.94
2dm6B-5n03D:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_A_ACTA653_0
(ACETYL-COENZYME A
SYNTHETASE)		 5n03 GLUTACONATE
COA-TRANSFERASE
FAMILY, SUBUNIT B
(Myxococcus
xanthus) 		4 / 5 VAL D 163
THR D 165
VAL D 132
GLY D 131
 None
 1.01A 2p2fA-5n03D:
4.4		 2p2fA-5n03D:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P2F_B_ACTB653_0
(ACETYL-COENZYME A
SYNTHETASE)		 5n03 GLUTACONATE
COA-TRANSFERASE
FAMILY, SUBUNIT B
(Myxococcus
xanthus) 		4 / 4 VAL D 163
THR D 165
VAL D 132
GLY D 131
 None
 0.99A 2p2fB-5n03D:
2.9		 2p2fB-5n03D:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_A_BEZA1162_0
(PEROXIREDOXIN-5)		 5n03 GLUTACONATE
COA-TRANSFERASE
FAMILY, SUBUNIT B
(Myxococcus
xanthus) 		5 / 10 PRO D  65
PRO D  62
GLY D  79
LEU D  68
GLY D  75
 None
 1.19A 2vl2A-5n03D:
undetectable
2vl2C-5n03D:
undetectable		 2vl2A-5n03D:
21.77
2vl2C-5n03D:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_B_CHDB1_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5n03 GLUTACONATE
COA-TRANSFERASE
FAMILY, SUBUNIT B
(Myxococcus
xanthus) 		4 / 4 LEU D  35
PRO D  34
LEU D 243
ARG D 151
 None
 1.34A 3hcoB-5n03D:
undetectable		 3hcoB-5n03D:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5n03 GLUTACONATE
COA-TRANSFERASE
FAMILY, SUBUNIT B
(Myxococcus
xanthus) 		5 / 12 LEU D  77
TYR D  76
GLY D  58
SER D  59
ALA D  32
 None
 1.27A 3ou6C-5n03D:
undetectable		 3ou6C-5n03D:
25.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5n03 GLUTACONATE
COA-TRANSFERASE
FAMILY, SUBUNIT B
(Myxococcus
xanthus) 		5 / 12 LEU D  77
TYR D  76
GLY D  58
SER D  59
ALA D  32
 None
 1.26A 3ou7C-5n03D:
2.2		 3ou7C-5n03D:
25.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OZK_A_T44A128_1
(TRANSTHYRETIN)		 5n03 GLUTACONATE
COA-TRANSFERASE
FAMILY, SUBUNIT B
(Myxococcus
xanthus) 		5 / 9 LEU D 148
THR D 100
SER D  33
THR D  29
VAL D  27
 None
 1.49A 3ozkA-5n03D:
undetectable		 3ozkA-5n03D:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P73_A_ACTA275_0
(MHC RFP-Y CLASS I
ALPHA CHAIN)		 5n03 GLUTACONATE
COA-TRANSFERASE
FAMILY, SUBUNIT B
(Myxococcus
xanthus) 		3 / 3 ILE D   7
VAL D 228
ARG D 232
 None
 0.59A 3p73A-5n03D:
undetectable		 3p73A-5n03D:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5n03 GLUTACONATE
COA-TRANSFERASE
FAMILY, SUBUNIT B
(Myxococcus
xanthus) 		4 / 5 PRO D  62
ASP D  61
ILE D  40
VAL D  98
 None
 1.01A 4hytA-5n03D:
undetectable		 4hytA-5n03D:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)		 5n03 GLUTACONATE
COA-TRANSFERASE
FAMILY, SUBUNIT B
(Myxococcus
xanthus) 		5 / 8 LEU D 148
THR D 100
SER D  33
THR D  29
VAL D  27
 None
 1.40A 4ik7B-5n03D:
undetectable		 4ik7B-5n03D:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_2
(ADENOSINE KINASE)		 5n03 GLUTACONATE
COA-TRANSFERASE
FAMILY, SUBUNIT B
(Myxococcus
xanthus) 		4 / 4 LEU D 148
SER D 177
LEU D  16
LEU D  35
 None
 0.88A 4n09A-5n03D:
3.4		 4n09A-5n03D:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 5n03 GLUTACONATE
COA-TRANSFERASE
FAMILY, SUBUNIT B
(Myxococcus
xanthus) 		4 / 7 SER D  70
ARG D  80
GLY D  58
GLU D  83
 None
 0.85A 5btaA-5n03D:
undetectable
5btaC-5n03D:
undetectable
5btaD-5n03D:
undetectable		 5btaA-5n03D:
21.53
5btaC-5n03D:
21.53
5btaD-5n03D:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 5n03 GLUTACONATE
COA-TRANSFERASE
FAMILY, SUBUNIT B
(Myxococcus
xanthus) 		4 / 6 SER D  70
ARG D  80
GLY D  58
GLU D  83
 None
 0.81A 5btaA-5n03D:
undetectable
5btaB-5n03D:
undetectable
5btaC-5n03D:
undetectable		 5btaA-5n03D:
21.53
5btaB-5n03D:
23.61
5btaC-5n03D:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 5n03 GLUTACONATE
COA-TRANSFERASE
FAMILY, SUBUNIT B
(Myxococcus
xanthus) 		4 / 6 SER D  70
ARG D  80
GLY D  58
GLU D  83
 None
 0.90A 5btcA-5n03D:
undetectable
5btcC-5n03D:
undetectable
5btcD-5n03D:
undetectable		 5btcA-5n03D:
21.53
5btcC-5n03D:
21.53
5btcD-5n03D:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 5n03 GLUTACONATE
COA-TRANSFERASE
FAMILY, SUBUNIT B
(Myxococcus
xanthus) 		4 / 6 SER D  70
ARG D  80
GLY D  58
GLU D  83
 None
 0.90A 5btcA-5n03D:
undetectable
5btcB-5n03D:
undetectable
5btcC-5n03D:
undetectable		 5btcA-5n03D:
21.53
5btcB-5n03D:
23.61
5btcC-5n03D:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_F_GFNF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 5n03 GLUTACONATE
COA-TRANSFERASE
FAMILY, SUBUNIT B
(Myxococcus
xanthus) 		4 / 7 SER D  70
ARG D  80
GLY D  58
GLU D  83
 None
 0.88A 5btfA-5n03D:
undetectable
5btfB-5n03D:
undetectable
5btfC-5n03D:
undetectable		 5btfA-5n03D:
21.53
5btfB-5n03D:
23.61
5btfC-5n03D:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_E_MFXE2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 5n03 GLUTACONATE
COA-TRANSFERASE
FAMILY, SUBUNIT B
(Myxococcus
xanthus) 		4 / 5 SER D  70
ARG D  80
GLY D  58
GLU D  83
 None
 1.12A 5cdqA-5n03D:
undetectable
5cdqB-5n03D:
undetectable
5cdqC-5n03D:
undetectable		 5cdqA-5n03D:
21.19
5cdqB-5n03D:
21.65
5cdqC-5n03D:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_V_MFXV2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 5n03 GLUTACONATE
COA-TRANSFERASE
FAMILY, SUBUNIT B
(Myxococcus
xanthus) 		4 / 5 SER D  70
ARG D  80
GLY D  58
GLU D  83
 None
 1.11A 5cdqR-5n03D:
undetectable
5cdqS-5n03D:
undetectable
5cdqT-5n03D:
undetectable		 5cdqR-5n03D:
21.19
5cdqS-5n03D:
21.65
5cdqT-5n03D:
21.19