SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5n5p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z11_D_8MOD501_0
(CYTOCHROME P450,
FAMILY 2, SUBFAMILY
A, POLYPEPTIDE 6)		 5n5p PUTATIVE
CELLULOSOMAL
SCAFFOLDIN PROTEIN
PUTATIVE
CELLULOSOMAL
SCAFFOLDIN PROTEIN
(Ruminococcus
flavefaciens;
Ruminococcus
flavefaciens) 		5 / 10 PHE A 812
VAL B 666
ILE A 820
GLY A 819
ILE A 861
 None
 1.07A 1z11D-5n5pA:
undetectable		 1z11D-5n5pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGP_A_PCFA1213_0
(WNT INHIBITORY
FACTOR 1)		 5n5p PUTATIVE
CELLULOSOMAL
SCAFFOLDIN PROTEIN
PUTATIVE
CELLULOSOMAL
SCAFFOLDIN PROTEIN
(Ruminococcus
flavefaciens;
Ruminococcus
flavefaciens) 		5 / 12 ILE A 865
LEU A 867
ILE A 861
VAL B 662
VAL B 666
 None
 0.96A 2ygpA-5n5pA:
undetectable		 2ygpA-5n5pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B7P_C_SPMC503_1
(SPERMIDINE SYNTHASE)		 5n5p PUTATIVE
CELLULOSOMAL
SCAFFOLDIN PROTEIN
(Ruminococcus
flavefaciens) 		5 / 12 GLN A 808
SER A 794
TYR A 810
PRO A 803
ILE A 829
 None
 1.19A 3b7pC-5n5pA:
undetectable		 3b7pC-5n5pA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUR_B_TESB340_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 5n5p PUTATIVE
CELLULOSOMAL
SCAFFOLDIN PROTEIN
(Ruminococcus
flavefaciens) 		5 / 10 ILE A 828
TRP A 748
TYR A 798
VAL B 665
VAL B 662
 None
 1.42A 3burB-5n5pA:
undetectable		 3burB-5n5pA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OF4_B_ACTB313_0
(NITROREDUCTASE)		 5n5p PUTATIVE
CELLULOSOMAL
SCAFFOLDIN PROTEIN
(Ruminococcus
flavefaciens) 		3 / 3 ALA B 646
VAL B 701
GLN B 694
 None
 0.75A 3of4B-5n5pB:
undetectable		 3of4B-5n5pB:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJ8_A_SUVA2001_2
(HUMAN OX1R FUSION
PROTEIN TO P.ABYSII
GLYCOGEN SYNTHASE)		 5n5p PUTATIVE
CELLULOSOMAL
SCAFFOLDIN PROTEIN
(Ruminococcus
flavefaciens) 		4 / 6 TRP A 748
ILE A 853
ILE B 717
VAL B 720
 None
 0.94A 4zj8A-5n5pA:
undetectable		 4zj8A-5n5pA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGK_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5n5p PUTATIVE
CELLULOSOMAL
SCAFFOLDIN PROTEIN
(Ruminococcus
flavefaciens) 		3 / 3 VAL A 835
TYR A 844
GLN A 783
 None
 0.67A 5qgkA-5n5pA:
undetectable		 5qgkA-5n5pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGR_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5n5p PUTATIVE
CELLULOSOMAL
SCAFFOLDIN PROTEIN
(Ruminococcus
flavefaciens) 		3 / 3 VAL A 835
TYR A 844
GLN A 783
 None
 0.69A 5qgrA-5n5pA:
undetectable		 5qgrA-5n5pA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGT_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 5n5p PUTATIVE
CELLULOSOMAL
SCAFFOLDIN PROTEIN
(Ruminococcus
flavefaciens) 		3 / 3 VAL A 835
TYR A 844
GLN A 783
 None
 0.68A 5qgtA-5n5pA:
undetectable		 5qgtA-5n5pA:
undetectable