SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5n6v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_2
(ADENOSINE DEAMINASE)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		4 / 5 LEU A 615
LEU A 617
SER A 473
LEU A 470
 None
 0.88A 1a4lC-5n6vA:
2.3		 1a4lC-5n6vA:
13.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BZF_A_TMQA170_1
(DIHYDROFOLATE
REDUCTASE)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		5 / 12 ALA A 319
LEU A 273
PHE A 265
LEU A  47
ALA A 314
 None
 1.10A 1bzfA-5n6vA:
undetectable		 1bzfA-5n6vA:
16.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_A_QPSA1001_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		6 / 12 TYR A 147
ASP A 286
ALA A 287
HIS A 392
ASP A 393
ARG A 513
 TRS  A 701 (-3.5A)
TRS  A 701 (-2.8A)
TRS  A 701 ( 4.0A)
None
TRS  A 701 ( 4.6A)
None
 0.71A 1dedA-5n6vA:
25.1		 1dedA-5n6vA:
8.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DED_B_QPSB1501_1
(CYCLODEXTRIN
GLUCANOTRANSFERASE)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		8 / 12 TYR A 147
ARG A 284
ASP A 286
ALA A 287
GLU A 328
HIS A 392
ASP A 393
ARG A 513
 TRS  A 701 (-3.5A)
TRS  A 701 ( 4.6A)
TRS  A 701 (-2.8A)
TRS  A 701 ( 4.0A)
TRS  A 701 (-2.8A)
None
TRS  A 701 ( 4.6A)
None
 0.84A 1dedB-5n6vA:
23.3		 1dedB-5n6vA:
8.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		5 / 12 ILE A 468
LEU A 361
ALA A 475
ILE A 474
ILE A 567
 None
 0.96A 1epbA-5n6vA:
undetectable		 1epbA-5n6vA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		5 / 12 ILE A 468
LEU A 361
ALA A 475
ILE A 474
ILE A 567
 None
 0.95A 1epbB-5n6vA:
undetectable		 1epbB-5n6vA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FK9_A_EFZA999_1
(HIV-1 RT, A-CHAIN)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		5 / 10 LEU A 471
VAL A 622
TYR A 620
GLY A 579
LEU A 361
 None
 1.14A 1fk9A-5n6vA:
undetectable		 1fk9A-5n6vA:
8.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZ4_A_BEZA784_0
(MALT REGULATORY
PROTEIN)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		4 / 6 LEU A 356
LEU A 352
PRO A 351
MET A 354
 None
 1.34A 1hz4A-5n6vA:
undetectable		 1hz4A-5n6vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_1
(ALPHA-AMYLASE)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		5 / 12 HIS A 187
ALA A 287
GLU A 328
ILE A 330
ASP A 393
 TRS  A 701 (-3.9A)
TRS  A 701 ( 4.0A)
TRS  A 701 (-2.8A)
None
TRS  A 701 ( 4.6A)
 0.78A 1kxhA-5n6vA:
19.1		 1kxhA-5n6vA:
10.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LW0_A_NVPA999_1
(HIV-1 REVERSE
TRANSCRIPTASE)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		5 / 10 LEU A 471
VAL A 622
TYR A 620
GLY A 579
LEU A 361
 None
 1.14A 1lw0A-5n6vA:
undetectable		 1lw0A-5n6vA:
8.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_A_THAA1_1
(LIVER
CARBOXYLESTERASE I)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		5 / 11 LEU A 130
PHE A 122
GLY A 101
LEU A 132
MET A 133
 None
 1.08A 1mx1A-5n6vA:
undetectable		 1mx1A-5n6vA:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		7 / 12 TYR A 147
HIS A 187
ARG A 284
ASP A 286
GLU A 328
HIS A 392
ASP A 393
 TRS  A 701 (-3.5A)
TRS  A 701 (-3.9A)
TRS  A 701 ( 4.6A)
TRS  A 701 (-2.8A)
TRS  A 701 (-2.8A)
None
TRS  A 701 ( 4.6A)
 0.46A 1mxdA-5n6vA:
20.7		 1mxdA-5n6vA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA735_1
(ALPHA AMYLASE)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		7 / 12 TYR A 147
HIS A 187
