SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5n57'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_B_CHDB500_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 5n57 SUPEROXIDE DISMUTASE
(Staphylococcus
aureus) 		4 / 4 LEU A  88
VAL A 186
ILE A  87
TRP A  85
 None
 1.40A 1s9qB-5n57A:
undetectable		 1s9qB-5n57A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 5n57 SUPEROXIDE DISMUTASE
(Staphylococcus
aureus) 		4 / 7 HIS A  27
ASP A  13
TYR A  10
HIS A  31
 MN  A 201 (-3.5A)
None
None
None
 1.48A 1v54A-5n57A:
1.6
1v54C-5n57A:
undetectable		 1v54A-5n57A:
undetectable
1v54C-5n57A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 5n57 SUPEROXIDE DISMUTASE
(Staphylococcus
aureus) 		4 / 7 HIS A  27
ASP A  13
TYR A  10
HIS A  31
 MN  A 201 (-3.5A)
None
None
None
 1.49A 1v55A-5n57A:
undetectable
1v55C-5n57A:
undetectable		 1v55A-5n57A:
undetectable
1v55C-5n57A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_1
(CES1 PROTEIN)		 5n57 SUPEROXIDE DISMUTASE
(Staphylococcus
aureus) 		5 / 12 GLY A  76
GLY A  75
VAL A  43
SER A  52
LEU A  48
 None
 1.15A 1ya4B-5n57A:
undetectable		 1ya4B-5n57A:
9.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		 5n57 SUPEROXIDE DISMUTASE
(Staphylococcus
aureus) 		5 / 12 SER A 126
GLN A 146
LEU A  88
HIS A  81
ALA A 166
 None
None
None
MN  A 201 (-3.5A)
MN  A 201 ( 4.9A)
 1.07A 2bxcA-5n57A:
undetectable		 2bxcA-5n57A:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5n57 SUPEROXIDE DISMUTASE
(Staphylococcus
aureus) 		4 / 7 HIS A  27
ASP A  13
TYR A  10
HIS A  31
 MN  A 201 (-3.5A)
None
None
None
 1.48A 2dyrA-5n57A:
undetectable
2dyrC-5n57A:
undetectable		 2dyrA-5n57A:
undetectable
2dyrC-5n57A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5n57 SUPEROXIDE DISMUTASE
(Staphylococcus
aureus) 		4 / 6 HIS A  27
ASP A  13
TYR A  10
HIS A  31
 MN  A 201 (-3.5A)
None
None
None
 1.48A 2dysA-5n57A:
undetectable
2dysC-5n57A:
undetectable		 2dysA-5n57A:
undetectable
2dysC-5n57A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5n57 SUPEROXIDE DISMUTASE
(Staphylococcus
aureus) 		4 / 6 HIS A  27
ASP A  13
TYR A  10
HIS A  31
 MN  A 201 (-3.5A)
None
None
None
 1.46A 2dysN-5n57A:
1.6
2dysP-5n57A:
undetectable		 2dysN-5n57A:
undetectable
2dysP-5n57A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5n57 SUPEROXIDE DISMUTASE
(Staphylococcus
aureus) 		4 / 7 HIS A  27
ASP A  13
TYR A  10
HIS A  31
 MN  A 201 (-3.5A)
None
None
None
 1.48A 2eijA-5n57A:
undetectable
2eijC-5n57A:
undetectable		 2eijA-5n57A:
undetectable
2eijC-5n57A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5n57 SUPEROXIDE DISMUTASE
(Staphylococcus
aureus) 		4 / 7 HIS A  27
ASP A  13
TYR A  10
HIS A  31
 MN  A 201 (-3.5A)
None
None
None
 1.49A 2eijN-5n57A:
1.4
2eijP-5n57A:
undetectable		 2eijN-5n57A:
undetectable
2eijP-5n57A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5n57 SUPEROXIDE DISMUTASE
(Staphylococcus
aureus) 		4 / 6 HIS A  27
ASP A  13
TYR A  10
HIS A  31
 MN  A 201 (-3.5A)
None
None
None
 1.48A 2einA-5n57A:
undetectable
2einC-5n57A:
undetectable		 2einA-5n57A:
undetectable
2einC-5n57A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5n57 SUPEROXIDE DISMUTASE
(Staphylococcus
aureus) 		4 / 6 HIS A  27
ASP A  13
TYR A  10
HIS A  31
 MN  A 201 (-3.5A)
None
None
None
 1.48A 2zxwA-5n57A:
undetectable
2zxwC-5n57A:
