SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5n94'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_A_THAA1_1
(LIVER
CARBOXYLESTERASE I)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		5 / 11 LEU A 645
PHE A 746
GLY A 628
LEU A 624
LEU A 634
 None
 1.12A 1mx1A-5n94A:
undetectable		 1mx1A-5n94A:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		3 / 3 ARG A 688
ASP A 654
ASN A 751
 None
 0.63A 1nbhA-5n94A:
4.8		 1nbhA-5n94A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		3 / 3 ARG A 688
ASP A 654
ASN A 751
 None
 0.66A 1nbhD-5n94A:
4.8		 1nbhD-5n94A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AKE_A_TRPA479_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		5 / 12 TYR A 253
THR A 252
GLY A 235
GLY A 231
GLU A 228
 None
 1.28A 2akeA-5n94A:
undetectable		 2akeA-5n94A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		5 / 12 ILE A 297
LEU A 263
LEU A 259
THR A 256
THR A 208
 None
 0.97A 2aw1A-5n94A:
undetectable		 2aw1A-5n94A:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		5 / 12 THR A 312
GLY A 176
SER A 177
GLY A 332
ILE A 162
 None
 1.16A 2b25B-5n94A:
undetectable		 2b25B-5n94A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FB2_A_SAMA501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		4 / 8 TYR A 253
CYH A 207
THR A 155
VAL A 222
 None
 1.07A 2fb2A-5n94A:
undetectable		 2fb2A-5n94A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZJ0_A_2FAA500_2
(ADENOSYLHOMOCYSTEINA
SE)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		4 / 5 THR A 513
THR A 489
HIS A 463
LEU A 465
 U  C   3 ( 2.9A)
U  C   4 ( 2.9A)
U  C   4 ( 3.8A)
U  C   2 ( 4.3A)
 1.39A 2zj0A-5n94A:
3.6		 2zj0A-5n94A:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		3 / 3 VAL A 306
LYS A 305
HIS A 300
 None
 0.94A 3elzA-5n94A:
undetectable		 3elzA-5n94A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		4 / 7 ILE A  52
LYS A 876
TYR A 866
GLY A  55
 None
 0.82A 3em0B-5n94A:
undetectable		 3em0B-5n94A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_B_PNNB301_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		5 / 12 CYH A 180
GLY A 179
GLY A 332
SER A 177
GLY A 176
 None
 1.02A 3huoB-5n94A:
undetectable		 3huoB-5n94A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_4
(HIV-1 PROTEASE)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		3 / 3 ARG A 555
VAL A 529
THR A 534
 None
 0.80A 3k4vD-5n94A:
undetectable		 3k4vD-5n94A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OCT_A_1N1A663_2
(TYROSINE-PROTEIN
KINASE BTK)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		4 / 5 PHE A 845
ILE A 770
MET A 690
ASN A 689
 None
 1.33A 3octA-5n94A:
undetectable		 3octA-5n94A:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_2
(HIV-1 PROTEASE)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		5 / 10 ALA A 858
VAL A 885
ILE A 850
GLY A 855
ILE A 886
 None
 1.10A 3oxvB-5n94A:
undetectable		 3oxvB-5n94A:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_2
(HIV-1 PROTEASE)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		5 / 11 ALA A 858
VAL A 885
ILE A 850
GLY A 855
ILE A 886
 None
 1.02A 3oxvD-5n94A:
undetectable		 3oxvD-5n94A:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQ9_A_MTXA2001_1
(DIHYDROFOLATE
REDUCTASE)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		5 / 12 LEU A 260
LEU A 293
ILE A 577
LEU A 593
ILE A 569
 None
 1.00A 3tq9A-5n94A:
undetectable		 3tq9A-5n94A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQB_A_FOLA2001_0
(DIHYDROFOLATE
REDUCTASE)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		5 / 11 LEU A 260
LEU A 293
ILE A 577
LEU A 593
ILE A 569
 None
 1.08A 3tqbA-5n94A:
undetectable		 3tqbA-5n94A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ASCA904_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		4 / 6 LEU A 673
PRO A 672
GLU A 676
SER A 671
 None
None
U  C   2 ( 4.4A)
U  C   2 ( 3.3A)
 1.29A 3vlnA-5n94A:
undetectable		 3vlnA-5n94A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_TESA1000_1
(ANDROGEN RECEPTOR)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		5 / 12 LEU A 618
LEU A 612
LEU A 611
GLN A 639
THR A 625
 None
 1.33A 3zqtA-5n94A:
undetectable		 3zqtA-5n94A:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		4 / 8 ASP A 499
ILE A 498
PHE A 475
GLY A 469
 None
 0.81A 4acaC-5n94A:
3.5		 4acaC-5n94A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K38_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		5 / 12 CYH A 717
PHE A 716
GLU A 470
LEU A 730
ILE A 701
 None
 1.50A 4k38B-5n94A:
undetectable		 4k38B-5n94A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KUK_A_RBFA201_2
