SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5n22'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q2H_B_ACTB501_0
(SECRETION CHAPERONE,
PHAGE-DISPLAY
DERIVED PEPTIDE)		 5n22 XECO2
(Xenopus
laevis) 		3 / 3 ARG A 659
SER A 660
TYR A 689
 None
 0.93A 2q2hA-5n22A:
undetectable
2q2hB-5n22A:
undetectable		 2q2hA-5n22A:
22.46
2q2hB-5n22A:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_B_SAMB301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 5n22 XECO2
(Xenopus
laevis) 		5 / 12 ILE A 587
VAL A 581
ILE A 528
LEU A 591
VAL A 554
 None
 1.22A 3fpjB-5n22A:
undetectable		 3fpjB-5n22A:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NOO_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 5n22 XECO2
(Xenopus
laevis) 		4 / 6 TYR A 689
ASP A 681
GLY A 682
PHE A 675
 None
 1.05A 5nooC-5n22A:
undetectable		 5nooC-5n22A:
23.45