SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5n2g'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA501_1
(CYTOCHROME P450 2B4)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		4 / 7 SER A 111
LEU A 488
GLY A 482
THR A 659
 None
 1.01A 2bdmA-5n2gA:
undetectable		 2bdmA-5n2gA:
11.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_F_TACF3888_1
(ELONGATION FACTOR
EF-TU)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		4 / 7 THR A 567
SER A 683
SER A 680
LEU A 510
 None
 1.04A 2hdnE-5n2gA:
undetectable
2hdnF-5n2gA:
5.4
2hdnH-5n2gA:
5.4		 2hdnE-5n2gA:
16.18
2hdnF-5n2gA:
12.13
2hdnH-5n2gA:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_H_TACH4888_1
(ELONGATION FACTOR
EF-TU)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		4 / 7 SER A 680
LEU A 510
THR A 567
SER A 683
 None
 1.04A 2hdnF-5n2gA:
5.4
2hdnG-5n2gA:
undetectable
2hdnH-5n2gA:
5.4		 2hdnF-5n2gA:
12.13
2hdnG-5n2gA:
16.18
2hdnH-5n2gA:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O5Y_H_STRH249_1
(CHIMERIC ANTIBODY
FAB 1E9-DB3)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		4 / 7 ASN A 562
GLY A 621
THR A 622
SER A 683
 None
 1.28A 2o5yH-5n2gA:
undetectable
2o5yL-5n2gA:
undetectable		 2o5yH-5n2gA:
16.34
2o5yL-5n2gA:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_F_CSCF1383_2
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		3 / 3 LEU A 887
MET A 891
MET A 842
 None
 0.99A 2vavF-5n2gA:
undetectable		 2vavF-5n2gA:
11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		4 / 6 ASP A 268
TYR A 271
PHE A 328
LEU A 297
 MN  A1105 (-3.4A)
None
None
None
 1.20A 2w98A-5n2gA:
undetectable
2w98B-5n2gA:
undetectable		 2w98A-5n2gA:
12.90
2w98B-5n2gA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		4 / 6 ASP A 330
TYR A 332
TYR A 473
PHE A 164
 None
None
DTT  A1110 (-4.7A)
None
 1.19A 2w98A-5n2gA:
undetectable
2w98B-5n2gA:
undetectable		 2w98A-5n2gA:
12.90
2w98B-5n2gA:
12.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_A_9PLA501_1
(CYTOCHROME P450 2A6)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		5 / 11 PHE A 560
PHE A 722
ILE A 690
GLY A 691
PHE A 784
 None
 0.91A 3t3rA-5n2gA:
undetectable		 3t3rA-5n2gA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		5 / 9 PHE A 560
PHE A 722
ILE A 690
GLY A 691
PHE A 784
 None
 0.93A 3t3rB-5n2gA:
undetectable		 3t3rB-5n2gA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_C_9PLC501_1
(CYTOCHROME P450 2A6)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		5 / 9 PHE A 560
PHE A 722
ILE A 690
GLY A 691
PHE A 784
 None
 0.94A 3t3rC-5n2gA:
undetectable		 3t3rC-5n2gA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		5 / 10 PHE A 560
PHE A 722
ILE A 690
GLY A 691
PHE A 784
 None
 0.93A 3t3rD-5n2gA:
0.5		 3t3rD-5n2gA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5V_A_ACTA511_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		4 / 4 ASN A 543
PHE A 541
SER A 542
GLN A 538
 None
 1.14A 3v5vA-5n2gA:
1.5		 3v5vA-5n2gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VNS_A_DVAA602_0
(NRPS ADENYLATION
PROTEIN CYTC1)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		4 / 7 ASP A 373
PHE A 415
GLY A 358
THR A 375
 None
 1.06A 3vnsA-5n2gA:
undetectable		 3vnsA-5n2gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		5 / 12 ILE A 695
GLY A 750
ILE A 547
ASP A 549
ASN A 779
 None
None
None
MN  A1106 ( 4.6A)
None
 1.22A 4a81A-5n2gA:
2.1		 4a81A-5n2gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJJ_C_NCTC501_1
