SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5n7q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D0V_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		4 / 8 GLY A  96
GLY A 175
PHE A 174
GLY A   4
 None
 0.69A 1d0vA-5n7qA:
undetectable		 1d0vA-5n7qA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHA_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		4 / 8 GLY A  96
GLY A 175
PHE A 174
GLY A   4
 None
 0.72A 1jhaA-5n7qA:
undetectable		 1jhaA-5n7qA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_1
(POL POLYPROTEIN)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		5 / 9 LEU A 160
ASP A 316
ILE A 225
GLY A  38
VAL A 158
 None
 0.93A 2avoA-5n7qA:
6.0		 2avoA-5n7qA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1122_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		4 / 7 SER A  46
LYS A  48
SER A  89
SER A  62
 None
 1.25A 2j9cA-5n7qA:
undetectable
2j9cB-5n7qA:
1.2
2j9cC-5n7qA:
undetectable		 2j9cA-5n7qA:
undetectable
2j9cB-5n7qA:
undetectable
2j9cC-5n7qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1122_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		4 / 7 SER A  89
SER A  62
SER A  46
LYS A  48
 None
 1.33A 2j9cA-5n7qA:
undetectable
2j9cB-5n7qA:
1.2
2j9cC-5n7qA:
undetectable		 2j9cA-5n7qA:
undetectable
2j9cB-5n7qA:
undetectable
2j9cC-5n7qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A131_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		4 / 6 LEU A  44
ASN A 143
ILE A  22
PHE A  31
 None
 1.24A 2jn3A-5n7qA:
undetectable		 2jn3A-5n7qA:
23.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_C_D16C509_1
(THYMIDYLATE SYNTHASE)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		5 / 10 ASP A 316
LEU A 319
GLY A 315
PHE A 318
TYR A  18
 None
 1.46A 2tsrC-5n7qA:
undetectable		 2tsrC-5n7qA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_B_CLMB1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		5 / 11 ALA A 226
VAL A 201
GLY A 315
ILE A 233
VAL A 204
 None
 1.18A 2uxpB-5n7qA:
undetectable		 2uxpB-5n7qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_C_C41C1328_1
(RENIN)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		8 / 12 ASP A  36
GLY A  38
SER A  39
TYR A  79
PHE A 121
ASP A 227
GLY A 229
SER A 231
 None
 0.51A 2v0zC-5n7qA:
45.9		 2v0zC-5n7qA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_O_C41O1327_1
(RENIN)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		7 / 12 ASP A  36
GLY A  38
ALA A 119
PHE A 121
ASP A 227
GLY A 229
SER A 231
 None
 0.66A 2v0zO-5n7qA:
45.2		 2v0zO-5n7qA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X91_A_LPRA1615_2
(ANGIOTENSIN
CONVERTING ENZYME)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		3 / 3 SER A 231
THR A 234
PHE A 199
 None
 0.73A 2x91A-5n7qA:
undetectable		 2x91A-5n7qA:
10.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BMC_D_FOLD270_0
(PTERIDINE REDUCTASE)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		5 / 12 PHE A 318
PHE A 335
TYR A 322
VAL A 204
GLU A 223
 None
 1.46A 3bmcD-5n7qA:
undetectable		 3bmcD-5n7qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_A_REMA350_1
(RENIN)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		5 / 12 ASP A  36
GLY A  38
PHE A 121
ASP A 227
SER A 231
 None
 0.53A 3d91A-5n7qA:
45.7		 3d91A-5n7qA:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW3_A_TOPA208_1
(DIHYDROFOLATE
REDUCTASE)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		5 / 10 ALA A  98
VAL A 140
ILE A  24
LEU A 105
ILE A  22
 None
 1.08A 3jw3A-5n7qA:
undetectable		 3jw3A-5n7qA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW3_B_TOPB208_1
(DIHYDROFOLATE
REDUCTASE)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		5 / 9 ALA A  98
VAL A 140
ILE A  24
LEU A 105
ILE A  22
 None
 1.16A 3jw3B-5n7qA:
undetectable		 3jw3B-5n7qA:
17.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUV_A_ASDA126_1
(STEROID
DELTA-ISOMERASE)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		5 / 12 LEU A 319
PHE A 156
PHE A 335
VAL A 333
ALA A 128
 None
 1.30A 3nuvA-5n7qA:
undetectable		 3nuvA-5n7qA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OCT_A_1N1A663_2
(TYROSINE-PROTEIN
KINASE BTK)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		4 / 5 PHE A 174
ILE A 177
MET A 145
ASN A 143
 None
 1.28A 3octA-5n7qA:
undetectable		 3octA-5n7qA:
16.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_A_478A200_1
(HIV-1 PROTEASE)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		4 / 6 GLU A  85
TRP A  43
PRO A  45
GLY A  86
 None
 1.12A 3oxvA-5n7qA:
6.3		 3oxvA-5n7qA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PRS_A_RITA1001_2