PHE A 250
ARG A 284
ASP A 286
HIS A 392
ASP A 393
 TRS  A 701 (-3.5A)
TRS  A 701 (-3.9A)
TRS  A 701 (-3.9A)
TRS  A 701 ( 4.6A)
TRS  A 701 (-2.8A)
None
TRS  A 701 ( 4.6A)
 1.08A 1mxdA-5n6vA:
20.7		 1mxdA-5n6vA:
11.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		3 / 3 GLU A 271
TRP A 194
LYS A 113
 None
1PE  A 709 ( 4.4A)
None
 1.33A 1qu2A-5n6vA:
undetectable		 1qu2A-5n6vA:
6.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		4 / 7 ALA A 329
PHE A 185
ASN A 301
GLU A 344
 None
 0.99A 1t9wA-5n6vA:
undetectable		 1t9wA-5n6vA:
5.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_A_NFZA1219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		4 / 8 PHE A 417
GLY A 411
THR A 398
PHE A 399
 GLC  A 704 ( 4.0A)
None
None
None
 1.08A 1ykiA-5n6vA:
undetectable
1ykiB-5n6vA:
undetectable		 1ykiA-5n6vA:
14.88
1ykiB-5n6vA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_C_NFZC3219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		4 / 8 PHE A 417
GLY A 411
THR A 398
PHE A 399
 GLC  A 704 ( 4.0A)
None
None
None
 1.07A 1ykiC-5n6vA:
undetectable
1ykiD-5n6vA:
undetectable		 1ykiC-5n6vA:
14.88
1ykiD-5n6vA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_D_NFZD4219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		4 / 8 THR A 398
PHE A 399
PHE A 417
GLY A 411
 None
None
GLC  A 704 ( 4.0A)
None
 1.09A 1ykiC-5n6vA:
undetectable
1ykiD-5n6vA:
undetectable		 1ykiC-5n6vA:
14.88
1ykiD-5n6vA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		5 / 11 LEU A   7
LEU A  61
LEU A  43
LYS A  42
LEU A  65
 None
 1.12A 2ceoA-5n6vA:
undetectable		 2ceoA-5n6vA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E5D_A_NCAA1501_0
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		4 / 7 ALA A 319
ARG A  35
ASP A  28
TYR A  72
 None
 1.20A 2e5dA-5n6vA:
2.1
2e5dB-5n6vA:
undetectable		 2e5dA-5n6vA:
undetectable
2e5dB-5n6vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HND_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		5 / 10 LEU A 471
VAL A 622
TYR A 620
GLY A 579
LEU A 361
 None
 1.18A 2hndA-5n6vA:
undetectable		 2hndA-5n6vA:
9.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HNY_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		5 / 10 LEU A 471
VAL A 622
TYR A 620
GLY A 579
LEU A 361
 None
 1.20A 2hnyA-5n6vA:
undetectable		 2hnyA-5n6vA:
8.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_1
(SAM DEPENDENT
METHYLTRANSFERASE)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		4 / 4 ASP A 506
ASP A 501
ASP A 144
GLY A 141
 None
None
TRS  A 701 (-2.8A)
None
 1.33A 2igtC-5n6vA:
undetectable		 2igtC-5n6vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		4 / 8 PHE A 422
GLY A 396
MET A 354
ILE A 330
 None
 0.96A 2qwxA-5n6vA:
undetectable
2qwxB-5n6vA:
undetectable		 2qwxA-5n6vA:
17.27
2qwxB-5n6vA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RIW_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		5 / 10 LEU A   7
LEU A  61
LEU A  43
LYS A  42
LEU A  65
 None
 1.08A 2riwA-5n6vA:
undetectable
2riwB-5n6vA:
undetectable		 2riwA-5n6vA:
12.99
2riwB-5n6vA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1500_1
(CYTOCHROME P450 3A4)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		5 / 11 PHE A 312
ARG A  75
ILE A 169
ALA A 179
LEU A 283
 None
 1.26A 2v0mA-5n6vA:
undetectable		 2v0mA-5n6vA:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1500_1
(CYTOCHROME P450 3A4)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		5 / 11 PHE A 312
