SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5n77'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8E_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 5n77 MAGNESIUM TRANSPORT
PROTEIN CORA
(Escherichia
coli) 		3 / 3 ARG A  14
ILE A  29
TRP A  28
 None
 1.23A 1m8eB-5n77A:
undetectable		 1m8eB-5n77A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 5n77 MAGNESIUM TRANSPORT
PROTEIN CORA
(Escherichia
coli) 		3 / 3 ARG A  14
ILE A  29
TRP A  28
 None
 1.11A 1nodB-5n77A:
undetectable		 1nodB-5n77A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5n77 MAGNESIUM TRANSPORT
PROTEIN CORA
(Escherichia
coli) 		3 / 3 VAL A  92
ALA A  93
HIS A  73
 None
 0.69A 1q23G-5n77A:
undetectable		 1q23G-5n77A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5n77 MAGNESIUM TRANSPORT
PROTEIN CORA
(Escherichia
coli) 		3 / 3 VAL A  92
ALA A  93
HIS A  73
 None
 0.64A 1q23J-5n77A:
undetectable		 1q23J-5n77A:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QOM_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 5n77 MAGNESIUM TRANSPORT
PROTEIN CORA
(Escherichia
coli) 		3 / 3 ARG A  14
ILE A  29
TRP A  28
 None
 1.05A 1qomA-5n77A:
undetectable		 1qomA-5n77A:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN0_C_T44C601_1
(TRANSTHYRETIN)		 5n77 MAGNESIUM TRANSPORT
PROTEIN CORA
(Escherichia
coli) 		5 / 9 LEU A  23
LEU A  46
LYS A   1
LEU A  31
ALA A   4
 None
 1.41A 1sn0A-5n77A:
undetectable
1sn0C-5n77A:
undetectable		 1sn0A-5n77A:
18.50
1sn0C-5n77A:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 5n77 MAGNESIUM TRANSPORT
PROTEIN CORA
(Escherichia
coli) 		3 / 3 ARG A  14
ILE A  29
TRP A  28
 None
 1.05A 2nodB-5n77A:
undetectable		 2nodB-5n77A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZIA_B_CL9B401_2
(DEOXYCYTIDINE KINASE)		 5n77 MAGNESIUM TRANSPORT
PROTEIN CORA
(Escherichia
coli) 		4 / 4 ARG A 197
ASP A 194
LEU A 227
ARG A 204
 None
 1.46A 2ziaB-5n77A:
undetectable		 2ziaB-5n77A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E68_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5n77 MAGNESIUM TRANSPORT
PROTEIN CORA
(Escherichia
coli) 		3 / 3 ARG A  14
ILE A  29
TRP A  28
 None
 1.18A 3e68A-5n77A:
undetectable		 3e68A-5n77A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E6T_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5n77 MAGNESIUM TRANSPORT
PROTEIN CORA
(Escherichia
coli) 		3 / 3 ARG A  14
ILE A  29
TRP A  28
 None
 1.17A 3e6tB-5n77A:
undetectable		 3e6tB-5n77A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7I_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5n77 MAGNESIUM TRANSPORT
PROTEIN CORA
(Escherichia
coli) 		3 / 3 ARG A  14
ILE A  29
TRP A  28
 None
 1.10A 3e7iB-5n77A:
undetectable		 3e7iB-5n77A:
22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5n77 MAGNESIUM TRANSPORT
PROTEIN CORA
(Escherichia
coli) 		3 / 3 ARG A  14
ILE A  29
TRP A  28
 None
 1.06A 3nw2A-5n77A:
undetectable		 3nw2A-5n77A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5n77 MAGNESIUM TRANSPORT
PROTEIN CORA
(Escherichia
coli) 		3 / 3 ARG A  14
ILE A  29
TRP A  28
 None
 1.03A 3nw2B-5n77A:
undetectable		 3nw2B-5n77A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QC6_B_KANB201_1
(BIFUNCTIONAL AAC/APH)		 5n77 MAGNESIUM TRANSPORT
PROTEIN CORA
(Escherichia
coli) 		5 / 12 GLY A 127
TYR A 115
GLU A 138
ARG A 118
GLN A 122
 None
 1.22A 4qc6B-5n77A:
undetectable		 4qc6B-5n77A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWZ_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5n77 MAGNESIUM TRANSPORT
PROTEIN CORA
(Escherichia
coli) 		3 / 3 MET A 124
GLN A 122
ARG A  11
 None
 0.69A 5ewzB-5n77A:
4.2		 5ewzB-5n77A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UOC_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5n77 MAGNESIUM TRANSPORT
PROTEIN CORA
(Escherichia
coli) 		4 / 5 VAL A  32
ARG A  14
TRP A  28
PHE A   5
 None
 1.43A 5uocC-5n77A:
0.0
5uocD-5n77A:
0.0		 5uocC-5n77A:
21.06
5uocD-5n77A:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5n77 MAGNESIUM TRANSPORT
PROTEIN CORA
(Escherichia
coli) 		4 / 6 VAL A  32
ARG A  14
TRP A  28
PHE A   5
 None
 1.28A 6av6C-5n77A:
undetectable
6av6D-5n77A:
0.0		 6av6C-5n77A:
13.93
6av6D-5n77A:
13.93