SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5n7z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQB_B_BEZB525_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5n7z LIPOPOLYSACCHARIDE
1,6-GALACTOSYLTRANSF
ERASE
(Salmonella
enterica) 		4 / 5 GLU A 268
GLY A 292
THR A 273
PHE A 270
 None
 1.18A 1kqbA-5n7zA:
undetectable
1kqbB-5n7zA:
undetectable		 1kqbA-5n7zA:
undetectable
1kqbB-5n7zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_A_THAA1_1
(LIVER
CARBOXYLESTERASE I)		 5n7z LIPOPOLYSACCHARIDE
1,6-GALACTOSYLTRANSF
ERASE
(Salmonella
enterica) 		5 / 11 GLY A 292
LEU A 305
LEU A 274
LEU A 275
MET A 278
 None
 1.04A 1mx1A-5n7zA:
undetectable		 1mx1A-5n7zA:
8.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DM6_A_IMNA1401_1
(NADP-DEPENDENT
LEUKOTRIENE B4
12-HYDROXYDEHYDROGEN
ASE)		 5n7z LIPOPOLYSACCHARIDE
1,6-GALACTOSYLTRANSF
ERASE
(Salmonella
enterica) 		5 / 10 ILE A 114
ALA A 134
ILE A 353
PRO A  87
ILE A  89
 None
 1.38A 2dm6A-5n7zA:
4.6
2dm6B-5n7zA:
3.9		 2dm6A-5n7zA:
15.00
2dm6B-5n7zA:
15.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_A_BRLA1_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 5n7z LIPOPOLYSACCHARIDE
1,6-GALACTOSYLTRANSF
ERASE
(Salmonella
enterica) 		5 / 12 PHE A 222
CYH A 225
GLN A 226
SER A 229
LEU A 200
 None
 1.09A 2prgA-5n7zA:
undetectable		 2prgA-5n7zA:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CV9_A_VDXA501_1
(CYTOCHROME P450-SU1)		 5n7z LIPOPOLYSACCHARIDE
1,6-GALACTOSYLTRANSF
ERASE
(Salmonella
enterica) 		5 / 9 THR A 336
SER A 142
LEU A 305
SER A 291
ILE A 333
 None
 1.21A 3cv9A-5n7zA:
undetectable		 3cv9A-5n7zA:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_B_H3PB552_1
(GLUTAMATE
DEHYDROGENASE)		 5n7z LIPOPOLYSACCHARIDE
1,6-GALACTOSYLTRANSF
ERASE
(Salmonella
enterica) 		3 / 3 TYR A 280
TYR A 341
ILE A 167
 None
 0.69A 3eteA-5n7zA:
2.0
3eteB-5n7zA:
undetectable		 3eteA-5n7zA:
9.88
3eteB-5n7zA:
9.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_F_ACTF402_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 5n7z LIPOPOLYSACCHARIDE
1,6-GALACTOSYLTRANSF
ERASE
(Salmonella
enterica) 		3 / 3 PHE A 314
ASP A 312
ARG A 206
 None
 0.85A 4eahF-5n7zA:
undetectable		 4eahF-5n7zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_G_ACTG401_0
(ACTIN, ALPHA
SKELETAL MUSCLE)		 5n7z LIPOPOLYSACCHARIDE
1,6-GALACTOSYLTRANSF
ERASE
(Salmonella
enterica) 		3 / 3 PHE A 314
ASP A 312
ARG A 206
 None
 0.84A 4eahG-5n7zA:
undetectable		 4eahG-5n7zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 5n7z LIPOPOLYSACCHARIDE
1,6-GALACTOSYLTRANSF
ERASE
(Salmonella
enterica) 		4 / 8 LEU A 122
ILE A 158
VAL A 160
GLY A 143
 None
 0.78A 4eq4B-5n7zA:
undetectable		 4eq4B-5n7zA:
9.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_2
(THYROXINE-BINDING
GLOBULIN)		 5n7z LIPOPOLYSACCHARIDE
1,6-GALACTOSYLTRANSF
ERASE
(Salmonella
enterica) 		3 / 3 LEU A  69
ARG A  71
ARG A  70
 None
 0.90A 4yiaB-5n7zA:
undetectable		 4yiaB-5n7zA:
13.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4I_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 5n7z LIPOPOLYSACCHARIDE
1,6-GALACTOSYLTRANSF
ERASE
(Salmonella
enterica) 		3 / 3 VAL A  75
ALA A 101
PHE A  41
 None
 0.78A 4z4iA-5n7zA:
5.6		 4z4iA-5n7zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)		 5n7z LIPOPOLYSACCHARIDE
1,6-GALACTOSYLTRANSF
ERASE
(Salmonella
enterica) 		4 / 6 ILE A  55
GLY A  14
ILE A  20
TRP A  51
 None
 0.86A 5j4nB-5n7zA:
undetectable		 5j4nB-5n7zA:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS1_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5n7z LIPOPOLYSACCHARIDE
1,6-GALACTOSYLTRANSF
ERASE
(Salmonella
enterica) 		3 / 3 VAL A  75
ALA A 101
PHE A  41
 None
 0.78A 5js1A-5n7zA:
undetectable		 5js1A-5n7zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA820_0
(GEPHYRIN)		 5n7z LIPOPOLYSACCHARIDE
1,6-GALACTOSYLTRANSF
ERASE
(Salmonella
enterica) 		4 / 5 GLU A 268
PRO A 271
THR A 273
MET A 296
 None
 1.44A 6fgdA-5n7zA:
2.3		 6fgdA-5n7zA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_1
(-)		 5n7z LIPOPOLYSACCHARIDE
1,6-GALACTOSYLTRANSF
ERASE
(Salmonella
enterica) 		5 / 12 GLU A  17
GLY A  14
GLY A  15
VAL A  19
ASN A 163
 None
 0.82A 6gneB-5n7zA:
24.0		 6gneB-5n7zA:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GSD_A_STRA401_0
(PROGESTERONE
5-BETA-REDUCTASE)		 5n7z LIPOPOLYSACCHARIDE
1,6-GALACTOSYLTRANSF
ERASE
(Salmonella
enterica) 		5 / 12 PHE A 115
ILE A  91
ASN A 350
SER A  30
ILE A   3
 None
 1.41A 6gsdA-5n7zA:
5.8		 6gsdA-5n7zA:
20.88