SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5n0o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_A_BZMA600_0
(ODORANT-BINDING
PROTEIN)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		4 / 8 ILE A 114
MET A  83
ASN A 106
LEU A  12
 None
 0.70A 1dzmA-5n0oA:
undetectable		 1dzmA-5n0oA:
16.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P73_A_ACTA275_0
(MHC RFP-Y CLASS I
ALPHA CHAIN)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		3 / 3 ILE A 114
VAL A  84
ARG A  88
 None
None
EDO  A 503 (-4.0A)
 0.56A 3p73A-5n0oA:
undetectable		 3p73A-5n0oA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_2
(HIV-1 PROTEASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		5 / 12 LEU A 125
VAL A  96
ILE A  52
THR A  13
VAL A  15
 None
 0.87A 3so9B-5n0oA:
undetectable		 3so9B-5n0oA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		4 / 6 HIS A 100
HIS A 109
SER A 108
ASP A  45
 None
 1.38A 4blvA-5n0oA:
undetectable		 4blvA-5n0oA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N0O_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		6 / 12 ILE A  19
GLY A  18
SER A 129
TYR A 211
ALA A 213
VAL A 243
 SAM  A 501 (-4.5A)
None
SAM  A 501 (-4.7A)
SAM  A 501 (-4.7A)
SAM  A 501 (-3.6A)
SAM  A 501 (-4.0A)
 1.04A 5n0oA-5n0oA:
50.1		 5n0oA-5n0oA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N0O_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		12 / 12 ILE A  19
TYR A  98
GLY A  99
HIS A 100
VAL A 103
PHE A 104
VAL A 105
SER A 129
PHE A 171
TYR A 211
ALA A 213
VAL A 243
 SAM  A 501 (-4.5A)
SAM  A 501 (-4.7A)
SAM  A 501 (-3.5A)
None
SAM  A 501 (-4.4A)
None
None
SAM  A 501 (-4.7A)
SAM  A 501 (-4.3A)
SAM  A 501 (-4.7A)
SAM  A 501 (-3.6A)
SAM  A 501 (-4.0A)
 0.00A 5n0oA-5n0oA:
50.1		 5n0oA-5n0oA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N0O_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		3 / 3 ALA A 130
GLN A 172
THR A 245
 SAM  A 501 (-3.2A)
HSE  A 504 ( 3.3A)
SAM  A 501 (-3.6A)
 0.04A 5n0oA-5n0oA:
50.1		 5n0oA-5n0oA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N0O_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		7 / 12 ILE A  19
GLY A  18
SER A 129
ALA A 130
TYR A 211
ALA A 213
VAL A 243
 SAM  A 501 (-4.5A)
None
SAM  A 501 (-4.7A)
SAM  A 501 (-3.2A)
SAM  A 501 (-4.7A)
SAM  A 501 (-3.6A)
SAM  A 501 (-4.0A)
 0.98A 5n0oB-5n0oA:
46.0		 5n0oB-5n0oA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N0O_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		12 / 12 ILE A  19
TYR A  98
GLY A  99
HIS A 100
PHE A 104
VAL A 105
SER A 129
ALA A 130
PHE A 171
TYR A 211
ALA A 213
VAL A 243
 SAM  A 501 (-4.5A)
SAM  A 501 (-4.7A)
SAM  A 501 (-3.5A)
None
None
None
SAM  A 501 (-4.7A)
SAM  A 501 (-3.2A)
SAM  A 501 (-4.3A)
SAM  A 501 (-4.7A)
SAM  A 501 (-3.6A)
SAM  A 501 (-4.0A)
 0.07A 5n0oB-5n0oA:
46.0		 5n0oB-5n0oA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N0R_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		5 / 12 ILE A  19
GLY A  18
TYR A 211
ALA A 213
VAL A 243
 SAM  A 501 (-4.5A)
None
SAM  A 501 (-4.7A)
SAM  A 501 (-3.6A)
