SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5n4l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_A_DCFA353_1
(ADENOSINE DEAMINASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 12 HIS A 974
HIS A1014
ALA A 165
HIS A 162
HIS A 101
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
None
CU  A1101 (-3.3A)
CU  A1105 (-3.1A)
1.24A 1a4lA-5n4lA:
undetectable
1a4lA-5n4lA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_1
(ADENOSINE DEAMINASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 12 HIS A 974
HIS A1014
ALA A 165
HIS A 162
HIS A 101
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
None
CU  A1101 (-3.3A)
CU  A1105 (-3.1A)
1.20A 1a4lC-5n4lA:
undetectable
1a4lC-5n4lA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_A_ESTA1_1
(ESTROGEN RECEPTOR)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 10 ALA A 277
LEU A 316
MET A 315
ILE A  26
LEU A 328
None
None
None
None
CU  A1103 (-4.4A)
1.40A 1a52A-5n4lA:
undetectable
1a52A-5n4lA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A52_B_ESTB2_1
(ESTROGEN RECEPTOR)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 10 ALA A 277
LEU A 316
MET A 315
ILE A  26
LEU A 328
None
None
None
None
CU  A1103 (-4.4A)
1.40A 1a52B-5n4lA:
undetectable
1a52B-5n4lA:
14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT6_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 11 LEU A 893
LEU A 993
VAL A 971
LEU A1001
HIS A 812
None
1.21A 1kt6A-5n4lA:
undetectable
1kt6A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT7_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 11 LEU A 893
LEU A 993
VAL A 971
LEU A1001
HIS A 812
None
1.28A 1kt7A-5n4lA:
undetectable
1kt7A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHV_A_NOGA301_1
(SEX HORMONE-BINDING
GLOBULIN)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 8 SER A 516
ASP A 570
ASN A 571
LEU A 453
None
1.06A 1lhvA-5n4lA:
undetectable
1lhvA-5n4lA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_0
(MODIFICATION
METHYLASE RSRI)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 12 ASP A 629
PHE A 525
SER A 516
VAL A 518
ALA A 624
None
1.30A 1nw5A-5n4lA:
undetectable
1nw5A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 631
CYH A 674
HIS A 679
MET A 684
None
0.64A 1oe1A-5n4lA:
9.9
1oe1A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE1_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 969
CYH A1015
HIS A1020
MET A1025
CU  A1102 (-3.0A)
CU  A1102 (-1.9A)
CU  A1102 (-3.2A)
CU  A1102 (-3.2A)
0.46A 1oe1A-5n4lA:
9.9
1oe1A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 631
CYH A 674
HIS A 679
MET A 684
None
0.67A 1oe2A-5n4lA:
18.2
1oe2A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 969
CYH A1015
HIS A1020
MET A1025
CU  A1102 (-3.0A)
CU  A1102 (-1.9A)
CU  A1102 (-3.2A)
CU  A1102 (-3.2A)
0.46A 1oe2A-5n4lA:
18.2
1oe2A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 631
CYH A 674
HIS A 679
MET A 684
None
0.68A 1oe3A-5n4lA:
21.5
1oe3A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE3_A_CUA501_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 969
CYH A1015
HIS A1020
MET A1025
CU  A1102 (-3.0A)
CU  A1102 (-1.9A)
CU  A1102 (-3.2A)
CU  A1102 (-3.2A)
0.49A 1oe3A-5n4lA:
21.5
1oe3A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PCG_A_ESTA1_1
(ESTROGEN RECEPTOR)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 10 ALA A 277
LEU A 316
MET A 315
ILE A  26
LEU A 328
None
None
None
None
CU  A1103 (-4.4A)
1.34A 1pcgA-5n4lA:
undetectable
1pcgA-5n4lA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 11 SER A 866
TYR A 905
SER A 856
PHE A 799
VAL A 858
None
1.43A 1q23J-5n4lA:
undetectable
1q23J-5n4lA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_A_ESTA600_1
(ESTRADIOL RECEPTOR)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 10 ALA A 277
LEU A 316
MET A 315
ILE A  26
LEU A 328
None
None
None
None
CU  A1103 (-4.4A)
1.32A 1qkuA-5n4lA:
undetectable
1qkuA-5n4lA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_B_ESTB600_1
(ESTRADIOL RECEPTOR)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 10 ALA A 277
LEU A 316
MET A 315
ILE A  26
LEU A 328
None
None
None
None
CU  A1103 (-4.4A)
1.32A 1qkuB-5n4lA:
undetectable
1qkuB-5n4lA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKU_C_ESTC600_1
(ESTRADIOL RECEPTOR)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 10 ALA A 277
LEU A 316
MET A 315
ILE A  26
LEU A 328
None
None
None
None
CU  A1103 (-4.4A)
1.31A 1qkuC-5n4lA:
undetectable
1qkuC-5n4lA:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QWC_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 ARG A 839
VAL A 874
TRP A 852
None
1.24A 1qwcA-5n4lA:
undetectable
1qwcA-5n4lA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RKY_A_CUA801_0
(LYSYL OXIDASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 HIS A1014
HIS A1016
HIS A 972
CU  A1101 (-3.2A)
CU  A1104 (-3.1A)
CU  A1105 (-3.3A)
0.67A 1rkyA-5n4lA:
undetectable
1rkyA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_2
(PROTEASE RETROPEPSIN)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 12 ALA A 102
VAL A  88
ILE A  78
GLY A 175
ILE A 174
None
0.83A 1sdtB-5n4lA:
undetectable
1sdtB-5n4lA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDV_B_MK1B902_2
(PROTEASE RETROPEPSIN)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 11 ALA A 102
VAL A  88
ILE A  78
GLY A 175
ILE A 174
None
0.83A 1sdvB-5n4lA:
undetectable
1sdvB-5n4lA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN5_C_T3C601_1
(TRANSTHYRETIN)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 6 LYS A 656
LEU A 658
LEU A 621
VAL A 630
None
1.17A 1sn5A-5n4lA:
undetectable
1sn5A-5n4lA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQ5_D_PAUD6004_0
(PANTOTHENATE KINASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 10 VAL A 690
GLY A 614
LEU A 613
TYR A 688
ILE A 617
None
1.49A 1sq5D-5n4lA:
undetectable
1sq5D-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VAG_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 ARG A 839
VAL A 874
TRP A 852
None
1.27A 1vagA-5n4lA:
undetectable
1vagA-5n4lA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VID_A_SAMA301_0
(CATECHOL
O-METHYLTRANSFERASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 12 ASN A 605
GLU A 424
GLY A 608
MET A 611
HIS A 425
None
1.29A 1vidA-5n4lA:
undetectable
1vidA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_A_CUA701_0
(AMINE OXIDASE,
COPPER CONTAINING)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 HIS A 101
HIS A 160
HIS A 162
CU  A1105 (-3.1A)
CU  A1104 (-3.6A)
CU  A1101 (-3.3A)
0.72A 1w2zA-5n4lA:
undetectable
1w2zA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_B_CUB701_0
(AMINE OXIDASE,
COPPER CONTAINING)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 HIS A 101
HIS A 160
HIS A 162
CU  A1105 (-3.1A)
CU  A1104 (-3.6A)
CU  A1101 (-3.3A)
0.70A 1w2zB-5n4lA:
undetectable
1w2zB-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_C_CUC701_0
(AMINE OXIDASE,
COPPER CONTAINING)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 HIS A 101
HIS A 160
HIS A 162
CU  A1105 (-3.1A)
CU  A1104 (-3.6A)
CU  A1101 (-3.3A)
0.70A 1w2zC-5n4lA:
undetectable
1w2zC-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W2Z_D_CUD701_0
(AMINE OXIDASE,
COPPER CONTAINING)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 HIS A 101
HIS A 160
HIS A 162
CU  A1105 (-3.1A)
CU  A1104 (-3.6A)
CU  A1101 (-3.3A)
0.69A 1w2zD-5n4lA:
undetectable
1w2zD-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_A_ADNA433_2
(ADENOSYLHOMOCYSTEINA
SE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 THR A1028
GLU A 112
HIS A 972
None
CA  A1106 (-4.7A)
CU  A1105 (-3.3A)
0.92A 1xwfA-5n4lA:
undetectable
1xwfA-5n4lA:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_B_ADNB433_2
(ADENOSYLHOMOCYSTEINA
SE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 THR A1028
GLU A 112
HIS A 972
None
CA  A1106 (-4.7A)
CU  A1105 (-3.3A)
0.91A 1xwfB-5n4lA:
undetectable
1xwfB-5n4lA:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_C_ADNC433_2
(ADENOSYLHOMOCYSTEINA
SE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 THR A1028
GLU A 112
HIS A 972
None
CA  A1106 (-4.7A)
CU  A1105 (-3.3A)
0.89A 1xwfC-5n4lA:
undetectable
1xwfC-5n4lA:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_D_ADND433_2
(ADENOSYLHOMOCYSTEINA
SE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 THR A1028
GLU A 112
HIS A 972
None
CA  A1106 (-4.7A)
CU  A1105 (-3.3A)
0.89A 1xwfD-5n4lA:
undetectable
1xwfD-5n4lA:
11.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_1
(CES1 PROTEIN)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 12 GLY A 501
VAL A 460
LEU A 510
SER A 511
LEU A 540
None
1.36A 1ya4B-5n4lA:
undetectable
1ya4B-5n4lA:
10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_A_IMNA379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 12 THR A 666
PRO A 664
PRO A 837
SER A 636
VAL A 690
None
1.44A 1z9hA-5n4lA:
undetectable
1z9hA-5n4lA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_B_IMNB381_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 12 THR A 666
