SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5n0c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_A_TESA325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		4 / 7 LEU A 216
TYR A 909
THR A 624
ASN A 792
 None
 1.18A 1afsA-5n0cA:
undetectable		 1afsA-5n0cA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AFS_B_TESB325_1
(3-ALPHA-HYDROXYSTERO
ID DEHYDROGENASE)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		4 / 7 LEU A 216
TYR A 909
THR A 624
ASN A 792
 None
 1.18A 1afsB-5n0cA:
undetectable		 1afsB-5n0cA:
13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPK_A_ACAA80_1
(PLASMINOGEN)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		4 / 6 PRO A1212
ASP A1147
ASN A1144
TYR A1229
 None
 1.48A 1hpkA-5n0cA:
undetectable		 1hpkA-5n0cA:
4.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I1E_A_DM2A3001_1
(BOTULINUM NEUROTOXIN
TYPE B)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		5 / 9 GLY A1269
HIS A1271
SER A1287
TRP A1289
TYR A1290
 None
GAL  A1404 ( 4.2A)
NGA  A1403 ( 3.7A)
GAL  A1404 ( 3.9A)
GAL  A1404 (-4.4A)
 0.73A 1i1eA-5n0cA:
52.6		 1i1eA-5n0cA:
41.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M4I_A_KANA500_1
(AMINOGLYCOSIDE
2'-N-ACETYLTRANSFERA
SE)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		4 / 8 ASP A 406
GLY A 413
THR A 217
ASP A 894
 None
 0.91A 1m4iA-5n0cA:
undetectable		 1m4iA-5n0cA:
8.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_A_THAA1_1
(LIVER
CARBOXYLESTERASE I)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		5 / 11 LEU A1198
PHE A1175
GLY A1210
LEU A1257
LEU A1255
 None
 1.11A 1mx1A-5n0cA:
undetectable		 1mx1A-5n0cA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VM1_A_TAZA504_1
(BETA-LACTAMASE SHV-1)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		3 / 3 ASP A1125
TYR A1124
GLU A1185
 None
 0.85A 1vm1A-5n0cA:
undetectable		 1vm1A-5n0cA:
11.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_2
(CES1 PROTEIN)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		4 / 4 LEU A 889
PRO A 910
ILE A 934
LEU A1072
 None
 1.09A 1ya4B-5n0cA:
undetectable		 1ya4B-5n0cA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_2
(CES1 PROTEIN)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		4 / 4 LEU A 889
PRO A 910
ILE A 934
LEU A1072
 None
 1.06A 1ya4C-5n0cA:
undetectable		 1ya4C-5n0cA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_A_NFZA1219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		4 / 8 TYR A 657
ASN A 660
GLU A 666
GLY A 663
 None
 1.01A 1ykiA-5n0cA:
undetectable
1ykiB-5n0cA:
undetectable		 1ykiA-5n0cA:
8.99
1ykiB-5n0cA:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_B_NFZB2219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		4 / 8 TYR A 657
ASN A 660
GLU A 666
GLY A 663
 None
 1.01A 1ykiA-5n0cA:
undetectable
1ykiB-5n0cA:
undetectable		 1ykiA-5n0cA:
8.99
1ykiB-5n0cA:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_C_NFZC3219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		4 / 8 TYR A 657
ASN A 660
GLU A 666
GLY A 663
 None
 0.98A 1ykiC-5n0cA:
undetectable
1ykiD-5n0cA:
undetectable		 1ykiC-5n0cA:
8.99
1ykiD-5n0cA:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_D_NFZD4219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		4 / 8 TYR A 657
ASN A 660
GLU A 666
GLY A 663
 None
 1.01A 1ykiC-5n0cA:
undetectable
1ykiD-5n0cA:
undetectable		 1ykiC-5n0cA:
8.99
1ykiD-5n0cA:
8.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		4 / 5 ILE A 934
ILE A 218
ILE A 791
LEU A 914
 None
 0.94A 1zgyA-5n0cA:
undetectable		 1zgyA-5n0cA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A8T_B_ADNB252_1
(U8 SNORNA-BINDING
PROTEIN X29)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		4 / 8 GLY A 173
THR A 155
ILE A 174
SER A 192
 None
 1.03A 2a8tB-5n0cA:
undetectable		 2a8tB-5n0cA:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		4 / 7 LEU A1255
GLN A1254
LEU A1198
