SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5n2d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X45_B_HSMB1160_1 (ALLERGEN ARG R 1)	5n2d	PROGRAMMED CELL DEATH 1 LIGAND 1 (Homo sapiens)	4 / 7	TYR A 28 VAL A 128 TYR A 112 ILE A 101	None	1.22A	2x45B-5n2dA: undetectable	2x45B-5n2dA: 15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X45_C_HSMC1160_1 (ALLERGEN ARG R 1)	5n2d	PROGRAMMED CELL DEATH 1 LIGAND 1 (Homo sapiens)	4 / 7	TYR A 28 VAL A 128 TYR A 112 ILE A 101	None	1.21A	2x45C-5n2dA: undetectable	2x45C-5n2dA: 15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WIP_B_ACHB301_0 (ACETYLCHOLINE-BINDIN G PROTEIN)	5n2d	PROGRAMMED CELL DEATH 1 LIGAND 1 (Homo sapiens)	4 / 8	TYR A 112 THR A 37 TYR A 28 TRP A 57	None	1.28A	3wipB-5n2dA: undetectable 3wipC-5n2dA: undetectable	3wipB-5n2dA: 18.70 3wipC-5n2dA: 18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WIP_C_ACHC301_0 (ACETYLCHOLINE-BINDIN G PROTEIN)	5n2d	PROGRAMMED CELL DEATH 1 LIGAND 1 (Homo sapiens)	4 / 8	TYR A 112 THR A 37 TYR A 28 TRP A 57	None	1.33A	3wipC-5n2dA: undetectable 3wipD-5n2dA: undetectable	3wipC-5n2dA: 18.70 3wipD-5n2dA: 18.70

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2X45_B_HSMB1160_1","ALLERGEN ARG R 1","5n2d","PROGRAMMED CELL DEATH 1 LIGAND 1","Homo sapiens",4,"TYR A  28;VAL A 128;TYR A 112;ILE A 101","None","1.22A","2x45B-5n2dA:undetectable","2x45B-5n2dA:15.82"],["2X45_C_HSMC1160_1","ALLERGEN ARG R 1","5n2d","PROGRAMMED CELL DEATH 1 LIGAND 1","Homo sapiens",4,"TYR A  28;VAL A 128;TYR A 112;ILE A 101","None","1.21A","2x45C-5n2dA:undetectable","2x45C-5n2dA:15.82"],["3WIP_B_ACHB301_0","ACETYLCHOLINE-BINDING PROTEIN","5n2d","PROGRAMMED CELL DEATH 1 LIGAND 1","Homo sapiens",4,"TYR A 112;THR A  37;TYR A  28;TRP A  57","None","1.28A","3wipB-5n2dA:undetectable;3wipC-5n2dA:undetectable","3wipB-5n2dA:18.70;3wipC-5n2dA:18.70"],["3WIP_C_ACHC301_0","ACETYLCHOLINE-BINDING PROTEIN","5n2d","PROGRAMMED CELL DEATH 1 LIGAND 1","Homo sapiens",4,"TYR A 112;THR A  37;TYR A  28;TRP A  57","None","1.33A","3wipC-5n2dA:undetectable;3wipD-5n2dA:undetectable","3wipC-5n2dA:18.70;3wipD-5n2dA:18.70"]]