SAM  A 501 (-4.0A)
 0.93A 5n0rA-5n0oA:
45.3		 5n0rA-5n0oA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N0R_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		11 / 12 ILE A  19
TYR A  98
GLY A  99
HIS A 100
VAL A 103
PHE A 104
VAL A 105
PHE A 171
TYR A 211
ALA A 213
VAL A 243
 SAM  A 501 (-4.5A)
SAM  A 501 (-4.7A)
SAM  A 501 (-3.5A)
None
SAM  A 501 (-4.4A)
None
None
SAM  A 501 (-4.3A)
SAM  A 501 (-4.7A)
SAM  A 501 (-3.6A)
SAM  A 501 (-4.0A)
 0.10A 5n0rA-5n0oA:
45.3		 5n0rA-5n0oA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N0R_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		7 / 12 ILE A  19
TYR A  98
GLY A  99
HIS A 100
VAL A 103
VAL A 105
MET A 215
 SAM  A 501 (-4.5A)
SAM  A 501 (-4.7A)
SAM  A 501 (-3.5A)
None
SAM  A 501 (-4.4A)
None
None
 0.70A 5n0rA-5n0oA:
45.3		 5n0rA-5n0oA:
99.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		4 / 4 SER A 129
ALA A 130
GLN A 172
THR A 245
 SAM  A 501 (-4.7A)
SAM  A 501 (-3.2A)
HSE  A 504 ( 3.3A)
SAM  A 501 (-3.6A)
 0.12A 5n0rA-5n0oA:
45.3		 5n0rA-5n0oA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N0S_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		6 / 12 ILE A  19
GLY A  18
TYR A 211
ILE A 212
ALA A 213
VAL A 243
 SAM  A 501 (-4.5A)
None
SAM  A 501 (-4.7A)
SAM  A 501 (-4.7A)
SAM  A 501 (-3.6A)
SAM  A 501 (-4.0A)
 0.81A 5n0sA-5n0oA:
43.8		 5n0sA-5n0oA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N0S_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		11 / 12 ILE A  19
GLY A  99
HIS A 100
VAL A 103
PHE A 104
VAL A 105
PHE A 171
TYR A 211
ILE A 212
ALA A 213
VAL A 243
 SAM  A 501 (-4.5A)
SAM  A 501 (-3.5A)
None
SAM  A 501 (-4.4A)
None
None
SAM  A 501 (-4.3A)
SAM  A 501 (-4.7A)
SAM  A 501 (-4.7A)
SAM  A 501 (-3.6A)
SAM  A 501 (-4.0A)
 0.17A 5n0sA-5n0oA:
43.8		 5n0sA-5n0oA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N0S_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		5 / 12 ILE A  19
GLY A  99
HIS A 100
VAL A 105
MET A 215
 SAM  A 501 (-4.5A)
SAM  A 501 (-3.5A)
None
None
None
 0.85A 5n0sA-5n0oA:
43.8		 5n0sA-5n0oA:
99.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		4 / 4 SER A 129
ALA A 130
GLN A 172
THR A 245
 SAM  A 501 (-4.7A)
SAM  A 501 (-3.2A)
HSE  A 504 ( 3.3A)
SAM  A 501 (-3.6A)
 0.10A 5n0sA-5n0oA:
43.8		 5n0sA-5n0oA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N0S_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		12 / 12 ILE A  19
HIS A 100
VAL A 103
PHE A 104
VAL A 105
SER A 129
PHE A 171
GLN A 172
TYR A 211
ILE A 212
ALA A 213
VAL A 243
 SAM  A 501 (-4.5A)
None
SAM  A 501 (-4.4A)
None
None
SAM  A 501 (-4.7A)
SAM  A 501 (-4.3A)
HSE  A 504 ( 3.3A)
SAM  A 501 (-4.7A)
SAM  A 501 (-4.7A)
SAM  A 501 (-3.6A)
SAM  A 501 (-4.0A)
 0.24A 5n0sB-5n0oA:
21.8		 5n0sB-5n0oA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N0T_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		6 / 12 ILE A  19
GLY A  18
TYR A 211
ILE A 212
ALA A 213
VAL A 243
 SAM  A 501 (-4.5A)
None
SAM  A 501 (-4.7A)
SAM  A 501 (-4.7A)
SAM  A 501 (-3.6A)
SAM  A 501 (-4.0A)