PHE A1175
 None
 1.09A 2eimC-5n0cA:
2.7
2eimJ-5n0cA:
undetectable		 2eimC-5n0cA:
10.63
2eimJ-5n0cA:
3.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		4 / 6 LEU A1255
GLN A1254
LEU A1198
PHE A1175
 None
 1.12A 2einP-5n0cA:
3.1
2einW-5n0cA:
undetectable		 2einP-5n0cA:
10.63
2einW-5n0cA:
3.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA2_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		4 / 6 ILE A 793
ILE A 934
TYR A 909
LEU A 745
 None
 1.14A 3adsA-5n0cA:
undetectable		 3adsA-5n0cA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H5G_A_LEIA16_0
(COIL SER L16D-PEN)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		4 / 6 GLN A 968
LEU A 966
GLU A 967
LEU A1162
 None
 0.85A 3h5gA-5n0cA:
undetectable
3h5gC-5n0cA:
undetectable		 3h5gA-5n0cA:
2.19
3h5gC-5n0cA:
2.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_B_HAEB271_1
(COLLAGENASE 3)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		3 / 3 HIS A 233
GLU A 234
HIS A 237
 ZN  A1406 (-3.5A)
ZN  A1406 ( 4.4A)
ZN  A1406 (-3.4A)
 0.15A 3kecB-5n0cA:
undetectable		 3kecB-5n0cA:
7.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_1
(PROTEASE)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		5 / 9 ASP A 634
ILE A 633
ILE A 795
VAL A 670
ILE A 636
 None
 1.00A 3nu4A-5n0cA:
undetectable		 3nu4A-5n0cA:
5.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_1
(N-METHYLTRANSFERASE)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		3 / 3 TYR A 542
TYR A  73
GLU A 170
 None
 0.87A 3pfgA-5n0cA:
undetectable		 3pfgA-5n0cA:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQW_I_ACHI323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		4 / 8 ILE A 369
TYR A 394
LEU A 388
PHE A 400
 None
 1.04A 3rqwI-5n0cA:
undetectable
3rqwJ-5n0cA:
undetectable		 3rqwI-5n0cA:
13.26
3rqwJ-5n0cA:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA503_1
(CYTOCHROME P450 2B4)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		5 / 11 ILE A  43
ILE A  98
PHE A 198
ILE A 159
VAL A 238
 None
 0.94A 3tmzA-5n0cA:
1.2		 3tmzA-5n0cA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA503_1
(CYTOCHROME P450 2B4)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		5 / 11 ILE A  98
PHE A 198
ILE A 159
ALA A 228
VAL A 238
 None
 0.97A 3tmzA-5n0cA:
1.2		 3tmzA-5n0cA:
17.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_2
(SECRETED ASPARTIC
PROTEASE)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		4 / 7 SER A 377
TYR A 739
ILE A 210
THR A 732
 None
 1.07A 3tneB-5n0cA:
undetectable		 3tneB-5n0cA:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA5_B_06XB501_1
(CYTOCHROME P450 2B6)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		4 / 7 ILE A 704
GLU A 713
LEU A 688
VAL A 494
 None
 0.85A 3ua5B-5n0cA:
undetectable		 3ua5B-5n0cA:
16.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7H_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		3 / 3 ARG A 528
THR A 155
TRP A  44
 None
 0.95A 4d7hA-5n0cA:
undetectable		 4d7hA-5n0cA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJW_A_SRYA2001_2
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		4 / 6 GLU A 746
ASN A 787
GLU A 410
VAL A 418
 None
 1.07A 4ejwB-5n0cA:
undetectable		 4ejwB-5n0cA:
8.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_B_ASWB1301_1
(DNA TOPOISOMERASE
2-BETA)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		4 / 7 ILE A 253
PRO A 254
GLY A  68
GLU A  67
 None
 0.65A 4g0uB-5n0cA:
2.6		 4g0uB-5n0cA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		5 / 12 GLN A1082
ASN A1078
LEU A1074
ILE A 976
LEU A1000
 None
 1.24A 4k36A-5n0cA:
undetectable		 4k36A-5n0cA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		5 / 12 GLN A1082
ASN A1078
LEU A1074
ILE A 976
LEU A1000
 None
 1.18A 4k36B-5n0cA:
undetectable		 4k36B-5n0cA:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KJK_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		5 / 12 ILE A  39
