SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5n05'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_D_DVAD8_0
(GRAMICIDIN A)		 5n05 AUXILIARY ACTIVITY 9
(Lentinus
similis) 		3 / 3 TRP A   8
VAL A   4
TRP A   5
 None
None
CL  A 314 (-4.7A)
 1.37A 1gmkC-5n05A:
undetectable
1gmkD-5n05A:
undetectable		 1gmkC-5n05A:
6.63
1gmkD-5n05A:
6.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7H_B_SAMB530_1
(TYPE I RESTRICTION
ENZYME ECOKI M
PROTEIN)		 5n05 AUXILIARY ACTIVITY 9
(Lentinus
similis) 		3 / 3 TYR A  85
GLU A 142
THR A 195
 None
 1.01A 2y7hB-5n05A:
undetectable		 2y7hB-5n05A:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_A_H3PA552_1
(GLUTAMATE
DEHYDROGENASE)		 5n05 AUXILIARY ACTIVITY 9
(Lentinus
similis) 		4 / 6 ILE A  82
TYR A  85
ILE A 144
HIS A  78
 None
None
None
CU  A 301 ( 3.2A)
 1.12A 3eteA-5n05A:
undetectable
3eteE-5n05A:
undetectable		 3eteA-5n05A:
18.04
3eteE-5n05A:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC554_1
(GLUTAMATE
DEHYDROGENASE)		 5n05 AUXILIARY ACTIVITY 9
(Lentinus
similis) 		4 / 5 ILE A  82
TYR A  85
ILE A 144
HIS A  78
 None
None
None
CU  A 301 ( 3.2A)
 1.11A 3eteB-5n05A:
undetectable
3eteC-5n05A:
undetectable		 3eteB-5n05A:
18.04
3eteC-5n05A:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_F_H3PF552_1
(GLUTAMATE
DEHYDROGENASE)		 5n05 AUXILIARY ACTIVITY 9
(Lentinus
similis) 		4 / 7 ILE A 144
HIS A  78
ILE A  82
TYR A  85
 None
CU  A 301 ( 3.2A)
None
None
 1.12A 3eteD-5n05A:
undetectable
3eteF-5n05A:
undetectable		 3eteD-5n05A:
18.04
3eteF-5n05A:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5n05 AUXILIARY ACTIVITY 9
(Lentinus
similis) 		3 / 3 GLY A  15
ASP A  13
ASP A 231
 CL  A 311 (-3.4A)
None
None
 0.47A 3ou7C-5n05A:
undetectable		 3ou7C-5n05A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOR_A_FLPA711_1
(LACTOTRANSFERRIN)		 5n05 AUXILIARY ACTIVITY 9
(Lentinus
similis) 		4 / 7 GLY A  57
VAL A 128
PRO A 130
GLY A 220
 None
 0.66A 4forA-5n05A:
undetectable		 4forA-5n05A:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GBO_A_CUA301_0
(E7)		 5n05 AUXILIARY ACTIVITY 9
(Lentinus
similis) 		4 / 5 ALA A  75
HIS A  78
GLN A 162
TYR A 164
 BGC  A 305 (-3.6A)
CU  A 301 ( 3.2A)
CL  A 309 (-3.3A)
HIC  A   1 (-3.9A)
 0.77A 4gboA-5n05A:
7.7		 4gboA-5n05A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GBO_B_CUB301_0
(E7)		 5n05 AUXILIARY ACTIVITY 9
(Lentinus
similis) 		4 / 5 ALA A  75
HIS A  78
GLN A 162
TYR A 164
 BGC  A 305 (-3.6A)
CU  A 301 ( 3.2A)
CL  A 309 (-3.3A)
HIC  A   1 (-3.9A)
 1.06A 4gboB-5n05A:
7.8		 4gboB-5n05A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_A_ASCA303_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 5n05 AUXILIARY ACTIVITY 9
(Lentinus
similis) 		4 / 7 PHE A 102
HIS A 125
ILE A  82
ASN A 107
 None
 1.35A 4o7gA-5n05A:
undetectable
4o7gB-5n05A:
undetectable		 4o7gA-5n05A:
21.76
4o7gB-5n05A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O7G_B_ASCB304_0
(PROBABLE
TRANSMEMBRANE
ASCORBATE
FERRIREDUCTASE 2)		 5n05 AUXILIARY ACTIVITY 9
(Lentinus
similis) 		4 / 6 PHE A 102
HIS A 125
ILE A  82
ASN A 107
 None
 1.42A 4o7gB-5n05A:
undetectable		 4o7gB-5n05A:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_D_PARD500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 5n05 AUXILIARY ACTIVITY 9
(Lentinus
similis) 		4 / 8 SER A 219
THR A 179
ASP A 176
ASP A 177
 None
None
CL  A 313 (-3.4A)
None
 1.20A 4qb9D-5n05A:
undetectable		 4qb9D-5n05A:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA301_0
(THAUMATIN-1)		 5n05 AUXILIARY ACTIVITY 9
(Lentinus
similis) 		3 / 3 THR A 109
ASN A 110
SER A 111
 None
 0.73A 4tvtA-5n05A:
undetectable		 4tvtA-5n05A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_B_SAMB601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 5n05 AUXILIARY ACTIVITY 9
(Lentinus
similis) 		5 / 12 ILE A 170
VAL A   7
TRP A   8
VAL A   9
VAL A  54
 None
 1.04A 5dpdB-5n05A:
undetectable		 5dpdB-5n05A:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UIZ_A_CUA301_0
(AA10A)		 5n05 AUXILIARY ACTIVITY 9
(Lentinus
similis) 		4 / 5 ALA A  75
HIS A  78
GLN A 162
TYR A 164
 BGC  A 305 (-3.6A)
CU  A 301 ( 3.2A)
CL  A 309 (-3.3A)
HIC  A   1 (-3.9A)
 0.73A 5uizA-5n05A:
7.8		 5uizA-5n05A:
20.32