LEU A 135
ILE A 169
ALA A 179
LEU A 283
 None
 1.23A 2v0mA-5n6vA:
undetectable		 2v0mA-5n6vA:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_B_KLNB1498_1
(CYTOCHROME P450 3A4)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		5 / 9 PHE A 312
LEU A 135
ILE A 169
ALA A 179
LEU A 283
 None
 1.14A 2v0mB-5n6vA:
undetectable		 2v0mB-5n6vA:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1498_1
(CYTOCHROME P450 3A4)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		5 / 12 PHE A 312
LEU A 135
PHE A 136
ILE A 169
ALA A 179
 None
 1.26A 2v0mC-5n6vA:
undetectable		 2v0mC-5n6vA:
10.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN6_A_T44A1370_1
(THYROXINE-BINDING
GLOBULIN)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		5 / 10 LEU A   7
LEU A  61
LEU A  43
LYS A  42
LEU A  65
 None
 1.01A 2xn6A-5n6vA:
undetectable
2xn6B-5n6vA:
undetectable		 2xn6A-5n6vA:
14.33
2xn6B-5n6vA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIF_A_SAMA298_0
(PUTATIVE
MODIFICATION
METHYLASE)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		5 / 12 PRO A 514
GLY A 487
THR A 492
THR A 450
GLU A 489
 None
 1.13A 2zifA-5n6vA:
undetectable		 2zifA-5n6vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_A_ACRA5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		7 / 12 ARG A 284
ASP A 286
ALA A 287
GLU A 328
HIS A 392
ASP A 393
ASP A 144
 TRS  A 701 ( 4.6A)
TRS  A 701 (-2.8A)
TRS  A 701 ( 4.0A)
TRS  A 701 (-2.8A)
None
TRS  A 701 ( 4.6A)
TRS  A 701 (-2.8A)
 0.70A 3aicA-5n6vA:
6.2		 3aicA-5n6vA:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		7 / 12 ARG A 284
ASP A 286
ALA A 287
GLU A 328
HIS A 392
ASP A 393
ASP A 144
 TRS  A 701 ( 4.6A)
TRS  A 701 (-2.8A)
TRS  A 701 ( 4.0A)
TRS  A 701 (-2.8A)
None
TRS  A 701 ( 4.6A)
TRS  A 701 (-2.8A)
 0.70A 3aicB-5n6vA:
4.4		 3aicB-5n6vA:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_B_ACRB5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		6 / 12 ARG A 284
ASP A 286
GLU A 328
HIS A 392
ASP A 393
GLN A 254
 TRS  A 701 ( 4.6A)
TRS  A 701 (-2.8A)
TRS  A 701 (-2.8A)
None
TRS  A 701 ( 4.6A)
TRS  A 701 (-4.2A)
 0.96A 3aicB-5n6vA:
4.4		 3aicB-5n6vA:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		8 / 12 ARG A 284
ASP A 286
ALA A 287
GLU A 328
HIS A 392
ASP A 393
ASP A 144
TYR A 147
 TRS  A 701 ( 4.6A)
TRS  A 701 (-2.8A)
TRS  A 701 ( 4.0A)
TRS  A 701 (-2.8A)
None
TRS  A 701 ( 4.6A)
TRS  A 701 (-2.8A)
TRS  A 701 (-3.5A)
 0.67A 3aicC-5n6vA:
6.3		 3aicC-5n6vA:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_C_ACRC5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		6 / 12 ARG A 284
GLU A 328
HIS A 392
ASP A 393
TYR A 147
GLN A 254
 TRS  A 701 ( 4.6A)
TRS  A 701 (-2.8A)
None
TRS  A 701 ( 4.6A)
TRS  A 701 (-3.5A)
TRS  A 701 (-4.2A)
 1.03A 3aicC-5n6vA:
6.3		 3aicC-5n6vA:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_D_ACRD5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		7 / 12 ARG A 284
ASP A 286
ALA A 287
GLU A 328
HIS A 392
ASP A 393
ASP A 144
 TRS  A 701 ( 4.6A)
TRS  A 701 (-2.8A)
TRS  A 701 ( 4.0A)
TRS  A 701 (-2.8A)
None
TRS  A 701 ( 4.6A)
TRS  A 701 (-2.8A)
 0.73A 3aicD-5n6vA:
6.3		 3aicD-5n6vA:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_E_ACRE5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		7 / 12 ARG A 284
ASP A 286
ALA A 287
GLU A 328
HIS A 392
ASP A 393
ASP A 144
 TRS  A 701 ( 4.6A)
