SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5n13'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_A_NFZA1219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5n13 BROMODOMAIN-CONTAINI
NG FACTOR 1
(Candida
albicans) 		4 / 8 TYR A 465
PHE A 467
ASN A 468
PHE A 411
 None
None
GOL  A 501 (-3.1A)
GOL  A 501 (-4.8A)
 1.03A 1ykiA-5n13A:
undetectable
1ykiB-5n13A:
undetectable		 1ykiA-5n13A:
23.35
1ykiB-5n13A:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_B_NFZB2219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5n13 BROMODOMAIN-CONTAINI
NG FACTOR 1
(Candida
albicans) 		4 / 8 PHE A 411
TYR A 465
PHE A 467
ASN A 468
 GOL  A 501 (-4.8A)
None
None
GOL  A 501 (-3.1A)
 1.03A 1ykiA-5n13A:
undetectable
1ykiB-5n13A:
undetectable		 1ykiA-5n13A:
23.35
1ykiB-5n13A:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_C_NFZC3219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5n13 BROMODOMAIN-CONTAINI
NG FACTOR 1
(Candida
albicans) 		4 / 8 TYR A 465
PHE A 467
ASN A 468
PHE A 411
 None
None
GOL  A 501 (-3.1A)
GOL  A 501 (-4.8A)
 1.02A 1ykiC-5n13A:
undetectable
1ykiD-5n13A:
undetectable		 1ykiC-5n13A:
23.35
1ykiD-5n13A:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_D_NFZD4219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5n13 BROMODOMAIN-CONTAINI
NG FACTOR 1
(Candida
albicans) 		4 / 8 PHE A 411
TYR A 465
PHE A 467
ASN A 468
 GOL  A 501 (-4.8A)
None
None
GOL  A 501 (-3.1A)
 0.99A 1ykiC-5n13A:
undetectable
1ykiD-5n13A:
undetectable		 1ykiC-5n13A:
23.35
1ykiD-5n13A:
23.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_C_08JC3_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5n13 BROMODOMAIN-CONTAINI
NG FACTOR 1
(Candida
albicans) 		4 / 8 PRO A 410
VAL A 415
LEU A 420
MET A 477
 GOL  A 502 (-4.4A)
GOL  A 502 ( 4.0A)
GOL  A 501 ( 4.9A)
None
 0.93A 3u5kC-5n13A:
16.0		 3u5kC-5n13A:
36.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A9K_A_TYLA2200_1
(CREB-BINDING PROTEIN)		 5n13 BROMODOMAIN-CONTAINI
NG FACTOR 1
(Candida
albicans) 		4 / 6 VAL A 415
ILE A 422
ASN A 468
VAL A 474
 GOL  A 502 ( 4.0A)
None
GOL  A 501 (-3.1A)
None
 0.59A 4a9kA-5n13A:
16.7		 4a9kA-5n13A:
33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A9K_B_TYLB2198_1
(CREB-BINDING PROTEIN)		 5n13 BROMODOMAIN-CONTAINI
NG FACTOR 1
(Candida
albicans) 		4 / 5 VAL A 415
ILE A 422
ASN A 468
VAL A 474
 GOL  A 502 ( 4.0A)
None
GOL  A 501 (-3.1A)
None
 0.63A 4a9kB-5n13A:
17.1		 4a9kB-5n13A:
33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_C_SAMC601_1
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 5n13 BROMODOMAIN-CONTAINI
NG FACTOR 1
(Candida
albicans) 		4 / 5 ALA A 413
ASP A 434
MET A 433
ASN A 408
 GOL  A 502 (-3.6A)
None
None
None
 1.43A 4obwC-5n13A:
undetectable		 4obwC-5n13A:
14.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5PBE_A_TYLA2001_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 5n13 BROMODOMAIN-CONTAINI
NG FACTOR 1
(Candida
albicans) 		4 / 6 PRO A 410
VAL A 415
TYR A 425
ASN A 468
 GOL  A 502 (-4.4A)
GOL  A 502 ( 4.0A)
GOL  A 501 ( 4.9A)
GOL  A 501 (-3.1A)
 0.57A 5pbeA-5n13A:
16.5		 5pbeA-5n13A:
31.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH8_A_ACTA302_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5n13 BROMODOMAIN-CONTAINI
NG FACTOR 1
(Candida
albicans) 		3 / 3 CYH A 392
MET A 384
ASN A 449
 None
 1.38A 5qh8A-5n13A:
undetectable		 5qh8A-5n13A:
20.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Y1Y_A_HNQA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5n13 BROMODOMAIN-CONTAINI
NG FACTOR 1
(Candida
albicans) 		4 / 8 VAL A 415
LEU A 420
CYH A 464
ASN A 468
 GOL  A 502 ( 4.0A)
GOL  A 501 ( 4.9A)
GOL  A 501 (-4.1A)
GOL  A 501 (-3.1A)
 0.65A 5y1yA-5n13A:
16.3		 5y1yA-5n13A:
36.36