(CYTOCHROME P450 2A6)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		4 / 5 PHE A 560
PHE A 722
ILE A 690
GLY A 691
 None
 0.86A 4ejjC-5n2gA:
undetectable		 4ejjC-5n2gA:
8.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		5 / 12 ASP A 881
TRP A 940
MET A 842
LEU A 889
PHE A 838
 None
 1.36A 4iaqA-5n2gA:
2.0		 4iaqA-5n2gA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAQ_A_2GMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		5 / 12 TRP A 940
PHE A 972
MET A 842
LEU A 889
PHE A 838
 None
 1.17A 4iaqA-5n2gA:
2.0		 4iaqA-5n2gA:
10.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		5 / 12 TRP A 940
PHE A 972
MET A 842
LEU A 889
PHE A 838
 None
 1.13A 4iarA-5n2gA:
undetectable		 4iarA-5n2gA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		5 / 12 ASN A 720
ARG A 727
LEU A 783
ILE A 778
LEU A 712
 None
 1.36A 4k36A-5n2gA:
undetectable		 4k36A-5n2gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		5 / 12 TYR A 697
TYR A 550
ASN A 785
VAL A 782
ILE A 778
 None
 1.47A 4k36A-5n2gA:
undetectable		 4k36A-5n2gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		5 / 12 ASN A 720
ARG A 727
LEU A 783
ILE A 778
LEU A 712
 None
 1.33A 4k36B-5n2gA:
undetectable		 4k36B-5n2gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K36_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		5 / 12 TYR A 697
TYR A 550
ASN A 785
VAL A 782
ILE A 778
 None
 1.45A 4k36B-5n2gA:
undetectable		 4k36B-5n2gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K37_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		5 / 11 ASN A 720
ARG A 727
LEU A 783
ILE A 778
LEU A 712
 None
 1.27A 4k37B-5n2gA:
undetectable		 4k37B-5n2gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K37_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		5 / 11 TYR A 697
TYR A 550
ASN A 785
VAL A 782
ILE A 778
 None
 1.45A 4k37B-5n2gA:
undetectable		 4k37B-5n2gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K39_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		5 / 12 TYR A 697
TYR A 550
ASN A 785
VAL A 782
ILE A 778
 None
 1.43A 4k39A-5n2gA:
undetectable		 4k39A-5n2gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOV_A_KOVA204_1
(UNCHARACTERIZED
PROTEIN)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		5 / 12 TYR A 458
GLY A 392
ASN A 393
TYR A 468
LEU A 346
 None
 1.44A 4kovA-5n2gA:
undetectable		 4kovA-5n2gA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA302_0
(THAUMATIN-1)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		3 / 3 ARG A 223
GLN A 214
GLU A 210
 None
 0.93A 4tvtA-5n2gA:
undetectable		 4tvtA-5n2gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1F_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		5 / 12 ASP A 867
LEU A 983
PHE A 997
LEU A 872
ILE A 868
 None
 1.08A 4x1fA-5n2gA:
undetectable		 4x1fA-5n2gA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1G_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		5 / 12 ASP A 867
LEU A 983
PHE A 997
LEU A 872
ILE A 868
 None
 1.09A 4x1gA-5n2gA:
undetectable		 4x1gA-5n2gA:
12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_2
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		4 / 6 PHE A 992
LEU A 983
ASN A 981
ARG A 995
 None
 1.08A 4yv5B-5n2gA:
undetectable		 4yv5B-5n2gA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z7F_A_FOLA201_0
(FOLATE ECF
TRANSPORTER)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		5 / 12 LEU A 341
SER A 338
ASP A 330
PHE A 262
THR A 261
 None
 1.01A 4z7fA-5n2gA:
undetectable		 4z7fA-5n2gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_E_ACTE406_0
(PROTON-GATED ION
CHANNEL)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		4 / 5 ILE A 327
ILE A   6
TYR A 258
GLU A 476
 MES  A1103 ( 4.9A)
None
None
None
 1.26A 4zzcE-5n2gA:
2.5		 4zzcE-5n2gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_N_EVPN2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		4 / 6 GLU A 822
GLY A 372
ASP A 373
GLY A 358
 None
 0.92A 5cdnR-5n2gA:
2.5
5cdnS-5n2gA:
undetectable		 5cdnR-5n2gA:
10.17
5cdnS-5n2gA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_P_EVPP2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		4 / 6 GLU A 822
GLY A 372
ASP A 373
GLY A 358
 None
 0.93A 5cdnT-5n2gA:
undetectable
5cdnU-5n2gA:
undetectable		 5cdnT-5n2gA:
10.17
5cdnU-5n2gA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_D_READ602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		5 / 12 ILE A 619
GLU A 620
GLY A 621
ARG A 625
CYH A  83
 None
 1.28A 5fhzD-5n2gA:
undetectable		 5fhzD-5n2gA:
11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L1F_A_6ZPA902_1
(GLUTAMATE RECEPTOR 2)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		4 / 8 ASP A 290
PRO A 289
PHE A  17
SER A  11
 None
 1.13A 5l1fA-5n2gA:
undetectable
5l1fB-5n2gA:
undetectable		 5l1fA-5n2gA:
6.63
5l1fB-5n2gA:
6.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_B_NIZB808_1
(CATALASE-PEROXIDASE)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		4 / 8 GLU A 471
VAL A 260
GLY A 474
THR A 477
 None
 0.96A 5sxqB-5n2gA:
1.7		 5sxqB-5n2gA:
7.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA809_1
(CATALASE-PEROXIDASE)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		4 / 8 GLU A 471
VAL A 260
GLY A 474
THR A 477
 None
 0.93A 5syjA-5n2gA:
undetectable		 5syjA-5n2gA:
8.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_0
(REGULATORY PROTEIN
TETR)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		5 / 12 ILE A 597
ARG A 617
VAL A 557
CYH A 558
PHE A 787
 None
 1.18A 5vlmE-5n2gA:
undetectable		 5vlmE-5n2gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA503_1
(CYTOCHROME P450 2C9)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		5 / 12 ILE A 502
PHE A 630
LEU A 631
LEU A 563
LEU A 678
 None
 1.12A 5xxiA-5n2gA:
undetectable		 5xxiA-5n2gA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YW0_A_ACTA409_0
(UNCHARACTERIZED
PROTEIN KDOO)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		3 / 3 ASP A 984
PHE A 541
ARG A 746
 None
 1.12A 5yw0A-5n2gA:
undetectable		 5yw0A-5n2gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_B_SAMB505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		5 / 12 ILE A 695
TYR A 550
TYR A 554
ARG A 692
GLY A 691
 None
 1.43A 6bp4B-5n2gA:
undetectable		 6bp4B-5n2gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EP4_A_DMEA601_1
(CHOLINESTERASE)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		4 / 5 TYR A1004
GLU A 978
TYR A 932
HIS A 839
 None
 1.27A 6ep4A-5n2gA:
undetectable		 6ep4A-5n2gA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA825_0
(GEPHYRIN)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		3 / 3 LYS A  62
VAL A  85
ASP A  87
 None
 0.65A 6fgdA-5n2gA:
undetectable		 6fgdA-5n2gA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_1
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 5n2g DNA POLYMERASE
(Vaccinia
virus) 		3 / 3 ASP A 875
SER A 884
SER A 882
 None
 0.75A 6mxtA-5n2gA:
undetectable		 6mxtA-5n2gA:
undetectable