TRS  A 701 (-2.8A)
TRS  A 701 ( 4.0A)
TRS  A 701 (-2.8A)
None
TRS  A 701 ( 4.6A)
TRS  A 701 (-2.8A)
 0.72A 3aicE-5n6vA:
6.2		 3aicE-5n6vA:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		7 / 12 ARG A 284
ASP A 286
ALA A 287
GLU A 328
HIS A 392
ASP A 393
ASP A 144
 TRS  A 701 ( 4.6A)
TRS  A 701 (-2.8A)
TRS  A 701 ( 4.0A)
TRS  A 701 (-2.8A)
None
TRS  A 701 ( 4.6A)
TRS  A 701 (-2.8A)
 0.70A 3aicF-5n6vA:
6.2		 3aicF-5n6vA:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_F_ACRF5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		5 / 12 ARG A 284
GLU A 328
HIS A 392
ASP A 393
GLN A 254
 TRS  A 701 ( 4.6A)
TRS  A 701 (-2.8A)
None
TRS  A 701 ( 4.6A)
TRS  A 701 (-4.2A)
 0.87A 3aicF-5n6vA:
6.2		 3aicF-5n6vA:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		7 / 12 ARG A 284
ASP A 286
ALA A 287
GLU A 328
HIS A 392
ASP A 393
ASP A 144
 TRS  A 701 ( 4.6A)
TRS  A 701 (-2.8A)
TRS  A 701 ( 4.0A)
TRS  A 701 (-2.8A)
None
TRS  A 701 ( 4.6A)
TRS  A 701 (-2.8A)
 0.68A 3aicG-5n6vA:
6.4		 3aicG-5n6vA:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_G_ACRG5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		6 / 12 ARG A 284
ASP A 286
GLU A 328
HIS A 392
ASP A 393
GLN A 254
 TRS  A 701 ( 4.6A)
TRS  A 701 (-2.8A)
TRS  A 701 (-2.8A)
None
TRS  A 701 ( 4.6A)
TRS  A 701 (-4.2A)
 0.97A 3aicG-5n6vA:
6.4		 3aicG-5n6vA:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		7 / 12 ARG A 284
ASP A 286
ALA A 287
GLU A 328
HIS A 392
ASP A 393
ASP A 144
 TRS  A 701 ( 4.6A)
TRS  A 701 (-2.8A)
TRS  A 701 ( 4.0A)
TRS  A 701 (-2.8A)
None
TRS  A 701 ( 4.6A)
TRS  A 701 (-2.8A)
 0.71A 3aicH-5n6vA:
6.5		 3aicH-5n6vA:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AIC_H_ACRH5044_1
(GLUCOSYLTRANSFERASE-
SI)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		5 / 12 ARG A 284
GLU A 328
HIS A 392
ASP A 393
GLN A 254
 TRS  A 701 ( 4.6A)
TRS  A 701 (-2.8A)
None
TRS  A 701 ( 4.6A)
TRS  A 701 (-4.2A)
 0.95A 3aicH-5n6vA:
6.5		 3aicH-5n6vA:
6.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_1
(O-METHYLTRANSFERASE)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		3 / 3 ASP A 507
PHE A 229
SER A 143
 None
 0.80A 3i5uB-5n6vA:
undetectable		 3i5uB-5n6vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP5_B_KANB2002_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		3 / 3 ALA A 287
ARG A 284
LYS A 326
 TRS  A 701 ( 4.0A)
TRS  A 701 ( 4.6A)
None
 1.09A 3kp5B-5n6vA:
undetectable		 3kp5B-5n6vA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LCV_B_SAMB301_1
(SISOMICIN-GENTAMICIN
RESISTANCE METHYLASE
SGM)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		3 / 3 ARG A 390
ASP A 507
GLN A 254
 None
None
TRS  A 701 (-4.2A)
 0.95A 3lcvB-5n6vA:
undetectable		 3lcvB-5n6vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_D_VIBD223_1
(THIAMINE
PYROPHOSPHOKINASE)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		4 / 8 ASP A 256
HIS A 306
LEU A 225
CYH A 299
 None
 0.91A 3lm8B-5n6vA:
undetectable
3lm8D-5n6vA:
3.2		 3lm8B-5n6vA:
15.69
3lm8D-5n6vA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP1_A_NVPA701_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		5 / 10 LEU A 471
VAL A 622
TYR A 620
GLY A 579
LEU A 361
 None
 1.15A 3lp1A-5n6vA:
undetectable		 3lp1A-5n6vA:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_B_08JB2_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		4 / 7 VAL A 181
LEU A 132
LEU A 135
ILE A 169
 None