undetectable		 2zxwA-5n57A:
undetectable
2zxwC-5n57A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5n57 SUPEROXIDE DISMUTASE
(Staphylococcus
aureus) 		4 / 6 HIS A  27
ASP A  13
TYR A  10
HIS A  31
 MN  A 201 (-3.5A)
None
None
None
 1.48A 2zxwN-5n57A:
undetectable
2zxwP-5n57A:
undetectable		 2zxwN-5n57A:
undetectable
2zxwP-5n57A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5n57 SUPEROXIDE DISMUTASE
(Staphylococcus
aureus) 		4 / 7 HIS A  27
ASP A  13
TYR A  10
HIS A  31
 MN  A 201 (-3.5A)
None
None
None
 1.48A 3abmN-5n57A:
undetectable
3abmP-5n57A:
undetectable		 3abmN-5n57A:
undetectable
3abmP-5n57A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5n57 SUPEROXIDE DISMUTASE
(Staphylococcus
aureus) 		4 / 7 HIS A  27
ASP A  13
TYR A  10
HIS A  31
 MN  A 201 (-3.5A)
None
None
None
 1.49A 3ag2N-5n57A:
undetectable
3ag2P-5n57A:
undetectable		 3ag2N-5n57A:
undetectable
3ag2P-5n57A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5n57 SUPEROXIDE DISMUTASE
(Staphylococcus
aureus) 		4 / 7 HIS A  27
ASP A  13
TYR A  10
HIS A  31
 MN  A 201 (-3.5A)
None
None
None
 1.48A 3ag3A-5n57A:
undetectable
3ag3C-5n57A:
undetectable		 3ag3A-5n57A:
undetectable
3ag3C-5n57A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5n57 SUPEROXIDE DISMUTASE
(Staphylococcus
aureus) 		4 / 7 HIS A  27
ASP A  13
TYR A  10
HIS A  31
 MN  A 201 (-3.5A)
None
None
None
 1.48A 3ag3N-5n57A:
undetectable
3ag3P-5n57A:
undetectable		 3ag3N-5n57A:
undetectable
3ag3P-5n57A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5n57 SUPEROXIDE DISMUTASE
(Staphylococcus
aureus) 		4 / 7 HIS A  27
ASP A  13
TYR A  10
HIS A  31
 MN  A 201 (-3.5A)
None
None
None
 1.48A 3ag4A-5n57A:
undetectable
3ag4C-5n57A:
undetectable		 3ag4A-5n57A:
undetectable
3ag4C-5n57A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CO4_A_GCSA401_1
(CHITINASE)		 5n57 SUPEROXIDE DISMUTASE
(Staphylococcus
aureus) 		3 / 3 GLU A  86
HIS A  81
HIS A  78
 None
MN  A 201 (-3.5A)
None
 0.85A 3co4A-5n57A:
undetectable		 3co4A-5n57A:
12.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OI8_A_ADNA2_1
(UNCHARACTERIZED
PROTEIN)		 5n57 SUPEROXIDE DISMUTASE
(Staphylococcus
aureus) 		4 / 6 ILE A  57
ASN A  80
PRO A 156
LEU A 150
 None
 1.24A 3oi8A-5n57A:
undetectable		 3oi8A-5n57A:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_A_RBFA190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 5n57 SUPEROXIDE DISMUTASE
(Staphylococcus
aureus) 		5 / 12 LEU A 150
THR A 151
GLY A  76
LEU A 159
LEU A  53
 None
 1.18A 3p5nA-5n57A:
undetectable		 3p5nA-5n57A:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDT_A_ACTA407_0
(FAD:PROTEIN FMN
TRANSFERASE)		 5n57 SUPEROXIDE DISMUTASE
(Staphylococcus
aureus) 		3 / 3 ASP A 100
GLY A  96
ASP A 192
 None
 0.59A 4xdtA-5n57A:
undetectable		 4xdtA-5n57A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC1_B_486B801_2
(GLUCOCORTICOID
RECEPTOR)		 5n57 SUPEROXIDE DISMUTASE
(Staphylococcus
aureus) 		5 / 12 ASN A  73
LEU A  39
GLY A  75
GLY A  76
LEU A  48
 None
 1.16A 5uc1B-5n57A:
undetectable		 5uc1B-5n57A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5n57 SUPEROXIDE DISMUTASE
(Staphylococcus
aureus) 		4 / 6 HIS A  27
ASP A  13
TYR A  10
HIS A  31
 MN  A 201 (-3.5A)
None
None
None
 1.49A 6nknA-5n57A:
undetectable
6nknC-5n57A:
undetectable		 6nknA-5n57A:
undetectable
6nknC-5n57A:
undetectable