SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5n56'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_B_ESTB1600_1
(ESTROGEN RECEPTOR)		 5n56 SUPEROXIDE DISMUTASE
[MN/FE] 1
(Staphylococcus
aureus) 		5 / 12 LEU A  83
LEU A 150
ILE A  53
GLY A  75
HIS A  78
 None
 0.89A 1g50B-5n56A:
undetectable		 1g50B-5n56A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_C_ESTC2600_1
(ESTROGEN RECEPTOR)		 5n56 SUPEROXIDE DISMUTASE
[MN/FE] 1
(Staphylococcus
aureus) 		5 / 11 LEU A  83
LEU A 150
ILE A  53
GLY A  75
HIS A  78
 None
 0.90A 1g50C-5n56A:
undetectable		 1g50C-5n56A:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_A_TESA903_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 5n56 SUPEROXIDE DISMUTASE
[MN/FE] 1
(Staphylococcus
aureus) 		4 / 6 VAL A  99
ILE A 102
TRP A 183
LEU A 160
 None
 1.05A 1j96A-5n56A:
undetectable		 1j96A-5n56A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 5n56 SUPEROXIDE DISMUTASE
[MN/FE] 1
(Staphylococcus
aureus) 		4 / 7 HIS A  27
ASP A  13
TYR A  10
HIS A  31
 MN  A 201 (-3.5A)
None
None
None
 1.49A 1v54N-5n56A:
undetectable
1v54P-5n56A:
undetectable		 1v54N-5n56A:
undetectable
1v54P-5n56A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		 5n56 SUPEROXIDE DISMUTASE
[MN/FE] 1
(Staphylococcus
aureus) 		5 / 12 SER A 126
GLN A 146
LEU A  88
HIS A  81
ALA A 166
 None
MN  A 201 ( 4.9A)
None
MN  A 201 (-3.3A)
None
 1.06A 2bxcA-5n56A:
undetectable		 2bxcA-5n56A:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5n56 SUPEROXIDE DISMUTASE
[MN/FE] 1
(Staphylococcus
aureus) 		4 / 7 HIS A  27
ASP A  13
TYR A  10
HIS A  31
 MN  A 201 (-3.5A)
None
None
None
 1.50A 2dyrA-5n56A:
1.7
2dyrC-5n56A:
undetectable		 2dyrA-5n56A:
undetectable
2dyrC-5n56A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5n56 SUPEROXIDE DISMUTASE
[MN/FE] 1
(Staphylococcus
aureus) 		4 / 7 HIS A  27
ASP A  13
TYR A  10
HIS A  31
 MN  A 201 (-3.5A)
None
None
None
 1.50A 2dyrN-5n56A:
undetectable
2dyrP-5n56A:
undetectable		 2dyrN-5n56A:
undetectable
2dyrP-5n56A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5n56 SUPEROXIDE DISMUTASE
[MN/FE] 1
(Staphylococcus
aureus) 		4 / 6 HIS A  27
ASP A  13
TYR A  10
HIS A  31
 MN  A 201 (-3.5A)
None
None
None
 1.49A 2dysA-5n56A:
1.5
2dysC-5n56A:
undetectable		 2dysA-5n56A:
undetectable
2dysC-5n56A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5n56 SUPEROXIDE DISMUTASE
[MN/FE] 1
(Staphylococcus
aureus) 		4 / 6 HIS A  27
ASP A  13
TYR A  10
HIS A  31
 MN  A 201 (-3.5A)
None
None
None
 1.47A 2dysN-5n56A:
undetectable
2dysP-5n56A:
undetectable		 2dysN-5n56A:
undetectable
2dysP-5n56A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5n56 SUPEROXIDE DISMUTASE
[MN/FE] 1
(Staphylococcus
aureus) 		4 / 7 HIS A  27
ASP A  13
TYR A  10
HIS A  31
 MN  A 201 (-3.5A)
None
None
None
 1.49A 2eijA-5n56A:
undetectable
2eijC-5n56A:
undetectable		 2eijA-5n56A:
undetectable
2eijC-5n56A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5n56 SUPEROXIDE DISMUTASE
[MN/FE] 1
(Staphylococcus
aureus) 		4 / 7 HIS A  27
ASP A  13
TYR A  10
HIS A  31
 MN  A 201 (-3.5A)
None
None
None
 1.50A 2eikA-5n56A:
undetectable
2eikC-5n56A:
undetectable		 2eikA-5n56A:
undetectable
2eikC-5n56A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5n56 SUPEROXIDE DISMUTASE
[MN/FE] 1
(Staphylococcus
aureus) 		4 / 7 HIS A  27
ASP A  13
TYR A  10
HIS A  31
 MN  A 201 (-3.5A)
None
None
None
 1.50A 2eikN-5n56A:
1.4
2eikP-5n56A:
undetectable		 2eikN-5n56A:
undetectable
2eikP-5n56A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5n56 SUPEROXIDE DISMUTASE
[MN/FE] 1
(Staphylococcus
aureus) 		4 / 6 HIS A  27
ASP A  13
TYR A  10
HIS A  31
 MN  A 201 (-3.5A)
None
None
None
 1.46A 2eimA-5n56A:
undetectable
2eimC-5n56A:
undetectable		 2eimA-5n56A:
undetectable
2eimC-5n56A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5n56 SUPEROXIDE DISMUTASE
[MN/FE] 1
(Staphylococcus
aureus) 		4 / 6 HIS A  27
ASP A  13
TYR A  10
HIS A  31
 MN  A 201 (-3.5A)
None
None
None
 1.49A 2einA-5n56A:
undetectable
2einC-5n56A:
undetectable		 2einA-5n56A:
undetectable
2einC-5n56A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_D_QPSD1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 5n56 SUPEROXIDE DISMUTASE
[MN/FE] 1
(Staphylococcus
aureus) 		5 / 10 THR A 143
VAL A 141
PHE A 116
VAL A 162
GLY A 127
 None
 1.43A 2x2iD-5n56A:
undetectable		 2x2iD-5n56A:
6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5n56 SUPEROXIDE DISMUTASE
[MN/FE] 1
(Staphylococcus
aureus) 		4 / 6 HIS A  27
ASP A  13
TYR A  10
HIS A  31
 MN  A 201 (-3.5A)
None
None
None
 1.50A 2zxwA-5n56A:
undetectable
2zxwC-5n56A:
undetectable		 2zxwA-5n56A:
undetectable
2zxwC-5n56A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5n56 SUPEROXIDE DISMUTASE
[MN/FE] 1
(Staphylococcus
aureus) 		4 / 6 HIS A  27
ASP A  13
TYR A  10
HIS A  31
 MN  A 201 (-3.5A)
None
None
None
 1.49A 2zxwN-5n56A:
undetectable
2zxwP-5n56A:
undetectable		 2zxwN-5n56A:
undetectable
2zxwP-5n56A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5n56 SUPEROXIDE DISMUTASE
[MN/FE] 1
(Staphylococcus
aureus) 		4 / 7 HIS A  27
ASP A  13
TYR A  10
HIS A  31
 MN  A 201 (-3.5A)
None
None
None
 1.48A 3abkN-5n56A:
undetectable
3abkP-5n56A:
undetectable		 3abkN-5n56A:
undetectable
3abkP-5n56A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5n56 SUPEROXIDE DISMUTASE
[MN/FE] 1
(Staphylococcus
aureus) 		4 / 7 HIS A  27
ASP A  13
TYR A  10
HIS A  31
 MN  A 201 (-3.5A)
None
None
None
 1.50A 3ag3A-5n56A:
undetectable
3ag3C-5n56A:
undetectable		 3ag3A-5n56A:
undetectable
3ag3C-5n56A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5n56 SUPEROXIDE DISMUTASE
[MN/FE] 1
(Staphylococcus
aureus) 		4 / 7 HIS A  27
ASP A  13
TYR A  10
HIS A  31
 MN  A 201 (-3.5A)
None
None
None
 1.49A 3ag4A-5n56A:
undetectable
3ag4C-5n56A:
undetectable		 3ag4A-5n56A:
undetectable
3ag4C-5n56A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5n56 SUPEROXIDE DISMUTASE
[MN/FE] 1
(Staphylococcus
aureus) 		4 / 7 HIS A  27
ASP A  13
TYR A  10
HIS A  31
 MN  A 201 (-3.5A)
None
None
None
 1.50A 3ag4N-5n56A:
undetectable
3ag4P-5n56A:
undetectable		 3ag4N-5n56A:
undetectable
3ag4P-5n56A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q95_A_ESLA700_1
(ESTROGEN RECEPTOR)		 5n56 SUPEROXIDE DISMUTASE
[MN/FE] 1
(Staphylococcus
aureus) 		5 / 12 LEU A  83
LEU A 150
ILE A  53
GLY A  75
HIS A  78
 None
 1.11A 3q95A-5n56A:
undetectable		 3q95A-5n56A:
16.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SG9_B_KANB305_1
(APH(2'')-ID)		 5n56 SUPEROXIDE DISMUTASE
[MN/FE] 1
(Staphylococcus
aureus) 		4 / 8 ASN A  40
SER A  82
HIS A  32
GLU A  54
 None
 1.10A 3sg9B-5n56A:
undetectable		 3sg9B-5n56A:
13.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1W_A_STRA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 5n56 SUPEROXIDE DISMUTASE
[MN/FE] 1
(Staphylococcus
aureus) 		4 / 7 VAL A  99
ILE A 102
TRP A 183
LEU A 160
 None
 0.98A 4l1wA-5n56A:
undetectable		 4l1wA-5n56A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YJI_A_TYLA502_1
(ARYL ACYLAMIDASE)		 5n56 SUPEROXIDE DISMUTASE
[MN/FE] 1
(Staphylococcus
aureus) 		4 / 7 LEU A  83
GLY A  76
GLY A  75
ILE A  56
 None
 0.62A 4yjiA-5n56A:
undetectable		 4yjiA-5n56A:
11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5n56 SUPEROXIDE DISMUTASE
[MN/FE] 1
(Staphylococcus
aureus) 		4 / 7 HIS A  27
ASP A  13
TYR A  10
HIS A  31
 MN  A 201 (-3.5A)
None
None
None
 1.49A 5b1bN-5n56A:
undetectable
5b1bP-5n56A:
undetectable		 5b1bN-5n56A:
undetectable
5b1bP-5n56A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_1
(WTFP-TAG,GP41)		 5n56 SUPEROXIDE DISMUTASE
[MN/FE] 1
(Staphylococcus
aureus) 		5 / 12 ALA A 181
LYS A 114
GLU A 110
GLU A 111
LEU A 109
 None
 1.26A 5nwuA-5n56A:
undetectable		 5nwuA-5n56A:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5n56 SUPEROXIDE DISMUTASE
[MN/FE] 1
(Staphylococcus
aureus) 		4 / 6 HIS A  27
ASP A  13
TYR A  10
HIS A  31
 MN  A 201 (-3.5A)
None
None
None
 1.50A 5x19N-5n56A:
undetectable
5x19P-5n56A:
undetectable		 5x19N-5n56A:
undetectable
5x19P-5n56A:
undetectable