SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5n6w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)
5n6w RETINOSCHISIN
(Homo
sapiens)
3 / 3 ASN A  85
ASP A 118
ARG A 156
None
0.87A 3k13A-5n6wA:
undetectable
3k13A-5n6wA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)
5n6w RETINOSCHISIN
(Homo
sapiens)
5 / 12 ILE A 212
SER A  94
ALA A  98
ILE A 125
VAL A  76
None
1.10A 3w67C-5n6wA:
undetectable
3w67C-5n6wA:
21.48