SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5n0g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BCU_H_PRLH280_0
(ALPHA-THROMBIN)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		5 / 9 ASP A  76
ALA A  77
GLU A  82
CYH A  75
GLY A 135
 None
 1.25A 1bcuH-5n0gA:
undetectable		 1bcuH-5n0gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		6 / 12 ILE A  73
ALA A  71
ALA A 130
LEU A  67
ALA A  66
VAL A  80
 None
 1.25A 1fbyA-5n0gA:
undetectable		 1fbyA-5n0gA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBY_B_9CRB1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		6 / 12 ILE A  73
ALA A  71
ALA A 130
LEU A  67
ALA A  66
VAL A  80
 None
 1.21A 1fbyB-5n0gA:
undetectable		 1fbyB-5n0gA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_A_9CRA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		5 / 12 ILE A  73
ALA A  71
ALA A 130
LEU A  67
ALA A  66
 None
 0.92A 1fm6A-5n0gA:
undetectable		 1fm6A-5n0gA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		6 / 12 ILE A  73
ALA A  71
ALA A 130
LEU A  67
ALA A  66
VAL A  80
 None
 1.21A 1fm9A-5n0gA:
undetectable		 1fm9A-5n0gA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		6 / 12 ILE A  73
ALA A  71
ALA A 130
LEU A  67
ALA A  66
VAL A  80
 None
 1.23A 1k74A-5n0gA:
undetectable		 1k74A-5n0gA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KI7_B_ID2B2_0
(THYMIDINE KINASE)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		5 / 12 GLU A 209
ILE A  20
ILE A  41
ALA A 199
ARG A  21
 None
None
None
8F5  A 301 (-4.0A)
None
 1.25A 1ki7B-5n0gA:
undetectable		 1ki7B-5n0gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_E_9CRE1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		6 / 12 ILE A  73
ALA A  71
ALA A 130
LEU A  67
ALA A  66
VAL A  80
 None
 1.20A 1xdkE-5n0gA:
undetectable		 1xdkE-5n0gA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_A_9CRA201_1
(RXR-LIKE PROTEIN)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		6 / 12 ILE A  73
ALA A  71
ALA A 130
LEU A  67
ALA A  66
VAL A  80
 None
 1.20A 1xiuA-5n0gA:
undetectable		 1xiuA-5n0gA:
16.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_A_9CRA801_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		5 / 12 ILE A  73
ALA A  71
ALA A 130
LEU A  67
ALA A  66
 None
 0.91A 1xlsA-5n0gA:
undetectable		 1xlsA-5n0gA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_B_9CRB802_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		5 / 12 ILE A  73
ALA A  71
ALA A 130
LEU A  67
ALA A  66
 None
 0.91A 1xlsB-5n0gA:
undetectable		 1xlsB-5n0gA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_C_9CRC803_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		5 / 12 ILE A  73
ALA A  71
ALA A 130
LEU A  67
ALA A  66
 None
 0.91A 1xlsC-5n0gA:
undetectable		 1xlsC-5n0gA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLS_D_9CRD804_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		5 / 12 ILE A  73
ALA A  71
ALA A 130
LEU A  67
ALA A  66
 None
 0.91A 1xlsD-5n0gA:
undetectable		 1xlsD-5n0gA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_A_REAA502_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		5 / 12 ALA A  44
ALA A  43
ASN A 202
LEU A  49
ILE A 160
 None
8F5  A 301 ( 4.1A)
8F5  A 301 (-3.8A)
None
None
 0.98A 2aclA-5n0gA:
undetectable
2aclE-5n0gA:
undetectable		 2aclA-5n0gA:
18.03
2aclE-5n0gA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_C_REAC503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		5 / 10 ILE A 196
ALA A  44
ALA A  43
ASN A 202
ILE A 160
 None
None
8F5  A 301 ( 4.1A)
8F5  A 301 (-3.8A)
None
 1.07A 2aclC-5n0gA:
undetectable		 2aclC-5n0gA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_E_REAE504_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		5 / 11 ILE A 196
ALA A  44
ALA A  43
ASN A 202
ILE A 160
 None
None
8F5  A 301 ( 4.1A)
8F5  A 301 (-3.8A)
None
 1.11A 2aclE-5n0gA:
undetectable		 2aclE-5n0gA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACL_G_REAG501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		5 / 12 ILE A  73
ALA A  71
ALA A 130
LEU A  67
ALA A  66
 None
 0.97A 2aclG-5n0gA:
undetectable		 2aclG-5n0gA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FAL_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		5 / 10 ILE A  73
ALA A  71
ALA A 130
LEU A  67
ALA A  66
 None
 0.92A 3falC-5n0gA:
undetectable		 3falC-5n0gA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FAL_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		5 / 10 ILE A  73
ALA A  71
LEU A  89
ALA A  91
ILE A 160
 None
 1.01A 3falC-5n0gA:
undetectable		 3falC-5n0gA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FAL_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		5 / 10 ILE A 196
ALA A  44
ALA A  43
LEU A  49
ILE A 160