PRO A 664
PRO A 837
SER A 636
VAL A 690
None
1.44A 1z9hB-5n4lA:
undetectable
1z9hB-5n4lA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_C_IMNC379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 12 THR A 666
PRO A 664
PRO A 837
SER A 636
VAL A 690
None
1.43A 1z9hC-5n4lA:
undetectable
1z9hC-5n4lA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVI_A_H4BA901_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 ARG A 839
VAL A 874
TRP A 852
None
1.27A 1zviA-5n4lA:
undetectable
1zviA-5n4lA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BTE_D_LEUD1893_0
(AMINOACYL-TRNA
SYNTHETASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 8 ASP A 671
SER A 636
TYR A 634
TYR A 855
None
1.38A 2bteD-5n4lA:
undetectable
2bteD-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CL5_B_SAMB1217_0
(CATECHOL
O-METHYLTRANSFERASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 12 ASN A 605
GLU A 424
GLY A 608
MET A 611
HIS A 425
None
1.32A 2cl5B-5n4lA:
undetectable
2cl5B-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQD_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 631
CYH A 674
HIS A 679
MET A 684
None
0.69A 2fqdA-5n4lA:
25.5
2fqdA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQD_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 969
CYH A1015
HIS A1020
MET A1025
CU  A1102 (-3.0A)
CU  A1102 (-1.9A)
CU  A1102 (-3.2A)
CU  A1102 (-3.2A)
0.39A 2fqdA-5n4lA:
25.5
2fqdA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 631
CYH A 674
HIS A 679
MET A 684
None
0.60A 2fqeA-5n4lA:
25.5
2fqeA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 969
CYH A1015
HIS A1020
MET A1025
CU  A1102 (-3.0A)
CU  A1102 (-1.9A)
CU  A1102 (-3.2A)
CU  A1102 (-3.2A)
0.33A 2fqeA-5n4lA:
25.5
2fqeA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 101
HIS A 103
HIS A 972
HIS A 974
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
0.61A 2fqeA-5n4lA:
25.5
2fqeA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 972
HIS A 974
HIS A 101
HIS A 103
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
0.76A 2fqeA-5n4lA:
25.5
2fqeA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 631
CYH A 674
HIS A 679
MET A 684
None
0.60A 2fqfA-5n4lA:
5.3
2fqfA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 969
CYH A1015
HIS A1020
MET A1025
CU  A1102 (-3.0A)
CU  A1102 (-1.9A)
CU  A1102 (-3.2A)
CU  A1102 (-3.2A)
0.31A 2fqfA-5n4lA:
5.3
2fqfA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 101
HIS A 103
HIS A 972
HIS A 974
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
0.60A 2fqfA-5n4lA:
25.4
2fqfA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 972
HIS A 974
HIS A 101
HIS A 103
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
0.73A 2fqfA-5n4lA:
25.4
2fqfA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 631
CYH A 674
HIS A 679
MET A 684
None
0.59A 2fqgA-5n4lA:
25.4
2fqgA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA601_0
(BLUE COPPER OXIDASE
CUEO)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 969
CYH A1015
HIS A1020
MET A1025
CU  A1102 (-3.0A)
CU  A1102 (-1.9A)
CU  A1102 (-3.2A)
CU  A1102 (-3.2A)
0.33A 2fqgA-5n4lA:
25.4
2fqgA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 101
HIS A 103
HIS A 972
HIS A 974
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
0.60A 2fqgA-5n4lA:
25.4
2fqgA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 972
HIS A 974
HIS A 101
HIS A 103
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
0.72A 2fqgA-5n4lA:
25.4
2fqgA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 12 PHE A 413
ILE A 441
ILE A 433
VAL A 351
HIS A 353
None
1.27A 2ft9A-5n4lA:
undetectable
2ft9A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_1
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 6 THR A 639
ASP A 665
THR A 666
ASP A 699
None
1.01A 2okcB-5n4lA:
undetectable
2okcB-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_A_CUA801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 HIS A 101
HIS A 160
HIS A 162
CU  A1105 (-3.1A)
CU  A1104 (-3.6A)
CU  A1101 (-3.3A)
0.73A 2oqeA-5n4lA:
undetectable
2oqeA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OQE_B_CUB801_0
(PEROXISOMAL COPPER
AMINE OXIDASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 HIS A 101
HIS A 160
HIS A 162
CU  A1105 (-3.1A)
CU  A1104 (-3.6A)
CU  A1101 (-3.3A)
0.73A 2oqeB-5n4lA:
undetectable
2oqeB-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 12 HIS A 103
HIS A 160
ILE A 169
HIS A1016
HIS A 972
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
None
CU  A1104 (-3.1A)
CU  A1105 (-3.3A)
1.02A 2pgrA-5n4lA:
undetectable
2pgrA-5n4lA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PGR_A_DCFA501_1
(ADENOSINE DEAMINASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 12 HIS A 162
HIS A 101
GLY A 975
HIS A 974
HIS A1014
CU  A1101 (-3.3A)
CU  A1105 (-3.1A)
None
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
1.13A 2pgrA-5n4lA:
undetectable
2pgrA-5n4lA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNC_A_CLUA808_1
(COPPER AMINE
OXIDASE, LIVER
ISOZYME)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 7 ALA A 114
TYR A 116
ASP A 127
HIS A 101
None
None
CA  A1106 (-2.6A)
CU  A1105 (-3.1A)
0.91A 2pncA-5n4lA:
undetectable
2pncA-5n4lA:
6.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q5K_A_AB1A201_2
(PROTEASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 12 ALA A 102
VAL A  88
ILE A  78
GLY A 175
ILE A 174
None
0.87A 2q5kB-5n4lA:
undetectable
2q5kB-5n4lA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1499_1
(CYTOCHROME P450 3A4)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 7 ILE A 356
THR A 361
ILE A 433
GLY A 427
None
0.83A 2v0mB-5n4lA:
undetectable
2v0mB-5n4lA:
10.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_A_CUA801_0
(COPPER AMINE OXIDASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 HIS A1014
HIS A1016
HIS A 972
CU  A1101 (-3.2A)
CU  A1104 (-3.1A)
CU  A1105 (-3.3A)
0.66A 2w0qA-5n4lA:
undetectable
2w0qA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W0Q_B_CUB801_0
(COPPER AMINE OXIDASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 HIS A 101
HIS A 160
HIS A 162
CU  A1105 (-3.1A)
CU  A1104 (-3.6A)
CU  A1101 (-3.3A)
0.70A 2w0qB-5n4lA:
undetectable
2w0qB-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_A_CUA154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 972
HIS A1016
HIS A1014
HIS A 103
CU  A1105 (-3.3A)
CU  A1104 (-3.1A)
CU  A1101 (-3.2A)
CU  A1104 ( 3.5A)
1.11A 2wkoA-5n4lA:
undetectable
2wkoA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAT_A_CLMA301_0
(XENOBIOTIC
ACETYLTRANSFERASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 GLY A 600
TYR A 365
SER A 597
None
0.72A 2xatA-5n4lA:
undetectable
2xatA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1337_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 631
CYH A 674
HIS A 679
MET A 684
None
0.68A 2xxgA-5n4lA:
13.2
2xxgA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_A_CUA1337_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 969
CYH A1015
HIS A1020
MET A1025
CU  A1102 (-3.0A)
CU  A1102 (-1.9A)
CU  A1102 (-3.2A)
CU  A1102 (-3.2A)
0.46A 2xxgA-5n4lA:
13.2
2xxgA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 631
CYH A 674
HIS A 679
MET A 684
None
0.64A 2xxgC-5n4lA:
9.7
2xxgC-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XXG_C_CUC1338_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 969
CYH A1015
HIS A1020
MET A1025
CU  A1102 (-3.0A)
CU  A1102 (-1.9A)
CU  A1102 (-3.2A)
CU  A1102 (-3.2A)
0.47A 2xxgC-5n4lA:
9.7
2xxgC-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_D_ADND504_1
(UNCHARACTERIZED
CONSERVED PROTEIN)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 PHE A 742
ASN A 740
PHE A 941
None
0.84A 2zbuD-5n4lA:
undetectable
2zbuD-5n4lA:
17.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BGD_B_PM6B302_1
(THIOPURINE
S-METHYLTRANSFERASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 7 PHE A 451
LEU A 566
LEU A 528
LEU A 403
None
0.80A 3bgdB-5n4lA:
undetectable
3bgdB-5n4lA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUR_A_TESA339_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 10 TYR A 832
ILE A 711
TYR A 759
THR A 816
VAL A 814
None
1.36A 3burA-5n4lA:
undetectable
3burA-5n4lA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUR_B_TESB340_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 10 TYR A 832
ILE A 711
TYR A 759
THR A 816
VAL A 814
None
1.36A 3burB-5n4lA:
undetectable
3burB-5n4lA:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWC_B_SAMB501_1
(SPERMIDINE SYNTHASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 GLN A 329
GLN A 319
ASP A  29
THR A 521
None
1.45A 3bwcB-5n4lA:
undetectable
3bwcB-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL4_A_ROCA100_2
(PROTEASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 9 ALA A 811
VAL A 797
ILE A 787
GLY A 870
ILE A 869
None
1.25A 3el4B-5n4lA:
undetectable
3el4B-5n4lA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA150_0
(ILEAL BILE
