SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5n8d'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_1
(CELLULAR
RETINOL-BINDING
PROTEIN II)		 5n8d FIBER
(Murine
mastadenovirus
B) 		4 / 7 GLN A 744
THR A 746
TYR A 747
GLN A 683
 None
None
None
GOL  A 801 (-4.0A)
 1.35A 1eiiA-5n8dA:
undetectable		 1eiiA-5n8dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT4_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5n8d FIBER
(Murine
mastadenovirus
B) 		5 / 12 LEU A 697
LEU A 687
ALA A 654
ALA A 656
MET A 643
 None
 1.34A 1kt4A-5n8dA:
undetectable		 1kt4A-5n8dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT5_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5n8d FIBER
(Murine
mastadenovirus
B) 		5 / 12 LEU A 697
LEU A 687
ALA A 654
ALA A 656
MET A 643
 None
 1.31A 1kt5A-5n8dA:
undetectable		 1kt5A-5n8dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2002_1
(SERUM ALBUMIN)		 5n8d FIBER
(Murine
mastadenovirus
B) 		5 / 11 ILE A 658
LEU A 687
TYR A 635
ARG A 700
GLY A 699
 None
 1.37A 2bxmA-5n8dA:
undetectable		 2bxmA-5n8dA:
7.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5n8d FIBER
(Murine
mastadenovirus
B) 		4 / 8 THR A 721
ASP A 723
SER A 725
TYR A 727
 None
 1.39A 2xz5A-5n8dA:
undetectable
2xz5C-5n8dA:
undetectable		 2xz5A-5n8dA:
undetectable
2xz5C-5n8dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP1_A_ACTA590_0
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 5n8d FIBER
(Murine
mastadenovirus
B) 		4 / 5 GLU A 710
LEU A 711
GLN A 636
GLY A 705
 None
CL  A 803 ( 4.3A)
None
None
 1.22A 3pp1A-5n8dA:
undetectable		 3pp1A-5n8dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA302_0
(THAUMATIN-1)		 5n8d FIBER
(Murine
mastadenovirus
B) 		3 / 3 ARG A 755
GLN A 688
GLU A 686
 None
 0.81A 4tvtA-5n8dA:
undetectable		 4tvtA-5n8dA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W4Z_B_RBFB502_2
(RIBOFLAVIN LYASE)		 5n8d FIBER
(Murine
mastadenovirus
B) 		4 / 4 ASN A 758
GLN A 688
ASP A 690
THR A 714
 None
 1.44A 5w4zB-5n8dA:
undetectable		 5w4zB-5n8dA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YCP_A_BRLA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5n8d FIBER
(Murine
mastadenovirus
B) 		3 / 3 GLY A 694
VAL A 667
MET A 660
 None
 0.59A 5ycpA-5n8dA:
undetectable		 5ycpA-5n8dA:
17.98