 0.87A 5n0tA-5n0oA:
22.4		 5n0tA-5n0oA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N0T_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		11 / 12 ILE A  19
GLY A  99
HIS A 100
VAL A 103
PHE A 104
VAL A 105
PHE A 171
TYR A 211
ILE A 212
ALA A 213
VAL A 243
 SAM  A 501 (-4.5A)
SAM  A 501 (-3.5A)
None
SAM  A 501 (-4.4A)
None
None
SAM  A 501 (-4.3A)
SAM  A 501 (-4.7A)
SAM  A 501 (-4.7A)
SAM  A 501 (-3.6A)
SAM  A 501 (-4.0A)
 0.17A 5n0tA-5n0oA:
22.4		 5n0tA-5n0oA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N0T_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		6 / 12 ILE A  19
GLY A  99
HIS A 100
VAL A 103
VAL A 105
MET A 215
 SAM  A 501 (-4.5A)
SAM  A 501 (-3.5A)
None
SAM  A 501 (-4.4A)
None
None
 0.76A 5n0tA-5n0oA:
22.4		 5n0tA-5n0oA:
99.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		4 / 5 SER A 129
ALA A 130
GLN A 172
THR A 245
 SAM  A 501 (-4.7A)
SAM  A 501 (-3.2A)
HSE  A 504 ( 3.3A)
SAM  A 501 (-3.6A)
 0.14A 5n0tA-5n0oA:
22.4		 5n0tA-5n0oA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		4 / 5 TYR A  98
SER A 129
ALA A 130
THR A 245
 SAM  A 501 (-4.7A)
SAM  A 501 (-4.7A)
SAM  A 501 (-3.2A)
SAM  A 501 (-3.6A)
 0.84A 5n0tA-5n0oA:
22.4		 5n0tA-5n0oA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N0T_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		7 / 12 ILE A  19
GLY A  18
ALA A 130
TYR A 211
ILE A 212
ALA A 213
VAL A 243
 SAM  A 501 (-4.5A)
None
SAM  A 501 (-3.2A)
SAM  A 501 (-4.7A)
SAM  A 501 (-4.7A)
SAM  A 501 (-3.6A)
SAM  A 501 (-4.0A)
 0.89A 5n0tB-5n0oA:
23.0		 5n0tB-5n0oA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N0T_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		11 / 12 ILE A  19
GLY A  99
HIS A 100
PHE A 104
VAL A 105
ALA A 130
PHE A 171
TYR A 211
ILE A 212
ALA A 213
VAL A 243
 SAM  A 501 (-4.5A)
SAM  A 501 (-3.5A)
None
None
None
SAM  A 501 (-3.2A)
SAM  A 501 (-4.3A)
SAM  A 501 (-4.7A)
SAM  A 501 (-4.7A)
SAM  A 501 (-3.6A)
SAM  A 501 (-4.0A)
 0.18A 5n0tB-5n0oA:
23.0		 5n0tB-5n0oA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N0T_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		5 / 12 ILE A  19
GLY A  99
HIS A 100
VAL A 105
MET A 215
 SAM  A 501 (-4.5A)
SAM  A 501 (-3.5A)
None
None
None
 0.87A 5n0tB-5n0oA:
23.0		 5n0tB-5n0oA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N0W_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		5 / 12 ILE A  19
GLY A  18
TYR A 211
ALA A 213
VAL A 243
 SAM  A 501 (-4.5A)
None
SAM  A 501 (-4.7A)
SAM  A 501 (-3.6A)
SAM  A 501 (-4.0A)
 0.90A 5n0wA-5n0oA:
43.8		 5n0wA-5n0oA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N0W_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		11 / 12 ILE A  19
TYR A  98
GLY A  99
HIS A 100
VAL A 103
PHE A 104
VAL A 105
PHE A 171
TYR A 211
ALA A 213
VAL A 243
 SAM  A 501 (-4.5A)
SAM  A 501 (-4.7A)
SAM  A 501 (-3.5A)
None
SAM  A 501 (-4.4A)
None
None
SAM  A 501 (-4.3A)
SAM  A 501 (-4.7A)
SAM  A 501 (-3.6A)
SAM  A 501 (-4.0A)
 0.08A 5n0wA-5n0oA:
43.8		 5n0wA-5n0oA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N0W_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		7 / 12 ILE A  19
