SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5n11'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKO_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 5n11 HEMAGGLUTININ-ESTERA
SE
(Betacoronavirus
1) 		5 / 10 LEU A 253
VAL A 230
TYR A 232
TYR A 223
LEU A 193
 None
 1.44A 1fkoA-5n11A:
undetectable		 1fkoA-5n11A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZVJ_A_SAMA301_0
(CATECHOL
O-METHYLTRANSFERASE)		 5n11 HEMAGGLUTININ-ESTERA
SE
(Betacoronavirus
1) 		5 / 12 GLU A 101
GLY A 102
TYR A  88
TRP A 292
ARG A 291
 None
None
None
None
NAG  A 511 (-3.8A)
 1.42A 2zvjA-5n11A:
undetectable		 2zvjA-5n11A:
19.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_1
(UNCHARACTERIZED
PROTEIN MJ1557)		 5n11 HEMAGGLUTININ-ESTERA
SE
(Betacoronavirus
1) 		3 / 3 MET A 137
GLU A 101
ASN A  76
 None
 0.81A 3a27A-5n11A:
undetectable		 3a27A-5n11A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWY_A_SAMA301_0
(COMT PROTEIN)		 5n11 HEMAGGLUTININ-ESTERA
SE
(Betacoronavirus
1) 		5 / 12 GLU A 101
GLY A 102
TYR A  88
TRP A 292
ARG A 291
 None
None
None
None
NAG  A 511 (-3.8A)
 1.42A 3bwyA-5n11A:
undetectable		 3bwyA-5n11A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GV1_B_BEZB301_0
(DISULFIDE
INTERCHANGE PROTEIN)		 5n11 HEMAGGLUTININ-ESTERA
SE
(Betacoronavirus
1) 		4 / 6 LEU A 193
ALA A 273
PRO A 202
PRO A 270
 None
 1.35A 3gv1A-5n11A:
undetectable
3gv1B-5n11A:
undetectable		 3gv1A-5n11A:
15.93
3gv1B-5n11A:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD392_1
(TETX2 PROTEIN)		 5n11 HEMAGGLUTININ-ESTERA
SE
(Betacoronavirus
1) 		4 / 5 HIS A  29
SER A  28
SER A 338
VAL A  26
 None
 1.49A 4a99D-5n11A:
undetectable		 4a99D-5n11A:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_B_SAMB900_1
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 5n11 HEMAGGLUTININ-ESTERA
SE
(Betacoronavirus
1) 		4 / 4 ILE A 336
SER A 338
ASP A 330
ASP A 325
 None
 1.32A 4krhB-5n11A:
undetectable		 4krhB-5n11A:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_B_STRB601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5n11 HEMAGGLUTININ-ESTERA
SE
(Betacoronavirus
1) 		4 / 5 ILE A 175
LEU A 267
ASP A 190
VAL A 201
 None
None
NAG  A 508 (-3.3A)
None
 0.91A 4nkxB-5n11A:
undetectable		 4nkxB-5n11A:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_0
(PROLINE--TRNA LIGASE)		 5n11 HEMAGGLUTININ-ESTERA
SE
(Betacoronavirus
1) 		5 / 12 VAL A 361
PRO A  23
THR A  24
SER A 335
GLY A 339
 None
 1.48A 4ydqB-5n11A:
undetectable		 4ydqB-5n11A:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 5n11 HEMAGGLUTININ-ESTERA
SE
(Betacoronavirus
1) 		3 / 3 GLY A 332
ASP A 330
ASN A 327
 None
 0.38A 5jglA-5n11A:
undetectable		 5jglA-5n11A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_A_LLLA301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5n11 HEMAGGLUTININ-ESTERA
SE
(Betacoronavirus
1) 		4 / 6 ASP A 281
TYR A 367
ASP A  33
GLU A  93
 None
 1.36A 6mn5A-5n11A:
undetectable		 6mn5A-5n11A:
13.33