SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5n3u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3003_1
(SERUM ALBUMIN)		 5n3u PHYCOCYANOBILIN
LYASE SUBUNIT ALPHA
(Nostoc
sp.
PCC
7120) 		3 / 4 LYS A 260
ALA A 265
MET A 252
 None
 0.97A 1hk3A-5n3uA:
undetectable		 1hk3A-5n3uA:
9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_2
(HIV-II PROTEASE)		 5n3u PHYCOCYANOBILIN
LYASE SUBUNIT ALPHA
(Nostoc
sp.
PCC
7120) 		5 / 9 ALA A 185
ILE A 164
GLY A 159
ILE A 158
ILE A 167
 None
 0.77A 1hshB-5n3uA:
undetectable		 1hshB-5n3uA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_2
(HIV-1 PROTEASE)		 5n3u PHYCOCYANOBILIN
LYASE SUBUNIT ALPHA
(Nostoc
sp.
PCC
7120) 		6 / 11 ARG A  34
LEU A  73
ALA A  78
VAL A 104
GLY A  92
ILE A  56
 None
 1.43A 1hxwB-5n3uA:
undetectable		 1hxwB-5n3uA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B60_B_RITB100_1
(GAG-POL POLYPROTEIN)		 5n3u PHYCOCYANOBILIN
LYASE SUBUNIT ALPHA
(Nostoc
sp.
PCC
7120) 		5 / 12 ALA A 185
ILE A 164
GLY A 159
ILE A 158
ILE A 167
 None
 0.83A 2b60A-5n3uA:
undetectable		 2b60A-5n3uA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2002_1
(SERUM ALBUMIN)		 5n3u PHYCOCYANOBILIN
LYASE SUBUNIT ALPHA
(Nostoc
sp.
PCC
7120) 		5 / 10 ALA A  38
LEU A  26
LEU A  55
ALA A  58
SER A 111
 None
 1.09A 2bxeA-5n3uA:
undetectable		 2bxeA-5n3uA:
9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YJA_B_ESTB1550_1
(ESTROGEN RECEPTOR)		 5n3u PHYCOCYANOBILIN
LYASE SUBUNIT ALPHA
(Nostoc
sp.
PCC
7120) 		5 / 12 ALA A 229
GLU A 228
ARG A 267
ILE A 221
GLY A 196
 None
 1.18A 2yjaB-5n3uA:
undetectable		 2yjaB-5n3uA:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5n3u PHYCOCYANOBILIN
LYASE SUBUNIT BETA
(Nostoc
sp.
PCC
7120) 		5 / 10 ILE B  71
ILE B  83
LYS B 116
GLY B 117
VAL B  64
 None
 1.22A 3em0A-5n3uB:
undetectable		 3em0A-5n3uB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ITA_D_AICD501_1
(D-ALANYL-D-ALANINE
CARBOXYPEPTIDASE
DACC)		 5n3u PHYCOCYANOBILIN
LYASE SUBUNIT ALPHA
(Nostoc
sp.
PCC
7120) 		3 / 3 PRO A 174
PHE A 170
ALA A 135
 None
 0.56A 3itaD-5n3uA:
undetectable		 3itaD-5n3uA:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		 5n3u PHYCOCYANOBILIN
LYASE SUBUNIT BETA
(Nostoc
sp.
PCC
7120) 		5 / 12 GLY B 117
ARG B  79
ALA B 101
ALA B 102
ASP B 105
 None
 1.12A 3keeA-5n3uB:
undetectable		 3keeA-5n3uB:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_A_SAMA220_0
(16S RRNA METHYLASE)		 5n3u PHYCOCYANOBILIN
LYASE SUBUNIT BETA
(Nostoc
sp.
PCC
7120) 		5 / 12 GLY B 119
ALA B 114
ALA B 115
THR B 141
LEU B 142
 None
 0.91A 3mteA-5n3uB:
undetectable		 3mteA-5n3uB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU4_B_478B401_2
(PROTEASE)		 5n3u PHYCOCYANOBILIN
LYASE SUBUNIT ALPHA
(Nostoc
sp.
PCC
7120) 		5 / 9 ALA A 185
ILE A 164
GLY A 159
ILE A 158
ILE A 167
 None
 0.84A 3nu4B-5n3uA:
undetectable		 3nu4B-5n3uA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_0
(16S RRNA METHYLASE)		 5n3u PHYCOCYANOBILIN
LYASE SUBUNIT BETA
(Nostoc
sp.
PCC
7120) 		5 / 12 GLY B 119
ALA B 114
ALA B 115
THR B 141
LEU B 142
 None
 0.94A 3p2kA-5n3uB:
undetectable		 3p2kA-5n3uB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_0
(16S RRNA METHYLASE)		 5n3u PHYCOCYANOBILIN
LYASE SUBUNIT ALPHA
(Nostoc
sp.