TYR A  98
GLY A  99
HIS A 100
VAL A 103
VAL A 105
MET A 215
 SAM  A 501 (-4.5A)
SAM  A 501 (-4.7A)
SAM  A 501 (-3.5A)
None
SAM  A 501 (-4.4A)
None
None
 0.67A 5n0wA-5n0oA:
43.8		 5n0wA-5n0oA:
99.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		4 / 4 SER A 129
ALA A 130
GLN A 172
THR A 245
 SAM  A 501 (-4.7A)
SAM  A 501 (-3.2A)
HSE  A 504 ( 3.3A)
SAM  A 501 (-3.6A)
 0.11A 5n0wA-5n0oA:
43.8		 5n0wA-5n0oA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N0W_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		6 / 12 ILE A  19
GLY A  18
TYR A 211
ILE A 212
ALA A 213
VAL A 243
 SAM  A 501 (-4.5A)
None
SAM  A 501 (-4.7A)
SAM  A 501 (-4.7A)
SAM  A 501 (-3.6A)
SAM  A 501 (-4.0A)
 0.87A 5n0wB-5n0oA:
44.6		 5n0wB-5n0oA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N0W_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		11 / 12 ILE A  19
GLY A  99
HIS A 100
VAL A 103
PHE A 104
VAL A 105
PHE A 171
TYR A 211
ILE A 212
ALA A 213
VAL A 243
 SAM  A 501 (-4.5A)
SAM  A 501 (-3.5A)
None
SAM  A 501 (-4.4A)
None
None
SAM  A 501 (-4.3A)
SAM  A 501 (-4.7A)
SAM  A 501 (-4.7A)
SAM  A 501 (-3.6A)
SAM  A 501 (-4.0A)
 0.05A 5n0wB-5n0oA:
44.6		 5n0wB-5n0oA:
99.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N0W_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		6 / 12 ILE A  19
GLY A  99
HIS A 100
VAL A 103
VAL A 105
MET A 215
 SAM  A 501 (-4.5A)
SAM  A 501 (-3.5A)
None
SAM  A 501 (-4.4A)
None
None
 0.68A 5n0wB-5n0oA:
44.6		 5n0wB-5n0oA:
99.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		5 / 5 TYR A  98
SER A 129
ALA A 130
GLN A 172
THR A 245
 SAM  A 501 (-4.7A)
SAM  A 501 (-4.7A)
SAM  A 501 (-3.2A)
HSE  A 504 ( 3.3A)
SAM  A 501 (-3.6A)
 0.21A 5n0wB-5n0oA:
44.6		 5n0wB-5n0oA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N0X_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		6 / 12 ILE A  19
GLY A  18
TYR A 211
ILE A 212
ALA A 213
VAL A 243
 SAM  A 501 (-4.5A)
None
SAM  A 501 (-4.7A)
SAM  A 501 (-4.7A)
SAM  A 501 (-3.6A)
SAM  A 501 (-4.0A)
 0.88A 5n0xA-5n0oA:
45.3		 5n0xA-5n0oA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N0X_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		11 / 12 ILE A  19
TYR A  98
GLY A  99
HIS A 100
PHE A 104
VAL A 105
PHE A 171
TYR A 211
ILE A 212
ALA A 213
VAL A 243
 SAM  A 501 (-4.5A)
SAM  A 501 (-4.7A)
SAM  A 501 (-3.5A)
None
None
None
SAM  A 501 (-4.3A)
SAM  A 501 (-4.7A)
SAM  A 501 (-4.7A)
SAM  A 501 (-3.6A)
SAM  A 501 (-4.0A)
 0.03A 5n0xA-5n0oA:
45.3		 5n0xA-5n0oA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N0X_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		7 / 12 ILE A  19
TYR A  98
GLY A  99
HIS A 100
VAL A 105
ALA A 213
MET A 215
 SAM  A 501 (-4.5A)
SAM  A 501 (-4.7A)
SAM  A 501 (-3.5A)
None
None
SAM  A 501 (-3.6A)
None
 0.65A 5n0xA-5n0oA:
45.3		 5n0xA-5n0oA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		4 / 4 SER A 129
ALA A 130
GLN A 172
THR A 245
 SAM  A 501 (-4.7A)
SAM  A 501 (-3.2A)
HSE  A 504 ( 3.3A)
SAM  A 501 (-3.6A)
