SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5n86'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3P2K_A_SAMA6735_1 (16S RRNA METHYLASE)	5n86	STABILIN-2 (Homo sapiens)	3 / 3	ASP A 65 GLU A 59 SER A 93	None	0.83A	3p2kA-5n86A: undetectable	3p2kA-5n86A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DZK_P_BEZP801_0 (ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2 BEZ-LEU-LEU)	5n86	STABILIN-2 (Homo sapiens)	4 / 5	SER A 125 ALA A 124 MET A 75 LEU A 41	None	1.35A	5dzkb-5n86A: undetectable 5dzkp-5n86A: undetectable	5dzkb-5n86A: undetectable 5dzkp-5n86A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5J4N_A_AG2A501_1 (ARGININE/AGMATINE ANTIPORTER)	5n86	STABILIN-2 (Homo sapiens)	4 / 6	SER A 1 GLY A 127 ASN A 126 ILE A 122	None	1.16A	5j4nA-5n86A: undetectable	5j4nA-5n86A: 11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KKZ_O_ASCO1004_0 (CYTOCHROME B UBIQUINOL-CYTOCHROME C REDUCTASE IRON-SULFUR SUBUNIT)	5n86	STABILIN-2 (Homo sapiens)	4 / 7	HIS A 69 HIS A 130 ILE A 132 VAL A 131	None	1.09A	5kkzM-5n86A: 0.5 5kkzO-5n86A: undetectable	5kkzM-5n86A: undetectable 5kkzO-5n86A: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3P2K_A_SAMA6735_1","16S RRNA METHYLASE","5n86","STABILIN-2","Homo sapiens",3,"ASP A  65;GLU A  59;SER A  93","None","0.83A","3p2kA-5n86A:undetectable","3p2kA-5n86A:undetectable"],["5DZK_P_BEZP801_0","ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 2;BEZ-LEU-LEU","5n86","STABILIN-2","Homo sapiens",4,"SER A 125;ALA A 124;MET A  75;LEU A  41","None","1.35A","5dzkb-5n86A:undetectable;5dzkp-5n86A:undetectable","5dzkb-5n86A:undetectable;5dzkp-5n86A:undetectable"],["5J4N_A_AG2A501_1","ARGININE\/AGMATINE ANTIPORTER","5n86","STABILIN-2","Homo sapiens",4,"SER A   1;GLY A 127;ASN A 126;ILE A 122","None","1.16A","5j4nA-5n86A:undetectable","5j4nA-5n86A:11.98"],["5KKZ_O_ASCO1004_0","CYTOCHROME B;UBIQUINOL-CYTOCHROME C REDUCTASE IRON-SULFUR SUBUNIT","5n86","STABILIN-2","Homo sapiens",4,"HIS A  69;HIS A 130;ILE A 132;VAL A 131","None","1.09A","5kkzM-5n86A:0.5;5kkzO-5n86A:undetectable","5kkzM-5n86A:undetectable;5kkzO-5n86A:undetectable"]]