SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5n2u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ICV_D_NIOD706_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5n2u NUCLEOPROTEIN
(Influenza
D
virus) 		4 / 5 GLU A 333
GLY A 335
THR A 320
PHE A 319
 None
 1.14A 1icvC-5n2uA:
undetectable
1icvD-5n2uA:
undetectable		 1icvC-5n2uA:
17.41
1icvD-5n2uA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_B_FOLB401_1
(DIHYDROFOLATE
REDUCTASE)		 5n2u NUCLEOPROTEIN
(Influenza
D
virus) 		3 / 3 GLU A 287
GLN A  25
ARG A  29
 None
 0.88A 2w3bB-5n2uA:
undetectable		 2w3bB-5n2uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDR_A_GJZA506_1
(CHOLESTEROL
24-HYDROXYLASE)		 5n2u NUCLEOPROTEIN
(Influenza
D
virus) 		4 / 6 LEU A 264
PHE A 231
ALA A 439
THR A 462
 None
 0.76A 3mdrA-5n2uA:
undetectable		 3mdrA-5n2uA:
11.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MEG_A_T27A561_1
(P66 REVERSE
TRANSCRIPTASE)		 5n2u NUCLEOPROTEIN
(Influenza
D
virus) 		5 / 12 PRO A 266
LEU A 162
ASN A 155
VAL A 186
LEU A 262
 None
 1.49A 3megA-5n2uA:
undetectable		 3megA-5n2uA:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)		 5n2u NUCLEOPROTEIN
(Influenza
D
virus) 		4 / 7 GLN A 432
ARG A 433
PHE A 231
PRO A 232
 None
 1.32A 3ql6A-5n2uA:
undetectable		 3ql6A-5n2uA:
10.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J24_D_ESTD600_1
(ESTROGEN RECEPTOR
BETA)		 5n2u NUCLEOPROTEIN
(Influenza
D
virus) 		5 / 12 MET A 257
LEU A 193
ILE A 223
LEU A 219
LEU A 238
 None
 1.24A 4j24D-5n2uA:
undetectable		 4j24D-5n2uA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5n2u NUCLEOPROTEIN
(Influenza
D
virus) 		4 / 6 PHE A 500
MET A 365
ARG A 368
VAL A 373
 None
 1.27A 4mk4B-5n2uA:
undetectable		 4mk4B-5n2uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_B_ESTB601_1
(ESTROGEN RECEPTOR
BETA)		 5n2u NUCLEOPROTEIN
(Influenza
D
virus) 		5 / 12 MET A 257
LEU A 193
ILE A 223
LEU A 219
LEU A 238
 None
 1.22A 5toaB-5n2uA:
undetectable		 5toaB-5n2uA:
15.61