 0.95A 3u5kB-5n6vA:
undetectable		 3u5kB-5n6vA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U8Q_A_NPUA7231_1
(LACTOTRANSFERRIN)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		4 / 5 THR A 478
GLY A 480
PRO A 482
ASN A 387
 None
 1.00A 3u8qA-5n6vA:
undetectable		 3u8qA-5n6vA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_F_ZPCF1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		5 / 12 GLU A  27
HIS A  39
TYR A  72
ILE A  11
GLU A  87
 None
 1.49A 4a97F-5n6vA:
0.0
4a97J-5n6vA:
0.0		 4a97F-5n6vA:
14.33
4a97J-5n6vA:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_B_TYLB1187_1
(BROMODOMAIN
CONTAINING 2)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		4 / 5 VAL A 181
LEU A 132
LEU A 135
ILE A 169
 None
 0.94A 4a9jB-5n6vA:
undetectable		 4a9jB-5n6vA:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR2_A_PARA1609_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S9
30S RIBOSOMAL
PROTEIN S10)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		3 / 3 TYR A 620
ARG A 364
SER A 582
 None
 0.94A 4dr2I-5n6vA:
undetectable
4dr2J-5n6vA:
undetectable		 4dr2I-5n6vA:
19.23
4dr2J-5n6vA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF7_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		3 / 3 TYR A 620
ARG A 364
SER A 582
 None
 0.94A 4lf7I-5n6vA:
undetectable
4lf7J-5n6vA:
undetectable		 4lf7I-5n6vA:
19.23
4lf7J-5n6vA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LF8_A_PARA1817_1
(16S RRNA
RIBOSOMAL PROTEIN S9
RIBOSOMAL PROTEIN
S10)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		3 / 3 TYR A 620
ARG A 364
SER A 582
 None
 0.94A 4lf8I-5n6vA:
undetectable
4lf8J-5n6vA:
undetectable		 4lf8I-5n6vA:
19.23
4lf8J-5n6vA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		5 / 12 ILE A  82
LEU A  79
VAL A 181
ALA A 179
SER A 178
 None
None
None
None
FRU  A 707 (-2.7A)
 0.96A 4m11C-5n6vA:
undetectable		 4m11C-5n6vA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_D_MXMD606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		5 / 12 ILE A  82
LEU A  79
VAL A 181
ALA A 179
SER A 178
 None
None
None
None
FRU  A 707 (-2.7A)
 0.96A 4m11D-5n6vA:
undetectable		 4m11D-5n6vA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_D_MXMD606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		5 / 12 ILE A 567
LEU A 369
VAL A 389
ALA A 475
SER A 473
 None
 1.31A 4m11D-5n6vA:
undetectable		 4m11D-5n6vA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_G_IPHG101_0
(INSULIN)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		5 / 11 LEU A 172
CYH A 103
HIS A 131
LEU A 130
ALA A 179
 None
 1.14A 4p65B-5n6vA:
undetectable
4p65D-5n6vA:
undetectable
4p65G-5n6vA:
undetectable
4p65H-5n6vA:
undetectable		 4p65B-5n6vA:
undetectable
4p65D-5n6vA:
undetectable
4p65G-5n6vA:
undetectable
4p65H-5n6vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6S_A_DAHA304_1
(TYROSINASE)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		4 / 5 ASN A 367
LEU A 368
GLU A 365
THR A 363
 None
None
None
GLC  A 704 ( 4.7A)
 1.43A 4p6sA-5n6vA:
undetectable		 4p6sA-5n6vA:
18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_A_ML1A302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		4 / 8 PHE A 422
GLY A 396
MET A 354
ILE A 330
 None
 0.97A 4qogA-5n6vA:
undetectable
4qogB-5n6vA:
undetectable		 4qogA-5n6vA:
17.27
4qogB-5n6vA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		4 / 8 SER A 143
ASP A 144
ARG A 513
GLN A 254