ACID-BINDING PROTEIN)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 12 ASN A 243
MET A 200
PHE A 266
ILE A 174
TYR A 159
None
0.78A 3em0A-5n4lA:
undetectable
3em0A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB150_0
(ILEAL BILE
ACID-BINDING PROTEIN)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 12 ASN A 243
MET A 200
PHE A 266
LEU A  52
ILE A 174
None
0.79A 3em0B-5n4lA:
undetectable
3em0B-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGI_A_BEZA284_0
(CATECHOL
1,2-DIOXYGENASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 12 ASP A 164
VAL A 163
PRO A 166
HIS A 974
HIS A1014
None
None
None
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
1.36A 3hgiA-5n4lA:
undetectable
3hgiA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 LEU A1012
HIS A 103
HIS A 160
HIS A1016
None
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
CU  A1104 (-3.1A)
0.93A 3kecA-5n4lA:
undetectable
3kecA-5n4lA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LJG_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 ILE A 158
HIS A 162
HIS A 974
HIS A1014
None
CU  A1101 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
0.95A 3ljgA-5n4lA:
undetectable
3ljgA-5n4lA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZV_A_017A200_2
(HIV-1 PROTEASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 11 ALA A 102
VAL A  88
ILE A  78
GLY A 175
ILE A 174
None
0.98A 3lzvB-5n4lA:
undetectable
3lzvB-5n4lA:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA357_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 HIS A1014
HIS A 972
HIS A 974
CU  A1101 (-3.2A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
0.82A 3mihA-5n4lA:
undetectable
3mihA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_1
(PROTEASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 10 ALA A 102
VAL A  88
ILE A  78
GLY A 175
ILE A 174
None
1.00A 3nu6A-5n4lA:
undetectable
3nu6A-5n4lA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUJ_B_478B401_1
(PROTEASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 10 ALA A 102
VAL A  88
ILE A  78
GLY A 175
ILE A 174
None
0.95A 3nujA-5n4lA:
undetectable
3nujA-5n4lA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P6H_A_IBPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 7 ILE A 836
VAL A 795
ARG A 707
TYR A 709
None
0.66A 3p6hA-5n4lA:
undetectable
3p6hA-5n4lA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_3
(PROTEASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 12 ALA A 102
VAL A  88
ILE A  78
GLY A 175
ILE A 174
None
0.94A 3pwrB-5n4lA:
undetectable
3pwrB-5n4lA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA601_0
(LACCASE-1)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 162
ILE A1021
HIS A1014
LEU A1012
CU  A1101 (-3.3A)
None
CU  A1101 (-3.2A)
None
1.33A 3qpkA-5n4lA:
11.0
3qpkA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA601_0
(LACCASE-1)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 275
CYH A 318
HIS A 323
LEU A 328
CU  A1103 (-3.3A)
CU  A1103 (-2.1A)
CU  A1103 (-3.0A)
CU  A1103 (-4.4A)
0.53A 3qpkA-5n4lA:
11.0
3qpkA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA602_0
(LACCASE-1)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 HIS A 162
HIS A 974
HIS A1014
CU  A1101 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
0.45A 3qpkA-5n4lA:
11.0
3qpkA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA602_0
(LACCASE-1)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 HIS A1016
HIS A 103
HIS A 160
CU  A1104 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
0.35A 3qpkA-5n4lA:
11.0
3qpkA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA604_0
(LACCASE-1)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 101
HIS A 103
HIS A 972
HIS A 974
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
0.60A 3qpkA-5n4lA:
11.0
3qpkA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA604_0
(LACCASE-1)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 972
HIS A 974
HIS A 101
HIS A 103
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
0.75A 3qpkA-5n4lA:
11.0
3qpkA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB602_0
(LACCASE-1)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 HIS A 162
HIS A 974
HIS A1014
CU  A1101 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
0.45A 3qpkB-5n4lA:
21.2
3qpkB-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB602_0
(LACCASE-1)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 HIS A1016
HIS A 103
HIS A 160
CU  A1104 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
0.36A 3qpkB-5n4lA:
21.2
3qpkB-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB604_0
(LACCASE-1)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 101
HIS A 103
HIS A 972
HIS A 974
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
0.57A 3qpkB-5n4lA:
21.2
3qpkB-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB604_0
(LACCASE-1)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 972
HIS A 974
HIS A 101
HIS A 103
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
0.73A 3qpkB-5n4lA:
21.2
3qpkB-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RUN_A_CCSA165_0
(LYSOZYME)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 ASN A 447
ALA A 358
LYS A 448
None
0.97A 3runA-5n4lA:
undetectable
3runA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S8P_B_SAMB500_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 HIS A 596
SER A 623
ASN A 626
None
0.70A 3s8pB-5n4lA:
undetectable
3s8pB-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_2
(HIV-1 PROTEASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 12 ALA A 102
VAL A  88
ILE A  78
GLY A 175
ILE A 174
None
0.91A 3so9B-5n4lA:
undetectable
3so9B-5n4lA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SPK_B_TPVB100_2
(HIV-1 PROTEASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 12 ALA A 102
VAL A  88
ILE A  78
GLY A 175
ILE A 174
None
1.03A 3spkB-5n4lA:
undetectable
3spkB-5n4lA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3C_A_017A201_2
(HIV-1 PROTEASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 10 ALA A 102
VAL A  88
ILE A  78
GLY A 175
ILE A 174
None
1.02A 3t3cB-5n4lA:
undetectable
3t3cB-5n4lA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_C_ADNC301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 9 ALA A  69
GLY A  72
LEU A 199
LEU A 250
ILE A 242
None
1.11A 3wdmC-5n4lA:
undetectable
3wdmC-5n4lA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 8 LEU A 893
HIS A 101
TYR A1029
HIS A 160
None
CU  A1105 (-3.1A)
None
CU  A1104 (-3.6A)
1.23A 3wg7C-5n4lA:
undetectable
3wg7N-5n4lA:
undetectable
3wg7P-5n4lA:
undetectable
3wg7C-5n4lA:
undetectable
3wg7N-5n4lA:
undetectable
3wg7P-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A3P_A_ACTA1223_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 ASP A 118
THR A1028
GLU A 112
LYS A 109
CA  A1106 (-4.3A)
None
CA  A1106 (-4.7A)
CA  A1106 (-4.4A)
1.36A 4a3pA-5n4lA:
undetectable
4a3pA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 11 THR A 558
ALA A 557
LEU A 652
ASN A 599
VAL A 432
None
1.25A 4claA-5n4lA:
undetectable
4claA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1001_0
(BLUE COPPER OXIDASE
CUEO)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 631
CYH A 674
HIS A 679
MET A 684
None
0.59A 4ef3A-5n4lA:
25.3
4ef3A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1001_0
(BLUE COPPER OXIDASE
CUEO)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 969
CYH A1015
HIS A1020
MET A1025
CU  A1102 (-3.0A)
CU  A1102 (-1.9A)
CU  A1102 (-3.2A)
CU  A1102 (-3.2A)
0.32A 4ef3A-5n4lA:
25.3
4ef3A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1002_0
(BLUE COPPER OXIDASE
CUEO)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 103
HIS A 160
HIS A 972
HIS A1016
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
CU  A1105 (-3.3A)
CU  A1104 (-3.1A)
0.74A 4ef3A-5n4lA:
25.4
4ef3A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1002_0
(BLUE COPPER OXIDASE
CUEO)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 974
HIS A1014
HIS A 101
HIS A 162
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
CU  A1105 (-3.1A)
CU  A1101 (-3.3A)
0.72A 4ef3A-5n4lA:
25.4
4ef3A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1003_0
(BLUE COPPER OXIDASE
CUEO)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 5 HIS A 101
HIS A 162
HIS A 972
HIS A 974
HIS A1014
CU  A1105 (-3.1A)
CU  A1101 (-3.3A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
0.44A 4ef3A-5n4lA:
25.4
4ef3A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1003_0
(BLUE COPPER OXIDASE
CUEO)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 5 HIS A 972
HIS A1016
HIS A 101
HIS A 103
HIS A 160
CU  A1105 (-3.3A)
CU  A1104 (-3.1A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
0.57A 4ef3A-5n4lA:
25.4
4ef3A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1003_0
(BLUE COPPER OXIDASE
CUEO)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 5 HIS A 974
HIS A 972
HIS A 160
HIS A 101
HIS A 103
CU  A1101 ( 3.2A)
CU  A1105 (-3.3A)
