SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5n47'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		 5n47 FIBRONECTIN
(Homo
sapiens) 		4 / 6 THR B1423
GLU B1424
MET B1374
PHE B1366
 None
 1.42A 2w98B-5n47B:
undetectable		 2w98B-5n47B:
13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_D_CGED501_1
(CYTOCHROME P450 2B4)		 5n47 FIBRONECTIN
(Homo
sapiens) 		5 / 9 VAL B1414
ILE B1407
ALA B1403
VAL B1427
VAL B1429
 None
 1.21A 3me6D-5n47B:
undetectable		 3me6D-5n47B:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_B_OAQB302_0
(SULFOTRANSFERASE)		 5n47 FIBRONECTIN
(Homo
sapiens) 		5 / 12 ILE B1336
VAL B1276
ILE B1278
SER B1274
LEU B1328
 None
 1.32A 5tiwB-5n47B:
undetectable		 5tiwB-5n47B:
undetectable