 None
TRS  A 701 (-2.8A)
None
TRS  A 701 (-4.2A)
 1.00A 4umjA-5n6vA:
undetectable		 4umjA-5n6vA:
15.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YV5_A_SVRA205_1
(BASIC PHOSPHOLIPASE
A2 HOMOLOG 2)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		4 / 7 LYS A  97
TYR A 129
LEU A 127
PHE A 122
 None
 1.21A 4yv5A-5n6vA:
undetectable		 4yv5A-5n6vA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSY_B_ACRB601_1
(4-ALPHA-GLUCANOTRANS
FERASE DPE1,
CHLOROPLASTIC/AMYLOP
LASTIC)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		5 / 12 ARG A 284
ASP A 286
GLU A 328
HIS A 392
ASP A 393
 TRS  A 701 ( 4.6A)
TRS  A 701 (-2.8A)
TRS  A 701 (-2.8A)
None
TRS  A 701 ( 4.6A)
 0.44A 5csyB-5n6vA:
14.9		 5csyB-5n6vA:
9.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_A_SAMA801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		5 / 12 ILE A 468
GLY A 491
THR A 492
ALA A 451
LEU A 471
 None
 1.24A 5hw4A-5n6vA:
undetectable		 5hw4A-5n6vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_C_SAMC801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		5 / 12 ILE A 468
GLY A 491
THR A 492
ALA A 451
LEU A 471
 None
 1.20A 5hw4C-5n6vA:
undetectable		 5hw4C-5n6vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_A_BEZA507_0
(BETA-LACTAMASE VIM-2)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		3 / 3 THR A 249
HIS A 233
ASN A 251
 None
 0.89A 5n4tA-5n6vA:
undetectable		 5n4tA-5n6vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMW_B_RBFB201_1
(GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		4 / 7 ARG A 524
TYR A 535
GLU A 124
LEU A 486
 None
 1.02A 5umwB-5n6vA:
undetectable
5umwE-5n6vA:
undetectable		 5umwB-5n6vA:
23.60
5umwE-5n6vA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		3 / 3 ASP A 182
ARG A 284
ASP A 144
 None
TRS  A 701 ( 4.6A)
TRS  A 701 (-2.8A)
 0.80A 5zvgA-5n6vA:
undetectable		 5zvgA-5n6vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		3 / 3 ASP A 182
ARG A 284
ASP A 144
 None
TRS  A 701 ( 4.6A)
TRS  A 701 (-2.8A)
 0.83A 5zvgB-5n6vA:
undetectable		 5zvgB-5n6vA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AG0_A_ACRA610_0
(ALPHA-AMYLASE)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		5 / 12 TYR A 147
HIS A 187
ASP A 286
HIS A 392
ASP A 393
 TRS  A 701 (-3.5A)
TRS  A 701 (-3.9A)
TRS  A 701 (-2.8A)
None
TRS  A 701 ( 4.6A)
 0.57A 6ag0A-5n6vA:
18.4		 6ag0A-5n6vA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		5 / 10 LEU A 471
VAL A 622
TYR A 620
GLY A 579
LEU A 361
 None
 1.08A 6bsiA-5n6vA:
undetectable		 6bsiA-5n6vA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSJ_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		5 / 10 LEU A 471
VAL A 622
TYR A 620
GLY A 579
LEU A 361
 None
 1.07A 6bsjA-5n6vA:
undetectable		 6bsjA-5n6vA:
13.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F6I_A_8PRA509_1
(ENVELOPE
GLYCOPROTEIN,GP,GP1
ENVELOPE
GLYCOPROTEIN)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		5 / 12 VAL A 105
LEU A 159
ALA A 109
GLY A 110
LEU A 130
 None
 1.16A 6f6iA-5n6vA:
undetectable
6f6iB-5n6vA:
undetectable		 6f6iA-5n6vA:
20.00
6f6iB-5n6vA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_G_ZOLG401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)		 5n6v AMYLOSUCRASE
(Neisseria
polysaccharea) 		4 / 7 ASP A 507
ARG A 513
GLN A 254
TYR A 147
 None
None
TRS  A 701 (-4.2A)
TRS  A 701 (-3.5A)
 1.39A 6g31G-5n6vA:
undetectable		 6g31G-5n6vA:
23.26