CU  A1104 (-3.6A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
1.40A 4ef3A-5n4lA:
25.4
4ef3A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1003_0
(BLUE COPPER OXIDASE
CUEO)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 5 HIS A1014
HIS A 972
HIS A 162
HIS A 974
HIS A 101
CU  A1101 (-3.2A)
CU  A1105 (-3.3A)
CU  A1101 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1105 (-3.1A)
1.39A 4ef3A-5n4lA:
25.4
4ef3A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1004_0
(BLUE COPPER OXIDASE
CUEO)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 101
HIS A 103
HIS A 972
HIS A 974
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
0.61A 4ef3A-5n4lA:
25.4
4ef3A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1004_0
(BLUE COPPER OXIDASE
CUEO)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 972
HIS A 974
HIS A 101
HIS A 103
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
0.75A 4ef3A-5n4lA:
25.4
4ef3A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSE_A_H4BA804_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 7 ARG A 352
VAL A 460
TRP A 494
GLU A 493
None
1.45A 4jseA-5n4lA:
undetectable
4jseB-5n4lA:
undetectable
4jseA-5n4lA:
12.14
4jseB-5n4lA:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 7 VAL A 460
ILE A 441
ARG A 352
ILE A 433
None
0.90A 4lv9B-5n4lA:
undetectable
4lv9B-5n4lA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_2
(TRANSPORTER)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 SER A 202
MET A 200
ASP A  15
None
0.90A 4mm4B-5n4lA:
undetectable
4mm4B-5n4lA:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_2
(TRANSPORTER)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 SER A 236
MET A 239
ASP A  29
NA  A1107 (-3.3A)
NA  A1107 ( 4.6A)
None
0.90A 4mm4B-5n4lA:
undetectable
4mm4B-5n4lA:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_B_29QB603_1
(TRANSPORTER)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 9 ASP A 364
GLY A 369
PHE A 389
SER A 399
GLY A 397
None
1.28A 4mmeB-5n4lA:
undetectable
4mmeB-5n4lA:
9.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_1
(PROTEASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 11 ALA A 102
VAL A  88
ILE A  78
GLY A 175
ILE A 174
None
0.97A 4njtA-5n4lA:
undetectable
4njtA-5n4lA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_A_TPVA500_1
(PROTEASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 12 ALA A 102
VAL A  88
ILE A  78
GLY A 175
ILE A 174
None
1.02A 4njuA-5n4lA:
undetectable
4njuA-5n4lA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJU_C_TPVC500_1
(PROTEASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 12 ALA A 102
VAL A  88
ILE A  78
GLY A 175
ILE A 174
None
1.02A 4njuC-5n4lA:
undetectable
4njuC-5n4lA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA305_1
(TYROSINASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 7 HIS A 974
HIS A 103
HIS A 160
ALA A 165
CU  A1101 ( 3.2A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
None
0.84A 4p6sA-5n4lA:
undetectable
4p6sA-5n4lA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PTJ_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 ASP A 570
LYS A 402
LEU A 528
None
1.00A 4ptjA-5n4lA:
undetectable
4ptjA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5H_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 12 ILE A 524
THR A 469
ILE A  26
LEU A 324
THR A 526
None
1.12A 4x5hA-5n4lA:
undetectable
4x5hA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_A_1N1A601_2
(TYROSINE-PROTEIN
KINASE ABL1)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 MET A 728
ASP A 744
PHE A 742
None
0.86A 4xeyA-5n4lA:
undetectable
4xeyA-5n4lA:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_B_1N1B601_2
(TYROSINE-PROTEIN
KINASE ABL1)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 MET A 728
ASP A 744
PHE A 742
None
0.92A 4xeyB-5n4lA:
undetectable
4xeyB-5n4lA:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_A_29SA601_1
(ESTROGEN RECEPTOR)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 12 ASP A 128
LEU A 733
ARG A  96
HIS A1016
PRO A 117
CA  A1106 (-2.2A)
None
None
CU  A1104 (-3.1A)
None
1.05A 4xi3A-5n4lA:
undetectable
4xi3A-5n4lA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP9_C_1WEC706_1
(TRANSPORTER)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 PHE A 670
ASP A 671
GLY A 668
SER A 636
None
1.43A 4xp9C-5n4lA:
undetectable
4xp9C-5n4lA:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XPB_A_COCA702_1
(TRANSPORTER)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 10 ASP A 364
GLY A 369
PHE A 389
SER A 399
GLY A 397
None
1.33A 4xpbA-5n4lA:
undetectable
4xpbA-5n4lA:
10.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 12 GLY A 632
LEU A 894
PHE A 898
GLY A 867
THR A 676
None
1.00A 4ze1A-5n4lA:
undetectable
4ze1A-5n4lA:
9.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZXI_A_GLYA1402_0
(TYROCIDINE
SYNTHETASE 3)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 7 ILE A   7
GLY A  75
THR A  10
LYS A  67
None
1.09A 4zxiA-5n4lA:
undetectable
4zxiA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 HIS A 596
SER A 623
ASN A 626
None
0.68A 5cprB-5n4lA:
undetectable
5cprB-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CR1_A_T44A201_1
(TRANSTHYRETIN)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 LYS A 656
LEU A 658
LEU A 621
VAL A 630
None
1.12A 5cr1A-5n4lA:
undetectable
5cr1A-5n4lA:
26.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 GLU A  11
TRP A 210
ASN A  92
None
0.92A 5dv4A-5n4lA:
undetectable
5dv4A-5n4lA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_2
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 GLU A 715
TRP A 904
ASN A 801
None
0.95A 5dv4A-5n4lA:
undetectable
5dv4A-5n4lA:
13.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 6 PHE A 560
SER A 623
ALA A 624
HIS A 631
None
1.27A 5dzkB-5n4lA:
undetectable
5dzkP-5n4lA:
undetectable
5dzkB-5n4lA:
undetectable
5dzkP-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_U_BEZU801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 6 PHE A 560
SER A 623
ALA A 624
HIS A 631
None
1.26A 5dzkg-5n4lA:
undetectable
5dzku-5n4lA:
undetectable
5dzkg-5n4lA:
undetectable
5dzku-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 12 ILE A 524
THR A 469
ILE A  26
LEU A 324
THR A 526
None
1.14A 5e8qB-5n4lA:
undetectable
5e8qB-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 ARG A 839
VAL A 874
TRP A 852
None
1.17A 5fvoA-5n4lA:
undetectable
5fvoA-5n4lA:
12.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWZ_D_010D6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
PEDV MAIN PROTEASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 MET A 962
HIS A 812
GLY A 632
None
0.77A 5gwzB-5n4lA:
undetectable
5gwzB-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_A_HQEA303_1
(TYROSINASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 7 HIS A 974
HIS A 103
HIS A 160
ALA A 165
CU  A1101 ( 3.2A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
None
0.84A 5i3aA-5n4lA:
undetectable
5i3aA-5n4lA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3A_B_HQEB304_1
(TYROSINASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 7 HIS A 974
HIS A 103
HIS A 160
ALA A 165
CU  A1101 ( 3.2A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
None
0.85A 5i3aB-5n4lA:
undetectable
5i3aB-5n4lA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_A_HQEA303_1
(TYROSINASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 7 HIS A 974
HIS A 103
HIS A 160
ALA A 165
CU  A1101 ( 3.2A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
None
0.85A 5i3bA-5n4lA:
undetectable
5i3bA-5n4lA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 160
HIS A 103
HIS A1014
ALA A 165
CU  A1104 (-3.6A)
CU  A1104 ( 3.5A)
CU  A1101 (-3.2A)
None
1.23A 5i3bB-5n4lA:
undetectable
5i3bB-5n4lA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3B_B_HQEB303_1
(TYROSINASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 162
HIS A 974
HIS A1016
ALA A 165
CU  A1101 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1104 (-3.1A)
None
1.38A 5i3bB-5n4lA:
undetectable
5i3bB-5n4lA:
14.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKW_A_TESA601_1
(AROMATASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 11 ILE A 711
PHE A 799
ILE A 787
VAL A 714
LEU A 868
None
1.04A 5jkwA-5n4lA:
undetectable
5jkwA-5n4lA:
9.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KF8_A_GCSA404_1
(PREDICTED
ACETYLTRANSFERASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 8 GLU A 465
GLY A 475
ASP A 474
TRP A 314
None
1.10A 5kf8A-5n4lA:
undetectable
5kf8A-5n4lA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_A_GCSA407_1
(PREDICTED
ACETYLTRANSFERASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 8 GLU A 465
GLY A 475
ASP A 474
TRP A 314
None
1.10A 5kgpA-5n4lA:
undetectable
5kgpA-5n4lA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KGP_B_GCSB405_1
(PREDICTED
ACETYLTRANSFERASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 8 GLU A 465
GLY A 475
ASP A 474
TRP A 314
None
1.10A 5kgpB-5n4lA:
undetectable