(ENDOTHIAPEPSIN)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		6 / 12 ASP A  36
GLY A  38
GLY A  80
ASP A 227
THR A 230
ILE A 313
 None
 0.47A 3prsA-5n7qA:
39.9		 3prsA-5n7qA:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_1
(ENDOTHIAPEPSIN)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		5 / 12 ASP A  36
GLY A  80
ILE A 225
THR A 230
ILE A 313
 None
 0.52A 3pwwA-5n7qA:
39.7		 3pwwA-5n7qA:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWW_A_ROCA1001_2
(ENDOTHIAPEPSIN)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		5 / 8 GLY A  38
SER A  39
ILE A  77
TYR A  79
ASP A 227
 None
 0.33A 3pwwA-5n7qA:
39.7		 3pwwA-5n7qA:
13.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_1
(CANDIDAPEPSIN-2)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		7 / 12 ILE A  34
ASP A  36
GLY A  38
GLY A  80
ASP A 227
THR A 230
ILE A 313
 None
 0.38A 3q70A-5n7qA:
36.1		 3q70A-5n7qA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_1
(CANDIDAPEPSIN-2)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		6 / 12 ILE A 124
ASP A  36
GLY A  38
ASP A 227
THR A 230
ILE A 313
 None
 1.22A 3q70A-5n7qA:
36.1		 3q70A-5n7qA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_1
(CANDIDAPEPSIN-2)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		6 / 12 ILE A 124
ASP A  36
ILE A  77
ASP A 227
THR A 230
ILE A 313
 None
 1.38A 3q70A-5n7qA:
36.1		 3q70A-5n7qA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q70_A_RITA2001_1
(CANDIDAPEPSIN-2)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		6 / 12 ILE A 225
ASP A 227
GLY A 229
GLY A  80
ASP A  36
ILE A 124
 None
 0.80A 3q70A-5n7qA:
36.1		 3q70A-5n7qA:
11.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SOA_A_DB8A445_1
(CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II
SUBUNIT ALPHA WITH A
BETA 7 LINKER)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		4 / 6 LEU A 281
VAL A 270
PHE A 302
VAL A 317
 None
 1.15A 3soaA-5n7qA:
undetectable		 3soaA-5n7qA:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_4
(PROTEASE)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		4 / 4 ASP A 329
ASP A 327
GLY A 176
THR A 324
 None
 1.29A 3tl9B-5n7qA:
6.8		 3tl9B-5n7qA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_1
(SECRETED ASPARTIC
PROTEASE)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		6 / 12 ILE A  34
ASP A  36
GLY A  38
ILE A  77
ASP A 227
ILE A 225
 None
 1.45A 3tneA-5n7qA:
37.4		 3tneA-5n7qA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_1
(SECRETED ASPARTIC
PROTEASE)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		7 / 12 ILE A  34
ASP A  36
GLY A  38
ILE A  77
GLY A  80
ASP A 227
ILE A 313
 None
 0.57A 3tneA-5n7qA:
37.4		 3tneA-5n7qA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_1
(SECRETED ASPARTIC
PROTEASE)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		5 / 12 ILE A 225
ASP A 227
GLY A 229
ASP A  36
ILE A 124
 None
 0.69A 3tneA-5n7qA:
37.4		 3tneA-5n7qA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_A_RITA401_1
(SECRETED ASPARTIC
PROTEASE)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		5 / 12 ILE A 225
ASP A 227
GLY A 229
GLY A  80
ASP A  36
 None
 0.76A 3tneA-5n7qA:
37.4		 3tneA-5n7qA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		6 / 12 ILE A  34
ASP A  36
GLY A  38
ILE A  77
ASP A 227
ILE A 225
 None
 1.50A 3tneB-5n7qA:
37.3		 3tneB-5n7qA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		7 / 12 ILE A  34
ASP A  36
GLY A  38
ILE A  77
GLY A  80
ASP A 227
ILE A 313
 None
 0.61A 3tneB-5n7qA:
37.3		 3tneB-5n7qA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		5 / 12 ILE A 225
ASP A 227
GLY A 229
ASP A  36
ILE A 124
 None
 0.71A 3tneB-5n7qA:
37.3		 3tneB-5n7qA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_1
(SECRETED ASPARTIC
PROTEASE)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		5 / 12 ILE A 225
ASP A 227
GLY A 229
GLY A  80
ASP A  36
 None
 0.74A 3tneB-5n7qA:
37.3		 3tneB-5n7qA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TNE_B_RITB401_2
(SECRETED ASPARTIC
PROTEASE)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		4 / 7 SER A  39
TYR A  79
ILE A 124
THR A 230
 None
 0.37A 3tneB-5n7qA:
37.3		 3tneB-5n7qA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_E_ZPCE1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		4 / 8 VAL A 155
ARG A 332
ILE A 325
GLU A 152
 None
 0.90A 4a97D-5n7qA:
undetectable		 4a97D-5n7qA:
16.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_A_SAMA401_0
(METHYLTRANSFERASE
NSUN4)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		5 / 12 PRO A   5
GLY A 175
GLY A 176
SER A  97
PRO A   9
 None
 1.00A 4fp9A-5n7qA:
