SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5n6r'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)
5n6r BREAKPOINT CLUSTER
REGION PROTEIN

(Homo
sapiens)
5 / 12 PRO A 523
LEU A 527
VAL A 537
GLN A 614
SER A 619
None
1.19A 4a84A-5n6rA:
undetectable
4a84A-5n6rA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AGA_A_ACTA1131_0
(LYSOZYME C)
5n6r BREAKPOINT CLUSTER
REGION PROTEIN

(Homo
sapiens)
3 / 3 ASN A 637
ASP A 629
ASN A 627
None
0.70A 4agaA-5n6rA:
undetectable
4agaA-5n6rA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3R_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)
5n6r BREAKPOINT CLUSTER
REGION PROTEIN

(Homo
sapiens)
3 / 3 ASP A 670
ARG A 567
THR A 664
None
0.90A 4p3rA-5n6rA:
undetectable
4p3rA-5n6rA:
undetectable