SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5n07'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD8_0
(GRAMICIDIN A)		 5n07 HTH-TYPE
TRANSCRIPTIONAL
REPRESSOR NSRR
(Streptomyces
coelicolor) 		3 / 3 VAL A  75
VAL A  77
TRP A  79
 None
 0.88A 1av2C-5n07A:
undetectable
1av2D-5n07A:
undetectable		 1av2C-5n07A:
8.73
1av2D-5n07A:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_D_DVAD8_0
(GRAMICIDIN D)		 5n07 HTH-TYPE
TRANSCRIPTIONAL
REPRESSOR NSRR
(Streptomyces
coelicolor) 		3 / 3 VAL A  75
VAL A  77
TRP A  79
 None
 0.84A 1w5uC-5n07A:
undetectable
1w5uD-5n07A:
undetectable		 1w5uC-5n07A:
8.73
1w5uD-5n07A:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_D_SALD5006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5n07 HTH-TYPE
TRANSCRIPTIONAL
REPRESSOR NSRR
(Streptomyces
coelicolor) 		4 / 5 ARG A  73
THR A 128
LEU A 130
ALA A  18
 None
 1.03A 2e1qD-5n07A:
undetectable		 2e1qD-5n07A:
8.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA8_0
(GRAMICIDIN D)		 5n07 HTH-TYPE
TRANSCRIPTIONAL
REPRESSOR NSRR
(Streptomyces
coelicolor) 		3 / 3 VAL A  77
TRP A  79
VAL A  75
 None
 0.80A 2izqA-5n07A:
undetectable
2izqB-5n07A:
undetectable		 2izqA-5n07A:
8.73
2izqB-5n07A:
8.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD8_0
(GRAMICIDIN D)		 5n07 HTH-TYPE
TRANSCRIPTIONAL
REPRESSOR NSRR
(Streptomyces
coelicolor) 		3 / 3 VAL A  75
VAL A  77
TRP A  79
 None
 0.83A 3l8lC-5n07A:
undetectable
3l8lD-5n07A:
undetectable		 3l8lC-5n07A:
8.73
3l8lD-5n07A:
9.52