SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5n2b'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)
5n2b PUTATIVE FIMBRIAL
SUBUNIT TYPE 1

(Burkholderia
pseudomallei)
5 / 11 PHE A  35
ILE A 154
ALA A 118
LEU A 107
ALA A 167
None
1.24A 1jb0B-5n2bA:
undetectable
1jb0B-5n2bA:
8.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)
5n2b PUTATIVE FIMBRIAL
SUBUNIT TYPE 1

(Burkholderia
pseudomallei)
5 / 12 THR A 174
ALA A 172
SER A  89
GLY A  90
SER A 135
None
1.05A 3mg02-5n2bA:
undetectable
3mg0V-5n2bA:
undetectable
3mg02-5n2bA:
17.84
3mg0V-5n2bA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)
5n2b PUTATIVE FIMBRIAL
SUBUNIT TYPE 1

(Burkholderia
pseudomallei)
5 / 11 PHE A  35
ILE A 154
ALA A 118
LEU A 107
ALA A 167
None
1.24A 3pcqB-5n2bA:
undetectable
3pcqB-5n2bA:
8.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA302_1
(CHITOSANASE)
5n2b PUTATIVE FIMBRIAL
SUBUNIT TYPE 1

(Burkholderia
pseudomallei)
4 / 5 THR A 125
THR A 127
ASP A 123
TYR A 138
None
None
EDO  A 202 (-4.2A)
EDO  A 202 (-3.3A)
1.20A 4oltA-5n2bA:
undetectable
4oltA-5n2bA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB302_1
(CHITOSANASE)
5n2b PUTATIVE FIMBRIAL
SUBUNIT TYPE 1

(Burkholderia
pseudomallei)
4 / 5 THR A 125
THR A 127
ASP A 123
TYR A 138
None
None
EDO  A 202 (-4.2A)
EDO  A 202 (-3.3A)
1.24A 4oltB-5n2bA:
undetectable
4oltB-5n2bA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA302_1
(CHITOSANASE)
5n2b PUTATIVE FIMBRIAL
SUBUNIT TYPE 1

(Burkholderia
pseudomallei)
4 / 5 THR A 125
THR A 127
ASP A 123
TYR A 138
None
None
EDO  A 202 (-4.2A)
EDO  A 202 (-3.3A)
1.21A 4qwpA-5n2bA:
undetectable
4qwpA-5n2bA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB306_1
(CHITOSANASE)
5n2b PUTATIVE FIMBRIAL
SUBUNIT TYPE 1

(Burkholderia
pseudomallei)
4 / 5 THR A 125
THR A 127
ASP A 123
TYR A 138
None
None
EDO  A 202 (-4.2A)
EDO  A 202 (-3.3A)
1.18A 4qwpB-5n2bA:
undetectable
4qwpB-5n2bA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUI_B_CTCB405_0
(TETRACYCLINE
DESTRUCTASE TET(50))
5n2b PUTATIVE FIMBRIAL
SUBUNIT TYPE 1

(Burkholderia
pseudomallei)
5 / 12 GLY A  37
THR A  56
GLY A  73
PHE A  65
ILE A  39
EDO  A 208 (-3.4A)
None
None
None
None
1.03A 5tuiB-5n2bA:
undetectable
5tuiB-5n2bA:
undetectable