SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5n15'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5J_A_08HA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5n15 BROMODOMAIN-CONTAINI
NG FACTOR 1
(Candida
albicans) 		5 / 7 PRO A 233
LEU A 243
ASN A 291
ILE A 297
MET A 300
 IOD  A 405 ( 4.4A)
None
IOD  A 404 (-3.9A)
IOD  A 404 ( 4.8A)
None
 0.66A 3u5jA-5n15A:
18.5		 3u5jA-5n15A:
35.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_A_08JA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5n15 BROMODOMAIN-CONTAINI
NG FACTOR 1
(Candida
albicans) 		5 / 8 PRO A 233
VAL A 238
ASN A 291
ILE A 297
MET A 300
 IOD  A 405 ( 4.4A)
None
IOD  A 404 (-3.9A)
IOD  A 404 ( 4.8A)
None
 0.40A 3u5kA-5n15A:
18.6		 3u5kA-5n15A:
35.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_A_08JA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5n15 BROMODOMAIN-CONTAINI
NG FACTOR 1
(Candida
albicans) 		4 / 8 PRO A 233
VAL A 238
LEU A 243
MET A 300
 IOD  A 405 ( 4.4A)
None
None
None
 0.53A 3u5kA-5n15A:
18.6		 3u5kA-5n15A:
35.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_B_08JB2_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5n15 BROMODOMAIN-CONTAINI
NG FACTOR 1
(Candida
albicans) 		4 / 7 PRO A 233
VAL A 238
ASN A 291
ILE A 297
 IOD  A 405 ( 4.4A)
None
IOD  A 404 (-3.9A)
IOD  A 404 ( 4.8A)
 0.25A 3u5kB-5n15A:
18.5		 3u5kB-5n15A:
35.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_B_08JB2_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5n15 BROMODOMAIN-CONTAINI
NG FACTOR 1
(Candida
albicans) 		4 / 7 PRO A 233
VAL A 238
LEU A 243
ILE A 297
 IOD  A 405 ( 4.4A)
None
None
IOD  A 404 ( 4.8A)
 0.58A 3u5kB-5n15A:
18.5		 3u5kB-5n15A:
35.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_C_08JC3_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5n15 BROMODOMAIN-CONTAINI
NG FACTOR 1
(Candida
albicans) 		5 / 8 PRO A 233
VAL A 238
ASN A 291
ILE A 297
MET A 300
 IOD  A 405 ( 4.4A)
None
IOD  A 404 (-3.9A)
IOD  A 404 ( 4.8A)
None
 0.39A 3u5kC-5n15A:
18.1		 3u5kC-5n15A:
35.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_C_08JC3_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5n15 BROMODOMAIN-CONTAINI
NG FACTOR 1
(Candida
albicans) 		5 / 8 PRO A 233
VAL A 238
LEU A 243
ILE A 297
MET A 300
 IOD  A 405 ( 4.4A)
None
None
IOD  A 404 ( 4.8A)
None
 0.56A 3u5kC-5n15A:
18.1		 3u5kC-5n15A:
35.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U5K_D_08JD4_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5n15 BROMODOMAIN-CONTAINI
NG FACTOR 1
(Candida
albicans) 		5 / 8 PRO A 233
VAL A 238
ASN A 291
ILE A 297
MET A 300
 IOD  A 405 ( 4.4A)
None
IOD  A 404 (-3.9A)
IOD  A 404 ( 4.8A)
None
 0.44A 3u5kD-5n15A:
18.2		 3u5kD-5n15A:
35.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A9J_A_TYLA1188_1
(BROMODOMAIN
CONTAINING 2)		 5n15 BROMODOMAIN-CONTAINI
NG FACTOR 1
(Candida
albicans) 		4 / 5 VAL A 238
LEU A 243
ASN A 291
ILE A 297
 None
None
IOD  A 404 (-3.9A)
IOD  A 404 ( 4.8A)
 0.41A 4a9jA-5n15A:
16.9		 4a9jA-5n15A:
