SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5n1x'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_B_ADNB301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 5n1x B-CELL LYMPHOMA 6
PROTEIN
(Homo
sapiens) 		5 / 10 ALA D 109
GLY D  82
LEU D  97
ASN D 101
ILE D 102
 None
 1.03A 3wdmB-5n1xD:
undetectable		 3wdmB-5n1xD:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_C_ADNC301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 5n1x B-CELL LYMPHOMA 6
PROTEIN
(Homo
sapiens) 		5 / 9 ALA D 109
GLY D  82
LEU D  97
ASN D 101
ILE D 102
 None
 1.09A 3wdmC-5n1xD:
undetectable		 3wdmC-5n1xD:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_D_ADND301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 5n1x B-CELL LYMPHOMA 6
PROTEIN
(Homo
sapiens) 		5 / 10 ALA D 109
GLY D  82
LEU D  97
ASN D 101
ILE D 102
 None
 1.12A 3wdmD-5n1xD:
undetectable		 3wdmD-5n1xD:
18.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_A_ADNA301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 5n1x B-CELL LYMPHOMA 6
PROTEIN
(Homo
sapiens) 		5 / 9 PRO D  80
LEU D  86
ILE D  78
VAL D 105
THR D 108
 None
 1.15A 4x3mA-5n1xD:
undetectable		 4x3mA-5n1xD:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X3M_B_ADNB301_1
(RNA 2'-O RIBOSE
METHYLTRANSFERASE)		 5n1x B-CELL LYMPHOMA 6
PROTEIN
(Homo
sapiens) 		5 / 9 PRO D  80
LEU D  86
ILE D  78
VAL D 105
THR D 108
 None
 1.10A 4x3mB-5n1xD:
undetectable		 4x3mB-5n1xD:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5n1x B-CELL LYMPHOMA 6
PROTEIN
(Homo
sapiens) 		4 / 5 ILE D  72
PHE D  61
ARG D  26
THR D  32
 None
 1.30A 5z84N-5n1xD:
undetectable
5z84W-5n1xD:
undetectable		 5z84N-5n1xD:
14.18
5z84W-5n1xD:
19.30