 0.11A 5n0xA-5n0oA:
45.3		 5n0xA-5n0oA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N0X_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		5 / 12 ILE A  19
GLY A  18
TYR A 211
ALA A 213
VAL A 243
 SAM  A 501 (-4.5A)
None
SAM  A 501 (-4.7A)
SAM  A 501 (-3.6A)
SAM  A 501 (-4.0A)
 0.91A 5n0xB-5n0oA:
45.7		 5n0xB-5n0oA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N0X_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		11 / 12 ILE A  19
TYR A  98
GLY A  99
HIS A 100
PHE A 104
VAL A 105
PHE A 171
GLN A 172
TYR A 211
ALA A 213
VAL A 243
 SAM  A 501 (-4.5A)
SAM  A 501 (-4.7A)
SAM  A 501 (-3.5A)
None
None
None
SAM  A 501 (-4.3A)
HSE  A 504 ( 3.3A)
SAM  A 501 (-4.7A)
SAM  A 501 (-3.6A)
SAM  A 501 (-4.0A)
 0.10A 5n0xB-5n0oA:
45.7		 5n0xB-5n0oA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N0X_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		8 / 12 ILE A  19
TYR A  98
GLY A  99
HIS A 100
VAL A 105
GLN A 172
ALA A 213
MET A 215
 SAM  A 501 (-4.5A)
SAM  A 501 (-4.7A)
SAM  A 501 (-3.5A)
None
None
HSE  A 504 ( 3.3A)
SAM  A 501 (-3.6A)
None
 0.61A 5n0xB-5n0oA:
45.7		 5n0xB-5n0oA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N0X_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		3 / 3 SER A 129
ALA A 130
THR A 245
 SAM  A 501 (-4.7A)
SAM  A 501 (-3.2A)
SAM  A 501 (-3.6A)
 0.00A 5n0xB-5n0oA:
45.7		 5n0xB-5n0oA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N4I_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		6 / 12 ILE A  19
GLY A  18
TYR A 211
ILE A 212
ALA A 213
VAL A 243
 SAM  A 501 (-4.5A)
None
SAM  A 501 (-4.7A)
SAM  A 501 (-4.7A)
SAM  A 501 (-3.6A)
SAM  A 501 (-4.0A)
 0.88A 5n4iA-5n0oA:
44.5		 5n4iA-5n0oA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N4I_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		11 / 12 ILE A  19
GLY A  99
HIS A 100
VAL A 103
PHE A 104
VAL A 105
PHE A 171
TYR A 211
ILE A 212
ALA A 213
VAL A 243
 SAM  A 501 (-4.5A)
SAM  A 501 (-3.5A)
None
SAM  A 501 (-4.4A)
None
None
SAM  A 501 (-4.3A)
SAM  A 501 (-4.7A)
SAM  A 501 (-4.7A)
SAM  A 501 (-3.6A)
SAM  A 501 (-4.0A)
 0.16A 5n4iA-5n0oA:
44.5		 5n4iA-5n0oA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N4I_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		6 / 12 ILE A  19
GLY A  99
HIS A 100
VAL A 103
VAL A 105
MET A 215
 SAM  A 501 (-4.5A)
SAM  A 501 (-3.5A)
None
SAM  A 501 (-4.4A)
None
None
 0.68A 5n4iA-5n0oA:
44.5		 5n4iA-5n0oA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		5 / 5 TYR A  98
SER A 129
ALA A 130
GLN A 172
THR A 245
 SAM  A 501 (-4.7A)
SAM  A 501 (-4.7A)
SAM  A 501 (-3.2A)
HSE  A 504 ( 3.3A)
SAM  A 501 (-3.6A)
 0.19A 5n4iA-5n0oA:
44.5		 5n4iA-5n0oA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V02_R_657R201_0
(CALMODULIN-1
SMALL CONDUCTANCE
CALCIUM-ACTIVATED
POTASSIUM CHANNEL
PROTEIN 2)		 5n0o PEPTIDE
N-METHYLTRANSFERASE
(Omphalotus
olearius) 		5 / 10 LEU A 194
VAL A 195
LEU A 170
VAL A 208
ILE A 248
 None
 1.07A 5v02B-5n0oA:
undetectable
5v02R-5n0oA:
undetectable		 5v02B-5n0oA:
undetectable
5v02R-5n0oA:
undetectable