PCC
7120) 		5 / 12 GLY A  82
GLY A  85
VAL A  52
ALA A  77
ALA A  78
 None
 1.09A 3p2kC-5n3uA:
undetectable		 3p2kC-5n3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_A_BEZA264_0
(ECHA1_1)		 5n3u PHYCOCYANOBILIN
LYASE SUBUNIT ALPHA
(Nostoc
sp.
PCC
7120) 		5 / 8 ILE A 167
LEU A 189
GLU A 153
ALA A 154
ALA A 157
 None
 1.32A 3r9tA-5n3uA:
undetectable		 3r9tA-5n3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_B_BEZB264_0
(ECHA1_1)		 5n3u PHYCOCYANOBILIN
LYASE SUBUNIT ALPHA
(Nostoc
sp.
PCC
7120) 		5 / 7 ILE A 167
LEU A 189
GLU A 153
ALA A 154
ALA A 157
 None
 1.35A 3r9tB-5n3uA:
undetectable		 3r9tB-5n3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9T_C_BEZC264_0
(ECHA1_1)		 5n3u PHYCOCYANOBILIN
LYASE SUBUNIT ALPHA
(Nostoc
sp.
PCC
7120) 		4 / 5 ALA A 220
GLU A 113
GLU A 153
ALA A 157
 None
 1.39A 3r9tC-5n3uA:
undetectable		 3r9tC-5n3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_D_LOCD502_1
(TUBULIN BETA CHAIN)		 5n3u PHYCOCYANOBILIN
LYASE SUBUNIT ALPHA
(Nostoc
sp.
PCC
7120) 		5 / 12 LEU A  84
ALA A  80
LEU A  41
ALA A  58
ILE A  23
 None
 0.99A 3ut5D-5n3uA:
undetectable		 3ut5D-5n3uA:
10.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_A_TPVA500_2
(PROTEASE)		 5n3u PHYCOCYANOBILIN
LYASE SUBUNIT ALPHA
(Nostoc
sp.
PCC
7120) 		5 / 10 LEU A 203
ALA A 243
GLY A 222
ILE A 221
ILE A 230
 None
 1.02A 4njuB-5n3uA:
undetectable		 4njuB-5n3uA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_2
(PROTEASE)		 5n3u PHYCOCYANOBILIN
LYASE SUBUNIT ALPHA
(Nostoc
sp.
PCC
7120) 		5 / 10 LEU A 203
ALA A 243
GLY A 222
ILE A 221
ILE A 230
 None
 1.03A 4njuD-5n3uA:
undetectable		 4njuD-5n3uA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PXM_B_ESTB2000_1
(ESTROGEN RECEPTOR)		 5n3u PHYCOCYANOBILIN
LYASE SUBUNIT ALPHA
(Nostoc
sp.
PCC
7120) 		5 / 11 ALA A 229
GLU A 228
ARG A 267
ILE A 221
GLY A 196
 None
 1.19A 4pxmB-5n3uA:
undetectable		 4pxmB-5n3uA:
13.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_B_LOCB502_1
(TUBULIN BETA CHAIN)		 5n3u PHYCOCYANOBILIN
LYASE SUBUNIT ALPHA
(Nostoc
sp.
PCC
7120) 		5 / 12 LEU A  84
ALA A  80
LEU A  41
ALA A  58
ILE A  23
 None
 0.99A 4x20B-5n3uA:
undetectable		 4x20B-5n3uA:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA603_1
(SERUM ALBUMIN)		 5n3u PHYCOCYANOBILIN
LYASE SUBUNIT ALPHA
(Nostoc
sp.
PCC
7120) 		5 / 10 ALA A 120
LEU A 155
LEU A 112
ALA A 154
ALA A 108
 None
 1.17A 4zbrA-5n3uA:
undetectable		 4zbrA-5n3uA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA603_1
(SERUM ALBUMIN)		 5n3u PHYCOCYANOBILIN
LYASE SUBUNIT ALPHA
(Nostoc
sp.
PCC
7120) 		5 / 10 ALA A 233
LEU A 215
ALA A 214
LEU A 244
ALA A 243
 None
 1.11A 4zbrA-5n3uA:
undetectable		 4zbrA-5n3uA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZF8_A_MYTA502_1
(BIFUNCTIONAL
P-450/NADPH-P450
REDUCTASE)		 5n3u PHYCOCYANOBILIN
LYASE SUBUNIT ALPHA
(Nostoc
sp.
