SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5n7s'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CR1_A_T44A201_1
(TRANSTHYRETIN)		 5n7s TYPE II SECRETION
SYSTEM PROTEIN L
(Pseudomonas
aeruginosa) 		4 / 5 LEU B 378
ALA B 376
LEU B 338
VAL B 374
 None
 1.05A 5cr1A-5n7sB:
undetectable		 5cr1A-5n7sB:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC3_B_486B801_1
(GLUCOCORTICOID
RECEPTOR)		 5n7s TYPE II SECRETION
SYSTEM PROTEIN L
(Pseudomonas
aeruginosa) 		5 / 12 LEU B 305
GLY B 381
VAL B 362
ARG B 333
PHE B 329
 None
 1.46A 5uc3B-5n7sB:
undetectable		 5uc3B-5n7sB:
26.74