5kgpB-5n4lA:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_A_ASCA1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 6 VAL A 163
TYR A  98
ARG A  96
GLN A 736
None
1.29A 5kkzA-5n4lA:
undetectable
5kkzG-5n4lA:
0.0
5kkzA-5n4lA:
undetectable
5kkzG-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KKZ_O_ASCO1004_0
(CYTOCHROME B
UBIQUINOL-CYTOCHROME
C REDUCTASE
IRON-SULFUR SUBUNIT)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 7 VAL A 163
TYR A  98
ARG A  96
GLN A 736
None
1.26A 5kkzM-5n4lA:
undetectable
5kkzO-5n4lA:
undetectable
5kkzM-5n4lA:
undetectable
5kkzO-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_A_MMSA514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 10 HIS A1014
HIS A 974
TYR A 107
HIS A 103
HIS A 160
CU  A1101 (-3.2A)
CU  A1101 ( 3.2A)
None
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
1.29A 5m8nA-5n4lA:
undetectable
5m8nA-5n4lA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8N_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 9 HIS A1014
HIS A 974
TYR A 107
HIS A 103
HIS A 160
CU  A1101 (-3.2A)
CU  A1101 ( 3.2A)
None
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
1.35A 5m8nC-5n4lA:
undetectable
5m8nC-5n4lA:
11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA501_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 5 HIS A 101
HIS A 162
HIS A 972
HIS A 974
HIS A1014
CU  A1105 (-3.1A)
CU  A1101 (-3.3A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
0.37A 5mejA-5n4lA:
11.9
5mejA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA501_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 5 HIS A 972
HIS A1016
HIS A 101
HIS A 103
HIS A 160
CU  A1105 (-3.3A)
CU  A1104 (-3.1A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
0.60A 5mejA-5n4lA:
11.9
5mejA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA501_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 5 HIS A1014
HIS A 972
HIS A 162
HIS A 974
HIS A 101
CU  A1101 (-3.2A)
CU  A1105 (-3.3A)
CU  A1101 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1105 (-3.1A)
1.31A 5mejA-5n4lA:
11.9
5mejA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA502_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 6 HIS A 101
HIS A 103
HIS A 160
HIS A 972
HIS A1016
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
CU  A1105 (-3.3A)
CU  A1104 (-3.1A)
0.68A 5mejA-5n4lA:
11.9
5mejA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA502_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 6 HIS A 972
HIS A 974
HIS A1014
HIS A 101
HIS A 162
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
CU  A1105 (-3.1A)
CU  A1101 (-3.3A)
0.71A 5mejA-5n4lA:
11.9
5mejA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA502_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 6 HIS A 972
HIS A1016
HIS A 101
HIS A 160
CU  A1105 (-3.3A)
CU  A1104 (-3.1A)
CU  A1105 (-3.1A)
CU  A1104 (-3.6A)
0.71A 5mejA-5n4lA:
11.9
5mejA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA503_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 101
HIS A 103
HIS A 972
HIS A 974
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
0.59A 5mejA-5n4lA:
11.9
5mejA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA503_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 972
HIS A 974
HIS A 101
HIS A 103
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
0.72A 5mejA-5n4lA:
11.9
5mejA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA501_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 5 HIS A 101
HIS A 162
HIS A 972
HIS A 974
HIS A1014
CU  A1105 (-3.1A)
CU  A1101 (-3.3A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
0.36A 5mewA-5n4lA:
11.8
5mewA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA501_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 5 HIS A 972
HIS A1016
HIS A 101
HIS A 103
HIS A 160
CU  A1105 (-3.3A)
CU  A1104 (-3.1A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
0.58A 5mewA-5n4lA:
11.8
5mewA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA501_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 5 HIS A1014
HIS A 972
HIS A 162
HIS A 974
HIS A 101
CU  A1101 (-3.2A)
CU  A1105 (-3.3A)
CU  A1101 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1105 (-3.1A)
1.31A 5mewA-5n4lA:
11.8
5mewA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA502_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 6 HIS A 101
HIS A 103
HIS A 160
HIS A 972
HIS A1016
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
CU  A1105 (-3.3A)
CU  A1104 (-3.1A)
0.67A 5mewA-5n4lA:
10.8
5mewA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA502_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 6 HIS A 972
HIS A 974
HIS A1014
HIS A 101
HIS A 162
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
CU  A1105 (-3.1A)
CU  A1101 (-3.3A)
0.71A 5mewA-5n4lA:
10.8
5mewA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA502_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 6 HIS A 972
HIS A1016
HIS A 101
HIS A 160
CU  A1105 (-3.3A)
CU  A1104 (-3.1A)
CU  A1105 (-3.1A)
CU  A1104 (-3.6A)
0.71A 5mewA-5n4lA:
10.8
5mewA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA503_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 101
HIS A 103
HIS A 972
HIS A 974
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
0.59A 5mewA-5n4lA:
10.8
5mewA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA503_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 972
HIS A 974
HIS A 101
HIS A 103
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
0.72A 5mewA-5n4lA:
10.8
5mewA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA501_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 5 HIS A 101
HIS A 162
HIS A 972
HIS A 974
HIS A1014
CU  A1105 (-3.1A)
CU  A1101 (-3.3A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
0.36A 5mhuA-5n4lA:
11.7
5mhuA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA501_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 5 HIS A 972
HIS A1016
HIS A 101
HIS A 103
HIS A 160
CU  A1105 (-3.3A)
CU  A1104 (-3.1A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
0.58A 5mhuA-5n4lA:
11.7
5mhuA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA501_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 5 HIS A1014
HIS A 972
HIS A 162
HIS A 974
HIS A 101
CU  A1101 (-3.2A)
CU  A1105 (-3.3A)
CU  A1101 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1105 (-3.1A)
1.31A 5mhuA-5n4lA:
11.7
5mhuA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA502_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 6 HIS A 101
HIS A 103
HIS A 160
HIS A 972
HIS A1016
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
CU  A1105 (-3.3A)
CU  A1104 (-3.1A)
0.66A 5mhuA-5n4lA:
10.7
5mhuA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA502_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 6 HIS A 972
HIS A 974
HIS A1014
HIS A 101
HIS A 162
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
CU  A1105 (-3.1A)
CU  A1101 (-3.3A)
0.72A 5mhuA-5n4lA:
10.7
5mhuA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA502_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 6 HIS A 972
HIS A1016
HIS A 101
HIS A 160
CU  A1105 (-3.3A)
CU  A1104 (-3.1A)
CU  A1105 (-3.1A)
CU  A1104 (-3.6A)
0.71A 5mhuA-5n4lA:
10.7
5mhuA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA503_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 101
HIS A 103
HIS A 972
HIS A 974
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
0.58A 5mhuA-5n4lA:
10.7
5mhuA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA503_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 972
HIS A 974
HIS A 101
HIS A 103
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
0.71A 5mhuA-5n4lA:
10.7
5mhuA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA501_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 5 HIS A 101
HIS A 162
HIS A 972
HIS A 974
HIS A1014
CU  A1105 (-3.1A)
CU  A1101 (-3.3A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
0.36A 5mhvA-5n4lA:
11.3
5mhvA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA501_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 5 HIS A 972
HIS A1016
HIS A 101
HIS A 103
HIS A 160
CU  A1105 (-3.3A)
CU  A1104 (-3.1A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
0.58A 5mhvA-5n4lA:
11.3
5mhvA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA501_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 5 HIS A1014
HIS A 972
HIS A 162
HIS A 974
HIS A 101
CU  A1101 (-3.2A)
CU  A1105 (-3.3A)
CU  A1101 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1105 (-3.1A)
1.32A 5mhvA-5n4lA:
11.3
5mhvA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA502_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 6 HIS A 101
HIS A 103
HIS A 160
HIS A 972
HIS A1016
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
CU  A1105 (-3.3A)
CU  A1104 (-3.1A)
0.66A 5mhvA-5n4lA:
11.3
5mhvA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA502_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 6 HIS A 972
HIS A 974
HIS A1014
HIS A 101
HIS A 162