undetectable		 4fp9A-5n7qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_C_SAMC401_0
(METHYLTRANSFERASE
NSUN4)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		5 / 12 PRO A   5
GLY A 175
GLY A 176
SER A  97
PRO A   9
 None
 0.99A 4fp9C-5n7qA:
undetectable		 4fp9C-5n7qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_0
(METHYLTRANSFERASE
NSUN4)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		5 / 12 PRO A   5
GLY A 175
GLY A 176
SER A  97
PRO A   9
 None
 0.99A 4fp9D-5n7qA:
undetectable		 4fp9D-5n7qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_F_SAMF401_0
(METHYLTRANSFERASE
NSUN4)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		5 / 12 PRO A   5
GLY A 175
GLY A 176
SER A  97
PRO A   9
 None
 0.98A 4fp9F-5n7qA:
undetectable		 4fp9F-5n7qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_0
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		5 / 12 PRO A   5
GLY A 175
GLY A 176
SER A  97
PRO A   9
 None
 0.97A 4fzvA-5n7qA:
undetectable		 4fzvA-5n7qA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_2
(SUGAR KINASE)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		3 / 3 SER A  39
TYR A  79
PRO A 139
 None
 0.80A 4k8cA-5n7qA:
undetectable		 4k8cA-5n7qA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		3 / 3 SER A  39
TYR A  79
PRO A 139
 None
 0.80A 4kahA-5n7qA:
undetectable		 4kahA-5n7qA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		3 / 3 SER A  39
TYR A  79
PRO A 139
 None
 0.80A 4kahB-5n7qA:
undetectable		 4kahB-5n7qA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		3 / 3 SER A  39
TYR A  79
PRO A 139
 None
 0.79A 4kanA-5n7qA:
undetectable		 4kanA-5n7qA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		3 / 3 SER A  39
TYR A  79
PRO A 139
 None
 0.81A 4kanB-5n7qA:
undetectable		 4kanB-5n7qA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		3 / 3 SER A  39
TYR A  79
PRO A 139
 None
 0.84A 4kbeA-5n7qA:
undetectable		 4kbeA-5n7qA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		3 / 3 SER A  39
TYR A  79
PRO A 139
 None
 0.81A 4kbeB-5n7qA:
undetectable		 4kbeB-5n7qA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		3 / 3 SER A  39
TYR A  79
PRO A 139
 None
 0.80A 4lbgA-5n7qA:
undetectable		 4lbgA-5n7qA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		3 / 3 SER A  39
TYR A  79
PRO A 139
 None
 0.79A 4lbgB-5n7qA:
undetectable		 4lbgB-5n7qA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA303_1
(CHITOSANASE)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		4 / 6 ILE A 313
ASP A 227
GLY A  80
VAL A  78
 None
 0.84A 4oltA-5n7qA:
undetectable		 4oltA-5n7qA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB303_1
(CHITOSANASE)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		4 / 6 ILE A 313
ASP A 227
GLY A  80
VAL A  78
 None
 0.84A 4oltB-5n7qA:
undetectable		 4oltB-5n7qA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_A_LURA705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		5 / 12 VAL A 270
LEU A 281
LEU A 232
GLY A 301
LEU A 247
 None
 1.06A 4otyA-5n7qA:
undetectable		 4otyA-5n7qA:
8.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OTY_B_LURB705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		5 / 12 VAL A 270
LEU A 281
LEU A 232
GLY A 301
LEU A 247
 None
 0.99A 4otyB-5n7qA:
undetectable		 4otyB-5n7qA:
8.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		3 / 3 PRO A  45
LEU A  44
GLN A  29
 None
 0.68A 4pevB-5n7qA:
undetectable		 4pevB-5n7qA:
13.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q5M_A_ROCA1101_3
(PROTEASE)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		3 / 3 ASP A 227
ASP A  36
ASN A  41
 None
 0.55A 4q5mA-5n7qA:
10.0		 4q5mA-5n7qA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRW_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		5 / 12 VAL A 270
LEU A 281
LEU A 232
GLY A 301
LEU A 247
 None
 1.02A 4rrwD-5n7qA:
undetectable		 4rrwD-5n7qA:
8.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RRZ_D_LURD705_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		5 / 12 VAL A 270
LEU A 281
LEU A 232
GLY A 301
LEU A 247
 None
 1.02A 4rrzD-5n7qA:
undetectable		 4rrzD-5n7qA:
8.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GSN_A_MMZA503_1
(FLAVIN-CONTAINING
MONOOXYGENASE)		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		3 / 3 ASN A 161
SER A 166
SER A 165
 None
 0.79A 5gsnA-5n7qA:
undetectable		 5gsnA-5n7qA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUI_B_CTCB405_0
(TETRACYCLINE
DESTRUCTASE TET(50))		 5n7q PUTATIVE CATHEPSIN D
(Ixodes
ricinus) 		5 / 12 VAL A  84
GLY A 126
PHE A  35
VAL A  33
ILE A  22
 None
 0.98A 5tuiB-5n7qA:
undetectable		 5tuiB-5n7qA:
undetectable