 None
None
8F5  A 301 ( 4.1A)
None
None
 0.87A 3falC-5n0gA:
undetectable		 3falC-5n0gA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC6_A_REAA501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		5 / 11 ILE A  73
ALA A  71
ALA A 130
LEU A  67
ALA A  66
 None
 0.93A 3fc6A-5n0gA:
undetectable		 3fc6A-5n0gA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJX_B_HCZB800_1
(GLUTAMATE RECEPTOR 2)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		5 / 10 PRO A 138
SER A 116
ILE A 134
PRO A 163
GLY A 135
 None
 1.15A 3ijxB-5n0gA:
undetectable
3ijxD-5n0gA:
undetectable		 3ijxB-5n0gA:
15.42
3ijxD-5n0gA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_B_HFZB800_1
(GLUTAMATE RECEPTOR 2)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		5 / 10 PRO A 138
SER A 116
ILE A 134
PRO A 163
GLY A 135
 None
 1.10A 3iluB-5n0gA:
undetectable
3iluE-5n0gA:
undetectable		 3iluB-5n0gA:
15.42
3iluE-5n0gA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_E_HFZE800_1
(GLUTAMATE RECEPTOR 2)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		5 / 11 ILE A 134
PRO A 163
GLY A 135
PRO A 138
SER A 116
 None
 1.13A 3iluB-5n0gA:
undetectable
3iluE-5n0gA:
undetectable		 3iluB-5n0gA:
15.42
3iluE-5n0gA:
15.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_A_ADNA300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		5 / 11 VAL A  53
ILE A 160
GLY A 161
THR A 197
ALA A 200
 None
 0.79A 3kw2A-5n0gA:
2.8		 3kw2A-5n0gA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_B_ADNB300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		5 / 11 VAL A  53
ILE A 160
GLY A 161
THR A 197
ALA A 200
 None
 0.73A 3kw2B-5n0gA:
undetectable		 3kw2B-5n0gA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RD0_A_EDPA175_1
(FERRITIN LIGHT CHAIN)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		4 / 6 LEU A 176
SER A 172
ALA A 169
LEU A 145
 None
 1.02A 3rd0A-5n0gA:
undetectable		 3rd0A-5n0gA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		5 / 12 ALA A  71
ALA A 130
ILE A 159
LEU A  67
ALA A  66
 None
 1.01A 4k6iA-5n0gA:
undetectable		 4k6iA-5n0gA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		5 / 12 ILE A  73
ALA A  71
ALA A 130
LEU A  67
ALA A  66
 None
 0.86A 4k6iA-5n0gA:
undetectable		 4k6iA-5n0gA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QDJ_A_SAMA301_0
(MAGNESIUM-PROTOPORPH
YRIN
O-METHYLTRANSFERASE)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		5 / 12 VAL A 201
GLY A 135
GLY A 193
ILE A 160
VAL A  80
 None
 0.85A 4qdjA-5n0gA:
2.2		 4qdjA-5n0gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_1
(PROTEIN CYP51)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		5 / 12 ALA A 119
ALA A  56
ALA A 177
LEU A 145
MET A 147
 None
 1.08A 5tl8A-5n0gA:
undetectable		 5tl8A-5n0gA:
10.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_A_9CRA503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		6 / 12 ILE A  73
ALA A  71
ALA A 130
LEU A  67
ALA A  66
VAL A  80
 None
 1.25A 5uanA-5n0gA:
undetectable		 5uanA-5n0gA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		6 / 12 ILE A  73
ALA A  71
ALA A 130
LEU A  67
ALA A  66
VAL A  80
 None
 1.18A 5z12B-5n0gA:
undetectable		 5z12B-5n0gA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_C_9CRC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		6 / 12 ILE A  73
ALA A  71
ALA A 130
LEU A  67
ALA A  66
VAL A  80
 None
 1.15A 5z12C-5n0gA:
undetectable		 5z12C-5n0gA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		5 / 12 ILE A  73
ALA A  71
ALA A 130
LEU A  67
ALA A  66
 None
 0.91A 6a5yD-5n0gA:
undetectable		 6a5yD-5n0gA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Y_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		5 / 12 ILE A 196
ALA A  44
ALA A  43
LEU A  49
ILE A 160
 None
None
8F5  A 301 ( 4.1A)
None
None
 0.80A 6a5yD-5n0gA:
undetectable		 6a5yD-5n0gA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		5 / 12 ILE A  73
ALA A  71
ALA A 130
LEU A  67
ALA A  66
 None
 0.96A 6a5zD-5n0gA:
undetectable		 6a5zD-5n0gA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_L_9CRL501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		5 / 12 ILE A  73
ALA A  71
ALA A 130
LEU A  67
ALA A  66
 None
 0.95A 6a5zL-5n0gA:
undetectable		 6a5zL-5n0gA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_L_9CRL501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		5 / 12 ILE A 196
ALA A  44
ALA A  43
LEU A  49
ILE A 160
 None
None
8F5  A 301 ( 4.1A)
None
None
 0.90A 6a5zL-5n0gA:
undetectable		 6a5zL-5n0gA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_1
(CYTOCHROME P450 1A1)		 5n0g PRECORRIN-8X
METHYLMUTASE
(Rhodobacter
capsulatus) 		4 / 7 GLY A 129
ALA A 130
VAL A 201
LEU A  67
 None
 0.82A 6dwnB-5n0gA:
undetectable		 6dwnB-5n0gA:
16.28