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
CU  A1105 (-3.1A)
CU  A1101 (-3.3A)
0.72A 5mhvA-5n4lA:
11.3
5mhvA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA502_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 6 HIS A 972
HIS A1016
HIS A 101
HIS A 160
CU  A1105 (-3.3A)
CU  A1104 (-3.1A)
CU  A1105 (-3.1A)
CU  A1104 (-3.6A)
0.70A 5mhvA-5n4lA:
11.3
5mhvA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA503_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 101
HIS A 103
HIS A 972
HIS A 974
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
0.58A 5mhvA-5n4lA:
11.3
5mhvA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA503_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 972
HIS A 974
HIS A 101
HIS A 103
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
0.72A 5mhvA-5n4lA:
11.3
5mhvA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA601_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 162
HIS A 972
HIS A 974
HIS A1014
CU  A1101 (-3.3A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
0.31A 5mhwA-5n4lA:
12.6
5mhwA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA601_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A1016
HIS A 101
HIS A 103
HIS A 160
CU  A1104 (-3.1A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
0.59A 5mhwA-5n4lA:
12.6
5mhwA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 101
HIS A 103
HIS A 160
HIS A1016
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
CU  A1104 (-3.1A)
0.71A 5mhwA-5n4lA:
12.6
5mhwA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 160
HIS A 162
HIS A 101
HIS A 974
CU  A1104 (-3.6A)
CU  A1101 (-3.3A)
CU  A1105 (-3.1A)
CU  A1101 ( 3.2A)
1.05A 5mhwA-5n4lA:
12.6
5mhwA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 972
HIS A 974
HIS A1014
HIS A 162
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
CU  A1101 (-3.3A)
0.76A 5mhwA-5n4lA:
12.6
5mhwA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A1016
HIS A 972
HIS A1014
HIS A 974
CU  A1104 (-3.1A)
CU  A1105 (-3.3A)
CU  A1101 (-3.2A)
CU  A1101 ( 3.2A)
0.95A 5mhwA-5n4lA:
12.6
5mhwA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA603_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 101
HIS A 103
HIS A 972
HIS A 974
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
0.58A 5mhwA-5n4lA:
11.3
5mhwA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA603_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 972
HIS A 974
HIS A 101
HIS A 103
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
0.72A 5mhwA-5n4lA:
11.3
5mhwA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA601_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 162
HIS A 972
HIS A 974
HIS A1014
CU  A1101 (-3.3A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
0.32A 5mhxA-5n4lA:
11.8
5mhxA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA601_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A1016
HIS A 101
HIS A 103
HIS A 160
CU  A1104 (-3.1A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
0.60A 5mhxA-5n4lA:
11.8
5mhxA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 101
HIS A 103
HIS A 160
HIS A1016
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
CU  A1104 (-3.1A)
0.70A 5mhxA-5n4lA:
11.8
5mhxA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 160
HIS A 162
HIS A 101
HIS A 974
CU  A1104 (-3.6A)
CU  A1101 (-3.3A)
CU  A1105 (-3.1A)
CU  A1101 ( 3.2A)
1.05A 5mhxA-5n4lA:
11.8
5mhxA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 972
HIS A 974
HIS A1014
HIS A 162
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
CU  A1101 (-3.3A)
0.76A 5mhxA-5n4lA:
11.8
5mhxA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A1016
HIS A 972
HIS A1014
HIS A 974
CU  A1104 (-3.1A)
CU  A1105 (-3.3A)
CU  A1101 (-3.2A)
CU  A1101 ( 3.2A)
0.95A 5mhxA-5n4lA:
11.8
5mhxA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA603_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 101
HIS A 103
HIS A 972
HIS A 974
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
0.57A 5mhxA-5n4lA:
10.3
5mhxA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA603_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 972
HIS A 974
HIS A 101
HIS A 103
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
0.71A 5mhxA-5n4lA:
10.3
5mhxA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA601_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 162
HIS A 972
HIS A 974
HIS A1014
CU  A1101 (-3.3A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
0.32A 5mhyA-5n4lA:
25.1
5mhyA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA601_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A1016
HIS A 101
HIS A 103
HIS A 160
CU  A1104 (-3.1A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
0.59A 5mhyA-5n4lA:
25.1
5mhyA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 101
HIS A 103
HIS A 160
HIS A1016
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
CU  A1104 (-3.1A)
0.70A 5mhyA-5n4lA:
25.1
5mhyA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 160
HIS A 162
HIS A 101
HIS A 974
CU  A1104 (-3.6A)
CU  A1101 (-3.3A)
CU  A1105 (-3.1A)
CU  A1101 ( 3.2A)
1.05A 5mhyA-5n4lA:
25.1
5mhyA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 972
HIS A 974
HIS A1014
HIS A 162
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
CU  A1101 (-3.3A)
0.77A 5mhyA-5n4lA:
25.1
5mhyA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A1016
HIS A 972
HIS A1014
HIS A 974
CU  A1104 (-3.1A)
CU  A1105 (-3.3A)
CU  A1101 (-3.2A)
CU  A1101 ( 3.2A)
0.95A 5mhyA-5n4lA:
25.1
5mhyA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA603_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 101
HIS A 103
HIS A 972
HIS A 974
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
0.57A 5mhyA-5n4lA:
25.0
5mhyA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA603_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 972
HIS A 974
HIS A 101
HIS A 103
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
0.71A 5mhyA-5n4lA:
25.0
5mhyA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA601_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 162
HIS A 972
HIS A 974
HIS A1014
CU  A1101 (-3.3A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
0.32A 5mhzA-5n4lA:
12.6
5mhzA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA601_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A1016
HIS A 101
HIS A 103
HIS A 160
CU  A1104 (-3.1A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
0.59A 5mhzA-5n4lA:
12.6
5mhzA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 101
HIS A 103
HIS A 160
HIS A1016
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
CU  A1104 (-3.1A)
0.70A 5mhzA-5n4lA:
12.6
5mhzA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 160
HIS A 162
HIS A 101
HIS A 974
CU  A1104 (-3.6A)
CU  A1101 (-3.3A)
CU  A1105 (-3.1A)
CU  A1101 ( 3.2A)
1.05A 5mhzA-5n4lA:
12.6
5mhzA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 972
HIS A 974
HIS A1014
HIS A 162
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
CU  A1101 (-3.3A)
0.77A 5mhzA-5n4lA:
12.6
5mhzA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A1016
HIS A 972
HIS A1014
HIS A 974
CU  A1104 (-3.1A)
CU  A1105 (-3.3A)
CU  A1101 (-3.2A)
CU  A1101 ( 3.2A)
0.95A 5mhzA-5n4lA:
12.6
5mhzA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA603_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 101
HIS A 103
HIS A 972
HIS A 974
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
0.58A 5mhzA-5n4lA:
11.4
5mhzA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA603_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 972
HIS A 974
HIS A 101
HIS A 103
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
0.72A 5mhzA-5n4lA:
11.4
5mhzA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA601_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 162
HIS A 972
HIS A 974
HIS A1014
CU  A1101 (-3.3A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
0.32A 5mi1A-5n4lA:
11.8
5mi1A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA601_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A1016
HIS A 101
HIS A 103
HIS A 160
CU  A1104 (-3.1A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
0.59A 5mi1A-5n4lA:
11.8
5mi1A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 101
HIS A 103
HIS A 160
HIS A1016
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
CU  A1104 (-3.1A)
0.70A 5mi1A-5n4lA:
11.8
5mi1A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 160
HIS A 162
HIS A 101
HIS A 974
CU  A1104 (-3.6A)
CU  A1101 (-3.3A)
CU  A1105 (-3.1A)
CU  A1101 ( 3.2A)
1.05A 5mi1A-5n4lA:
11.8
5mi1A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 972
HIS A 974
HIS A1014
HIS A 162
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
CU  A1101 (-3.3A)
0.77A 5mi1A-5n4lA:
11.8
5mi1A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A1016
HIS A 972
HIS A1014
HIS A 974
CU  A1104 (-3.1A)
CU  A1105 (-3.3A)
CU  A1101 (-3.2A)
CU  A1101 ( 3.2A)
0.95A 5mi1A-5n4lA:
11.8
5mi1A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA603_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 101