31.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A9J_B_TYLB1187_1
(BROMODOMAIN
CONTAINING 2)		 5n15 BROMODOMAIN-CONTAINI
NG FACTOR 1
(Candida
albicans) 		4 / 5 VAL A 238
LEU A 243
ASN A 291
ILE A 297
 None
None
IOD  A 404 (-3.9A)
IOD  A 404 ( 4.8A)
 0.55A 4a9jB-5n15A:
17.1		 4a9jB-5n15A:
31.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A9J_C_TYLC1184_1
(BROMODOMAIN
CONTAINING 2)		 5n15 BROMODOMAIN-CONTAINI
NG FACTOR 1
(Candida
albicans) 		4 / 5 VAL A 238
LEU A 243
ASN A 291
ILE A 297
 None
None
IOD  A 404 (-3.9A)
IOD  A 404 ( 4.8A)
 0.62A 4a9jC-5n15A:
16.7		 4a9jC-5n15A:
31.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4C66_A_H4CA1168_0
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5n15 BROMODOMAIN-CONTAINI
NG FACTOR 1
(Candida
albicans) 		6 / 9 PRO A 233
VAL A 238
LEU A 243
ASN A 291
ILE A 297
MET A 300
 IOD  A 405 ( 4.4A)
None
None
IOD  A 404 (-3.9A)
IOD  A 404 ( 4.8A)
None
 0.55A 4c66A-5n15A:
18.4		 4c66A-5n15A:
36.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CUT_A_TYLA2971_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 5n15 BROMODOMAIN-CONTAINI
NG FACTOR 1
(Candida
albicans) 		4 / 4 VAL A 238
VAL A 245
ASN A 291
ILE A 297
 None
IOD  A 401 ( 4.1A)
IOD  A 404 (-3.9A)
IOD  A 404 ( 4.8A)
 0.83A 4cutA-5n15A:
14.6		 4cutA-5n15A:
28.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PBE_A_TYLA2001_1
(BROMODOMAIN ADJACENT
TO ZINC FINGER
DOMAIN PROTEIN 2B)		 5n15 BROMODOMAIN-CONTAINI
NG FACTOR 1
(Candida
albicans) 		6 / 6 PRO A 233
VAL A 238
VAL A 245
TYR A 248
ASN A 291
ILE A 297
 IOD  A 405 ( 4.4A)
None
IOD  A 401 ( 4.1A)
None
IOD  A 404 (-3.9A)
IOD  A 404 ( 4.8A)
 0.89A 5pbeA-5n15A:
14.6		 5pbeA-5n15A:
27.03
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Y1Y_A_HNQA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5n15 BROMODOMAIN-CONTAINI
NG FACTOR 1
(Candida
albicans) 		5 / 8 PRO A 233
VAL A 238
CYH A 287
ASN A 291
ILE A 297
 IOD  A 405 ( 4.4A)
None
IOD  A 404 ( 4.5A)
IOD  A 404 (-3.9A)
IOD  A 404 ( 4.8A)
 0.37A 5y1yA-5n15A:
18.5		 5y1yA-5n15A:
36.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Y1Y_A_HNQA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5n15 BROMODOMAIN-CONTAINI
NG FACTOR 1
(Candida
albicans) 		5 / 8 PRO A 233
VAL A 238
LEU A 243
CYH A 287
ILE A 297
 IOD  A 405 ( 4.4A)
None
None
IOD  A 404 ( 4.5A)
IOD  A 404 ( 4.8A)
 0.48A 5y1yA-5n15A:
18.5		 5y1yA-5n15A:
36.23
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Y1Y_A_HNQA201_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5n15 BROMODOMAIN-CONTAINI
NG FACTOR 1
(Candida
albicans) 		5 / 8 VAL A 238
LEU A 243
CYH A 287
ASN A 291
ILE A 297
 None
None
IOD  A 404 ( 4.5A)
IOD  A 404 (-3.9A)
IOD  A 404 ( 4.8A)
 1.11A 5y1yA-5n15A:
18.5		 5y1yA-5n15A:
36.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLO_A_GBQA1501_1
(SUBSTANCE-P
RECEPTOR,GLGA
GLYCOGEN
SYNTHASE,SUBSTANCE-P
RECEPTOR)		 5n15 BROMODOMAIN-CONTAINI
NG FACTOR 1
(Candida
albicans) 		5 / 9 ASN A 286
ILE A 261
GLU A 230
VAL A 225
ILE A 222
 None
 1.35A 6hloA-5n15A:
undetectable		 6hloA-5n15A:
13.71