PHE A  95
ILE A 111
LEU A 235
ILE A  43
 None
 1.09A 4kjkA-5n0cA:
undetectable		 4kjkA-5n0cA:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LHM_A_AZZA510_1
(THYMIDINE
PHOSPHORYLASE)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		5 / 11 LEU A 745
TYR A 645
VAL A 643
MET A 797
LEU A 673
 None
 1.19A 4lhmA-5n0cA:
undetectable		 4lhmA-5n0cA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LHM_A_AZZA510_1
(THYMIDINE
PHOSPHORYLASE)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		5 / 11 LEU A 745
VAL A 643
ILE A 646
MET A 797
LEU A 673
 None
 1.41A 4lhmA-5n0cA:
undetectable		 4lhmA-5n0cA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		4 / 8 GLU A 973
GLN A1013
ILE A1014
LEU A1004
 None
 0.80A 4mj8A-5n0cA:
undetectable		 4mj8A-5n0cA:
9.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UG5_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		3 / 3 ARG A 528
THR A 155
TRP A  44
 None
 0.96A 4ug5A-5n0cA:
undetectable		 4ug5A-5n0cA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGL_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		3 / 3 ARG A 528
THR A 155
TRP A  44
 None
 0.97A 4uglA-5n0cA:
undetectable		 4uglA-5n0cA:
13.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_LZUA3008_1
(ALDEHYDE OXIDASE)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		4 / 8 GLU A 819
ASP A 821
SER A 824
ARG A 711
 None
 1.19A 4uhxA-5n0cA:
2.5		 4uhxA-5n0cA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHX_A_RTZA3009_1
(ALDEHYDE OXIDASE)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		4 / 8 GLU A 819
ASP A 821
SER A 824
ARG A 711
 None
 1.19A 4uhxA-5n0cA:
2.5		 4uhxA-5n0cA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UY8_7_TRP71002_0
(TRYPTOPHANASE)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		4 / 4 ILE A1070
ASN A1069
ILE A 907
VAL A 906
 None
 0.84A 4uy87-5n0cA:
undetectable		 4uy87-5n0cA:
3.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHQ_A_SAMA301_0
(CATECHOL
O-METHYLTRANSFERASE)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		5 / 12 VAL A 426
TYR A  72
ASN A 472
HIS A 380
ASP A 207
 None
 1.21A 5fhqA-5n0cA:
undetectable		 5fhqA-5n0cA:
10.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6C_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		3 / 3 ARG A 528
THR A 155
TRP A  44
 None
 0.95A 5g6cA-5n0cA:
undetectable		 5g6cA-5n0cA:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HIE_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		4 / 7 ILE A 918
GLY A 917
ASP A1116
PHE A1305
 None
 1.09A 5hieA-5n0cA:
undetectable		 5hieA-5n0cA:
12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB603_1
(PHIAB6 TAILSPIKE)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		3 / 3 VAL A 494
GLU A 717
GLU A 713
 None
 0.94A 5jsdB-5n0cA:
undetectable
5jsdC-5n0cA:
undetectable		 5jsdB-5n0cA:
21.67
5jsdC-5n0cA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_B_SAMB1304_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		3 / 3 ASN A 138
TYR A  33
CYH A  27
 None
 1.03A 5lsuB-5n0cA:
undetectable		 5lsuB-5n0cA:
12.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_E_PFLE406_1
(PROTON-GATED ION
CHANNEL)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		5 / 10 TYR A 516
ILE A  98
ILE A 111
ILE A 112
ILE A  43
 None
 1.09A 5murE-5n0cA:
undetectable		 5murE-5n0cA:
6.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		4 / 8 ILE A 218
TYR A 909
THR A 908
ILE A 907
 None
 0.94A 5mzrE-5n0cA:
3.1		 5mzrE-5n0cA:
6.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		4 / 5 TYR A  72
TYR A  73
GLY A 430
GLY A 428
 None
 1.09A 5x7pA-5n0cA:
undetectable		 5x7pA-5n0cA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
7DFR_A_FOLA161_0
(DIHYDROFOLATE
REDUCTASE)		 5n0c TETANUS TOXIN
(Clostridium
tetani) 		5 / 12 ILE A  39
PHE A  95
ILE A 111
LEU A 235
ILE A  43
 None
 1.09A 7dfrA-5n0cA:
undetectable		 7dfrA-5n0cA:
8.25