HIS A 103
HIS A 972
HIS A 974
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
0.57A 5mi1A-5n4lA:
10.7
5mi1A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA603_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 972
HIS A 974
HIS A 101
HIS A 103
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
0.71A 5mi1A-5n4lA:
10.7
5mi1A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA601_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 162
HIS A 972
HIS A 974
HIS A1014
CU  A1101 (-3.3A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
0.32A 5mi2A-5n4lA:
11.8
5mi2A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA601_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A1016
HIS A 101
HIS A 103
HIS A 160
CU  A1104 (-3.1A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
0.59A 5mi2A-5n4lA:
11.8
5mi2A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 101
HIS A 103
HIS A 160
HIS A1016
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
CU  A1104 (-3.1A)
0.70A 5mi2A-5n4lA:
11.8
5mi2A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 160
HIS A 162
HIS A 101
HIS A 974
CU  A1104 (-3.6A)
CU  A1101 (-3.3A)
CU  A1105 (-3.1A)
CU  A1101 ( 3.2A)
1.05A 5mi2A-5n4lA:
11.8
5mi2A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 972
HIS A 974
HIS A1014
HIS A 162
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
CU  A1101 (-3.3A)
0.77A 5mi2A-5n4lA:
11.8
5mi2A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A1016
HIS A 972
HIS A1014
HIS A 974
CU  A1104 (-3.1A)
CU  A1105 (-3.3A)
CU  A1101 (-3.2A)
CU  A1101 ( 3.2A)
0.94A 5mi2A-5n4lA:
11.8
5mi2A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA603_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 101
HIS A 103
HIS A 972
HIS A 974
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
0.57A 5mi2A-5n4lA:
10.3
5mi2A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA603_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 972
HIS A 974
HIS A 101
HIS A 103
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
0.71A 5mi2A-5n4lA:
10.3
5mi2A-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA601_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 162
HIS A 972
HIS A 974
HIS A1014
CU  A1101 (-3.3A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
0.33A 5miaA-5n4lA:
11.8
5miaA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA601_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A1016
HIS A 101
HIS A 103
HIS A 160
CU  A1104 (-3.1A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
0.59A 5miaA-5n4lA:
11.8
5miaA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 101
HIS A 103
HIS A 160
HIS A1016
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
CU  A1104 (-3.1A)
0.70A 5miaA-5n4lA:
11.8
5miaA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 160
HIS A 162
HIS A 101
HIS A 974
CU  A1104 (-3.6A)
CU  A1101 (-3.3A)
CU  A1105 (-3.1A)
CU  A1101 ( 3.2A)
1.05A 5miaA-5n4lA:
11.8
5miaA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 972
HIS A 974
HIS A1014
HIS A 162
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
CU  A1101 (-3.3A)
0.77A 5miaA-5n4lA:
11.8
5miaA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A1016
HIS A 972
HIS A1014
HIS A 974
CU  A1104 (-3.1A)
CU  A1105 (-3.3A)
CU  A1101 (-3.2A)
CU  A1101 ( 3.2A)
0.95A 5miaA-5n4lA:
11.8
5miaA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA603_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 101
HIS A 103
HIS A 972
HIS A 974
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
0.58A 5miaA-5n4lA:
10.8
5miaA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA603_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 972
HIS A 974
HIS A 101
HIS A 103
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
0.72A 5miaA-5n4lA:
10.8
5miaA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA601_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 162
HIS A 972
HIS A 974
HIS A1014
CU  A1101 (-3.3A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
0.33A 5mibA-5n4lA:
25.0
5mibA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA601_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A1016
HIS A 101
HIS A 103
HIS A 160
CU  A1104 (-3.1A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
0.59A 5mibA-5n4lA:
25.0
5mibA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 101
HIS A 103
HIS A 160
HIS A1016
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
CU  A1104 (-3.1A)
0.70A 5mibA-5n4lA:
11.8
5mibA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 160
HIS A 162
HIS A 101
HIS A 974
CU  A1104 (-3.6A)
CU  A1101 (-3.3A)
CU  A1105 (-3.1A)
CU  A1101 ( 3.2A)
1.05A 5mibA-5n4lA:
11.8
5mibA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 972
HIS A 974
HIS A1014
HIS A 162
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
CU  A1101 (-3.3A)
0.77A 5mibA-5n4lA:
11.8
5mibA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A1016
HIS A 972
HIS A1014
HIS A 974
CU  A1104 (-3.1A)
CU  A1105 (-3.3A)
CU  A1101 (-3.2A)
CU  A1101 ( 3.2A)
0.95A 5mibA-5n4lA:
11.8
5mibA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA603_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 101
HIS A 103
HIS A 972
HIS A 974
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
0.58A 5mibA-5n4lA:
10.5
5mibA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA603_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 972
HIS A 974
HIS A 101
HIS A 103
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
0.72A 5mibA-5n4lA:
10.5
5mibA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA601_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 162
HIS A 972
HIS A 974
HIS A1014
CU  A1101 (-3.3A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
0.33A 5micA-5n4lA:
11.8
5micA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA601_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A1016
HIS A 101
HIS A 103
HIS A 160
CU  A1104 (-3.1A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
0.59A 5micA-5n4lA:
11.8
5micA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 101
HIS A 103
HIS A 160
HIS A1016
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
CU  A1104 (-3.1A)
0.70A 5micA-5n4lA:
11.8
5micA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 160
HIS A 162
HIS A 101
HIS A 974
CU  A1104 (-3.6A)
CU  A1101 (-3.3A)
CU  A1105 (-3.1A)
CU  A1101 ( 3.2A)
1.05A 5micA-5n4lA:
11.8
5micA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 972
HIS A 974
HIS A1014
HIS A 162
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
CU  A1101 (-3.3A)
0.77A 5micA-5n4lA:
11.8
5micA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A1016
HIS A 972
HIS A1014
HIS A 974
CU  A1104 (-3.1A)
CU  A1105 (-3.3A)
CU  A1101 (-3.2A)
CU  A1101 ( 3.2A)
0.95A 5micA-5n4lA:
11.8
5micA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA603_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 101
HIS A 103
HIS A 972
HIS A 974
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
0.57A 5micA-5n4lA:
10.7
5micA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA603_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 972
HIS A 974
HIS A 101
HIS A 103
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
0.72A 5micA-5n4lA:
10.7
5micA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 162
HIS A 972
HIS A 974
HIS A1014
CU  A1101 (-3.3A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
0.33A 5midA-5n4lA:
25.0
5midA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA601_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A1016
HIS A 101
HIS A 103
HIS A 160
CU  A1104 (-3.1A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
0.59A 5midA-5n4lA:
25.0
5midA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 101
HIS A 103
HIS A 160
HIS A1016
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
CU  A1104 (-3.1A)
0.70A 5midA-5n4lA:
25.0
5midA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 160
HIS A 162
HIS A 101
HIS A 974
CU  A1104 (-3.6A)
CU  A1101 (-3.3A)
CU  A1105 (-3.1A)
CU  A1101 ( 3.2A)
1.05A 5midA-5n4lA:
25.0
5midA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 972
HIS A 974
HIS A1014
HIS A 162
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
CU  A1101 (-3.3A)
0.77A 5midA-5n4lA:
25.0
5midA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A1016
HIS A 972
HIS A1014
HIS A 974
CU  A1104 (-3.1A)
CU  A1105 (-3.3A)
CU  A1101 (-3.2A)
CU  A1101 ( 3.2A)
0.95A 5midA-5n4lA:
25.0
5midA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA603_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 101
HIS A 103
HIS A 972
HIS A 974
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
0.57A 5midA-5n4lA:
25.1
5midA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA603_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 972
HIS A 974
HIS A 101
HIS A 103
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
0.72A 5midA-5n4lA:
25.1
5midA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA601_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 162