PCC
7120) 		4 / 6 VAL A 200
LEU A 247
ILE A 230
ALA A 229
 None
 0.66A 4zf8A-5n3uA:
undetectable		 4zf8A-5n3uA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5n3u PHYCOCYANOBILIN
LYASE SUBUNIT ALPHA
(Nostoc
sp.
PCC
7120) 		3 / 3 THR A 190
HIS A 173
LEU A 152
 None
 0.71A 5axdA-5n3uA:
undetectable		 5axdA-5n3uA:
10.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DQF_A_LCRA612_1
(SERUM ALBUMIN)		 5n3u PHYCOCYANOBILIN
LYASE SUBUNIT ALPHA
(Nostoc
sp.
PCC
7120) 		5 / 9 LYS A 126
LEU A 127
LEU A 112
LEU A 155
ALA A 154
 None
 1.09A 5dqfA-5n3uA:
undetectable		 5dqfA-5n3uA:
10.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_B_ESTB601_1
(ESTROGEN RECEPTOR)		 5n3u PHYCOCYANOBILIN
LYASE SUBUNIT ALPHA
(Nostoc
sp.
PCC
7120) 		5 / 11 ALA A 229
GLU A 228
ARG A 267
ILE A 221
GLY A 196
 None
 1.17A 5dxbB-5n3uA:
undetectable		 5dxbB-5n3uA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 5n3u PHYCOCYANOBILIN
LYASE SUBUNIT ALPHA
(Nostoc
sp.
PCC
7120) 		3 / 3 ALA A  22
ASN A  25
LEU A  26
 None
 0.28A 5i1nB-5n3uA:
undetectable		 5i1nB-5n3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 5n3u PHYCOCYANOBILIN
LYASE SUBUNIT ALPHA
(Nostoc
sp.
PCC
7120) 		3 / 3 ALA A  22
ASN A  25
LEU A  26
 None
 0.20A 5i1oC-5n3uA:
undetectable		 5i1oC-5n3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 5n3u PHYCOCYANOBILIN
LYASE SUBUNIT ALPHA
(Nostoc
sp.
PCC
7120) 		3 / 3 ALA A  22
ASN A  25
LEU A  26
 None
 0.27A 5i1pA-5n3uA:
undetectable		 5i1pA-5n3uA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ITZ_B_LOCB502_1
(TUBULIN BETA-2B
CHAIN)		 5n3u PHYCOCYANOBILIN
LYASE SUBUNIT ALPHA
(Nostoc
sp.
PCC
7120) 		5 / 12 LEU A  81
ALA A  80
LEU A  41
ALA A  54
ILE A  23
 None
 1.08A 5itzB-5n3uA:
undetectable		 5itzB-5n3uA:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JVZ_A_FLPA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5n3u PHYCOCYANOBILIN
LYASE SUBUNIT ALPHA
(Nostoc
sp.
PCC
7120) 		5 / 12 LEU A  59
VAL A 104
ALA A 108
SER A 111
LEU A 112
 None
 0.87A 5jvzA-5n3uA:
undetectable		 5jvzA-5n3uA:
9.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WGQ_A_ESTA601_1
(ESTROGEN RECEPTOR)		 5n3u PHYCOCYANOBILIN
LYASE SUBUNIT ALPHA
(Nostoc
sp.
PCC
7120) 		5 / 9 ALA A 235
GLU A 236
LEU A 208
GLY A 205
LEU A 203
 None
 1.47A 5wgqA-5n3uA:
undetectable		 5wgqA-5n3uA:
22.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_B_LOCB504_2
(TUBULIN BETA CHAIN)		 5n3u PHYCOCYANOBILIN
LYASE SUBUNIT ALPHA
(Nostoc
sp.
PCC
7120) 		5 / 12 LEU A  84
ALA A  80
LEU A  41
ALA A  58
ILE A  23
 None
 1.01A 5xiwB-5n3uA:
undetectable		 5xiwB-5n3uA:
25.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIW_D_LOCD503_2
(TUBULIN BETA CHAIN)		 5n3u PHYCOCYANOBILIN
LYASE SUBUNIT ALPHA
(Nostoc
sp.
PCC
7120) 		5 / 12 LEU A  84
ALA A  80
LEU A  41
ALA A  58
ILE A  23
 None
 0.87A 5xiwD-5n3uA:
undetectable		 5xiwD-5n3uA:
25.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA824_0
(GEPHYRIN)		 5n3u PHYCOCYANOBILIN
LYASE SUBUNIT BETA
(Nostoc
sp.
PCC
7120) 		4 / 4 LEU B 126
ASP B  91
PRO B  92
ARG B  93
 None
 0.64A 6fgdA-5n3uB:
undetectable		 6fgdA-5n3uB:
undetectable