SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5n48'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_2
(TRANSTHYRETIN)		 5n48 NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN
(Homo
sapiens) 		4 / 8 LEU A 144
THR A 136
LEU A 148
VAL A 121
 None
 0.90A 1sn5C-5n48A:
undetectable		 1sn5C-5n48A:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 5n48 NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN
(Homo
sapiens) 		4 / 7 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
 0.99A 1t87A-5n48A:
undetectable		 1t87A-5n48A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_B_9CRB130_1
(TRANSTHYRETIN)		 5n48 NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN
(Homo
sapiens) 		4 / 7 LEU A 144
THR A 136
LEU A 148
VAL A 121
 None
 0.90A 1tyrB-5n48A:
undetectable		 1tyrB-5n48A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 5n48 NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN
(Homo
sapiens) 		4 / 7 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
 0.97A 2a1mA-5n48A:
undetectable		 2a1mA-5n48A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD5_A_CHDA702_0
(FERROCHELATASE)		 5n48 NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN
(Homo
sapiens) 		3 / 3 LEU A 161
PRO A 162
ARG A  36
 None
 0.48A 2qd5A-5n48A:
undetectable		 2qd5A-5n48A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_1
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 5n48 FIBRONECTIN
(Homo
sapiens) 		3 / 3 SER B1282
ASP B1280
ASP B1277
 None
 0.92A 3iv6C-5n48B:
undetectable		 3iv6C-5n48B:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7T_A_5FWA1001_1
(SUPEROXIDE DISMUTASE
[CU-ZN])		 5n48 NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN
(Homo
sapiens) 		3 / 3 ASP A  47
LYS A  46
ASP A  45
 None
 0.79A 4a7tA-5n48A:
undetectable		 4a7tA-5n48A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK6_B_LURB201_1
(TRANSTHYRETIN)		 5n48 NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN
(Homo
sapiens) 		4 / 8 LEU A 144
THR A 136
LEU A 148
VAL A 121
 None
 0.89A 4ik6B-5n48A:
undetectable		 4ik6B-5n48A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IK7_B_IMNB201_1
(TRANSTHYRETIN)		 5n48 NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN
(Homo
sapiens) 		4 / 8 LEU A 144
THR A 136
LEU A 148
VAL A 121
 None
 0.86A 4ik7B-5n48A:
undetectable		 4ik7B-5n48A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5n48 NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN
(Homo
sapiens) 		4 / 7 PHE A  83
TYR A  56
THR A  54
VAL A 121
 None
 0.97A 4l4gA-5n48A:
undetectable		 4l4gA-5n48A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4S0V_A_SUVA2001_2
(HUMAN OREXIN
RECEPTOR TYPE 2
FUSION PROTEIN TO P.
ABYSII GLYCOGEN
SYNTHASE)		 5n48 FIBRONECTIN
NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN
(Homo
sapiens) 		4 / 5 ILE A  97
PRO A 103
TYR B1323
VAL B1325
 None
 1.16A 4s0vA-5n48A:
undetectable		 4s0vA-5n48A:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M66_D_ADND502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5n48 FIBRONECTIN
NEUTROPHIL
GELATINASE-ASSOCIATE
D LIPOCALIN
(Homo
sapiens) 		3 / 3 THR A 104
THR B1301
LEU A   7
 None
 0.62A 5m66D-5n48A:
undetectable		 5m66D-5n48A:
9.81