HIS A 972
HIS A 974
HIS A1014
CU  A1101 (-3.3A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
0.33A 5mieA-5n4lA:
11.8
5mieA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA601_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A1016
HIS A 101
HIS A 103
HIS A 160
CU  A1104 (-3.1A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
0.58A 5mieA-5n4lA:
11.8
5mieA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 101
HIS A 103
HIS A 160
HIS A1016
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
CU  A1104 (-3.1A)
0.70A 5mieA-5n4lA:
11.8
5mieA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 160
HIS A 162
HIS A 101
HIS A 974
CU  A1104 (-3.6A)
CU  A1101 (-3.3A)
CU  A1105 (-3.1A)
CU  A1101 ( 3.2A)
1.05A 5mieA-5n4lA:
11.8
5mieA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 972
HIS A 974
HIS A1014
HIS A 162
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
CU  A1101 (-3.3A)
0.77A 5mieA-5n4lA:
11.8
5mieA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A1016
HIS A 972
HIS A1014
HIS A 974
CU  A1104 (-3.1A)
CU  A1105 (-3.3A)
CU  A1101 (-3.2A)
CU  A1101 ( 3.2A)
0.95A 5mieA-5n4lA:
11.8
5mieA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA603_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 101
HIS A 103
HIS A 972
HIS A 974
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
0.58A 5mieA-5n4lA:
10.8
5mieA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA603_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 972
HIS A 974
HIS A 101
HIS A 103
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
0.71A 5mieA-5n4lA:
10.8
5mieA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA601_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 HIS A 162
HIS A 974
HIS A1014
CU  A1101 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
0.33A 5migA-5n4lA:
11.8
5migA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA601_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 HIS A1016
HIS A 103
HIS A 160
CU  A1104 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
0.47A 5migA-5n4lA:
11.8
5migA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 101
HIS A 103
HIS A 160
HIS A1016
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1104 (-3.6A)
CU  A1104 (-3.1A)
0.69A 5migA-5n4lA:
11.8
5migA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 160
HIS A 162
HIS A 101
HIS A 974
CU  A1104 (-3.6A)
CU  A1101 (-3.3A)
CU  A1105 (-3.1A)
CU  A1101 ( 3.2A)
1.06A 5migA-5n4lA:
11.8
5migA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A 972
HIS A 974
HIS A1014
HIS A 162
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1101 (-3.2A)
CU  A1101 (-3.3A)
0.78A 5migA-5n4lA:
11.8
5migA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA602_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 HIS A1016
HIS A 972
HIS A1014
HIS A 974
CU  A1104 (-3.1A)
CU  A1105 (-3.3A)
CU  A1101 (-3.2A)
CU  A1101 ( 3.2A)
0.94A 5migA-5n4lA:
11.8
5migA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA603_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 101
HIS A 103
HIS A 972
HIS A 974
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
0.58A 5migA-5n4lA:
10.5
5migA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA603_0
(LACCASE 2)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 4 HIS A 972
HIS A 974
HIS A 101
HIS A 103
CU  A1105 (-3.3A)
CU  A1101 ( 3.2A)
CU  A1105 (-3.1A)
CU  A1104 ( 3.5A)
0.72A 5migA-5n4lA:
10.5
5migA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_D_SAMD301_0
(NS5)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 12 GLY A 369
GLY A 398
ASP A 570
ASP A 364
ILE A 362
None
0.93A 5njvD-5n4lA:
undetectable
5njvD-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB306_0
(WELO5)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 GLU A 673
ARG A 860
TYR A 680
None
0.40A 5trqB-5n4lA:
undetectable
5trqB-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_1
(GLUCOCORTICOID
RECEPTOR)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 TRP A 363
MET A 602
ASN A 605
None
1.19A 5uc1A-5n4lA:
undetectable
5uc1A-5n4lA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UJX_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 12 ILE A 524
THR A 469
ILE A  26
LEU A 324
THR A 526
None
1.13A 5ujxB-5n4lA:
undetectable
5ujxB-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 8 HIS A 101
TYR A1029
HIS A 160
LEU A 893
CU  A1105 (-3.1A)
None
CU  A1104 (-3.6A)
None
1.18A 5x19A-5n4lA:
undetectable
5x19C-5n4lA:
undetectable
5x19P-5n4lA:
undetectable
5x19A-5n4lA:
undetectable
5x19C-5n4lA:
undetectable
5x19P-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 7 HIS A 101
TYR A1029
HIS A 160
LEU A 893
CU  A1105 (-3.1A)
None
CU  A1104 (-3.6A)
None
1.22A 5x1fA-5n4lA:
undetectable
5x1fC-5n4lA:
undetectable
5x1fP-5n4lA:
undetectable
5x1fA-5n4lA:
undetectable
5x1fC-5n4lA:
undetectable
5x1fP-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA503_1
(CYTOCHROME P450 2C9)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 6 PHE A 994
PRO A 995
GLY A 996
THR A 997
None
0.57A 5x24A-5n4lA:
undetectable
5x24A-5n4lA:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 MET A 268
TYR A 159
GLY A 175
GLY A  75
None
0.96A 5x7pA-5n4lA:
undetectable
5x7pA-5n4lA:
4.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_A_ACRA1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 MET A 962
TYR A 854
GLY A 870
GLY A 784
None
1.20A 5x7pA-5n4lA:
undetectable
5x7pA-5n4lA:
4.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_B_SAMB505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 12 GLY A 600
TRP A 363
HIS A 679
CYH A 674
GLY A 682
None
1.31A 6bp4B-5n4lA:
undetectable
6bp4B-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BP4_B_SAMB505_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-9 SPECIFIC)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 12 GLY A 600
TRP A 363
HIS A 679
CYH A 674
GLY A 683
None
1.43A 6bp4B-5n4lA:
undetectable
6bp4B-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_A_RFPA502_1
(RIFAMPIN
MONOOXYGENASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 12 HIS A 103
LEU A 893
VAL A 959
PHE A 895
THR A 970
CU  A1104 ( 3.5A)
None
None
None
None
1.44A 6brdA-5n4lA:
undetectable
6brdA-5n4lA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CBZ_B_ESTB602_1
(ESTROGEN RECEPTOR)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 10 ALA A 277
LEU A 316
MET A 315
ILE A  26
LEU A 328
None
None
None
None
CU  A1103 (-4.4A)
1.33A 6cbzB-5n4lA:
undetectable
6cbzB-5n4lA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DCH_A_ACTA401_0
(SCOE PROTEIN)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 THR A 970
HIS A 972
ASP A 989
HIS A 103
None
CU  A1105 (-3.3A)
None
CU  A1104 ( 3.5A)
1.47A 6dchA-5n4lA:
undetectable
6dchA-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_0
(HIV-1 PROTEASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 12 ALA A 102
VAL A  88
ILE A  78
GLY A 175
ILE A 174
None
0.99A 6dilA-5n4lA:
undetectable
6dilA-5n4lA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ1_B_AB1B201_1
(HIV-1 PROTEASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 12 ALA A 102
VAL A  88
ILE A  78
GLY A 175
ILE A 174
None
0.84A 6dj1B-5n4lA:
undetectable
6dj1B-5n4lA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJ2_B_AB1B201_1
(HIV-1 PROTEASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 12 ALA A 102
VAL A  88
ILE A  78
GLY A 175
ILE A 174
None
0.85A 6dj2B-5n4lA:
undetectable
6dj2B-5n4lA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_B_GLYB709_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 GLY A  40
ASP A  42
ARG A  38
ARG A  43
None
1.22A 6dwdB-5n4lA:
undetectable
6dwdD-5n4lA:
undetectable
6dwdB-5n4lA:
undetectable
6dwdD-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWJ_B_GLYB710_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
4 / 5 ARG A  38
ARG A  43
GLY A  40
ASP A  42
None
1.16A 6dwjB-5n4lA:
undetectable
6dwjD-5n4lA:
undetectable
6dwjB-5n4lA:
undetectable
6dwjD-5n4lA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_3
(-)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 ASP A 569
ASP A 561
ASN A 320
None
0.85A 6gngB-5n4lA:
undetectable
6gngB-5n4lA:
8.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_0
(ADENOSINE DEAMINASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 12 HIS A1014
ILE A1021
ALA A 165
HIS A 162
HIS A 101
CU  A1101 (-3.2A)
None
None
CU  A1101 (-3.3A)
CU  A1105 (-3.1A)
1.16A 6n91A-5n4lA:
undetectable
6n91A-5n4lA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_0
(ADENOSINE DEAMINASE)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
5 / 12 HIS A1014
ILE A1021
ALA A 165
HIS A 162
HIS A 101
CU  A1101 (-3.2A)
None
None
CU  A1101 (-3.3A)
CU  A1105 (-3.1A)
1.17A 6n91B-5n4lA:
undetectable
6n91B-5n4lA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
5n4l CERULOPLASMIN
(Rattus
norvegicus)
3 / 3 ARG A 860
PHE A 635
PHE A 373
None
1.06A 6nknC-5n4lA:
undetectable
6nknJ-5n4lA:
undetectable
6nknC-5n4lA:
undetectable
6nknJ-5n4lA:
undetectable