SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5n38'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FE2_A_LAXA700_1 (PROSTAGLANDIN ENDOPEROXIDE H SYNTHASE-1)	5n38	E3 UBIQUITIN-PROTEIN LIGASE PARKIN,E3 UBIQUITIN-PROTEIN LIGASE PARKIN (Homo sapiens)	5 / 10	VAL A 56 VAL A 36 VAL A 5 ILE A 2 LEU A 26	None	1.14A	1fe2A-5n38A: undetectable	1fe2A-5n38A: 18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Z97_A_CAMA422_0 (CYTOCHROME P450-CAM)	5n38	E3 UBIQUITIN-PROTEIN LIGASE PARKIN,E3 UBIQUITIN-PROTEIN LIGASE PARKIN (Homo sapiens)	4 / 6	THR A 21 VAL A 29 VAL A 67 VAL A 5	None	0.95A	2z97A-5n38A: undetectable	2z97A-5n38A: 18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4PM5_A_CE3A301_2 (BETA-LACTAMASE CTX-M-14)	5n38	E3 UBIQUITIN-PROTEIN LIGASE PARKIN,E3 UBIQUITIN-PROTEIN LIGASE PARKIN (Homo sapiens)	3 / 3	CYH A 238 PRO A 247 ASP A 262	ZN A2503 ( 2.3A) None None	0.99A	4pm5A-5n38A: undetectable	4pm5A-5n38A: 18.87