(BLUE-LIGHT
PHOTORECEPTOR)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		5 / 9 LEU A 426
VAL A 413
ILE A 416
ILE A 505
GLY A 547
 None
 0.81A 4kukA-5n94A:
undetectable		 4kukA-5n94A:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		4 / 8 SER A 576
ASP A 637
GLU A 575
VAL A 285
 None
U  C   7 ( 4.8A)
None
None
 1.13A 4lnwA-5n94A:
undetectable		 4lnwA-5n94A:
15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_2
(TRANSPORTER)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		3 / 3 SER A 692
MET A 690
ASP A 680
 None
 0.78A 4mm4B-5n94A:
undetectable		 4mm4B-5n94A:
8.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_1
(PROTEASE)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		5 / 11 ALA A 858
VAL A 885
ILE A 850
GLY A 855
ILE A 886
 None
 0.92A 4njtC-5n94A:
undetectable		 4njtC-5n94A:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		4 / 4 THR A 530
ARG A 537
GLU A 493
VAL A 529
 None
 1.21A 4odoC-5n94A:
undetectable		 4odoC-5n94A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_E_CHDE104_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		5 / 11 LEU A 259
GLU A 286
LEU A 290
LEU A 277
LEU A 275
 None
U  C   6 ( 4.9A)
None
None
None
 0.88A 4wg0C-5n94A:
undetectable
4wg0D-5n94A:
undetectable
4wg0E-5n94A:
undetectable		 4wg0C-5n94A:
undetectable
4wg0D-5n94A:
undetectable
4wg0E-5n94A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_G_CHDG103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		5 / 11 LEU A 259
GLU A 286
LEU A 290
LEU A 277
LEU A 275
 None
U  C   6 ( 4.9A)
None
None
None
 0.88A 4wg0E-5n94A:
undetectable
4wg0F-5n94A:
undetectable
4wg0G-5n94A:
undetectable		 4wg0E-5n94A:
undetectable
4wg0F-5n94A:
undetectable
4wg0G-5n94A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_L_CHDL103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		4 / 7 LEU A 277
LEU A 275
GLU A 286
LEU A 290
 None
None
U  C   6 ( 4.9A)
None
 0.82A 4wg0L-5n94A:
undetectable
4wg0M-5n94A:
undetectable		 4wg0L-5n94A:
undetectable
4wg0M-5n94A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_M_CHDM103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		5 / 11 LEU A 259
GLU A 286
LEU A 290
LEU A 277
LEU A 275
 None
U  C   6 ( 4.9A)
None
None
None
 0.62A 4wg0K-5n94A:
undetectable
4wg0L-5n94A:
undetectable
4wg0M-5n94A:
undetectable		 4wg0K-5n94A:
undetectable
4wg0L-5n94A:
undetectable
4wg0M-5n94A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_F_MN9F401_0
(N-ACETYLNEURAMINATE
LYASE)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		4 / 5 LEU A 392
ASP A 393
TYR A 379
LEU A 380
 None
 1.26A 4wozF-5n94A:
undetectable
4wozH-5n94A:
undetectable		 4wozF-5n94A:
undetectable
4wozH-5n94A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		4 / 4 GLY A 423
VAL A 544
PHE A 475
ILE A 498
 None
 1.10A 4xv2B-5n94A:
undetectable		 4xv2B-5n94A:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		4 / 8 THR A 256
LEU A 259
THR A 287
LEU A 290
 None
 0.68A 4z90F-5n94A:
undetectable
4z90G-5n94A:
undetectable
4z90H-5n94A:
undetectable
4z90I-5n94A:
undetectable
4z90J-5n94A:
undetectable		 4z90F-5n94A:
15.81
4z90G-5n94A:
15.81
4z90H-5n94A:
15.81
4z90I-5n94A:
15.81
4z90J-5n94A:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z90_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		4 / 8 THR A 287
LEU A 290
THR A 256
LEU A 259
 None
 0.64A 4z90F-5n94A:
undetectable
4z90G-5n94A:
undetectable
4z90H-5n94A:
undetectable
4z90I-5n94A:
undetectable
4z90J-5n94A:
undetectable		 4z90F-5n94A:
15.81
4z90G-5n94A:
15.81
4z90H-5n94A:
15.81
4z90I-5n94A:
15.81
4z90J-5n94A:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		4 / 5 VAL A 609
ILE A 564
PRO A 600
THR A 287
 None
 1.28A 4ze1A-5n94A:
undetectable		 4ze1A-5n94A:
10.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		4 / 7 ARG A 537
ARG A 557
GLY A 402
GLU A 401
 None
 0.83A 5btaA-5n94A:
undetectable
5btaC-5n94A:
undetectable
5btaD-5n94A:
3.0		 5btaA-5n94A:
10.42
5btaC-5n94A:
10.42
5btaD-5n94A:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		4 / 6 ARG A 557
GLY A 402
GLU A 401
ARG A 537
 None
 0.82A 5btaA-5n94A:
undetectable
5btaB-5n94A:
3.1
5btaC-5n94A:
undetectable		 5btaA-5n94A:
10.42
5btaB-5n94A:
17.99
5btaC-5n94A:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		4 / 6 ARG A 537
ARG A 557
GLY A 402
GLU A 401
 None
 0.89A 5btcA-5n94A:
undetectable
5btcC-5n94A:
undetectable
5btcD-5n94A:
3.1		 5btcA-5n94A:
10.42
5btcC-5n94A:
10.42
5btcD-5n94A:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		4 / 6 ARG A 557
GLY A 402
GLU A 401
ARG A 537
 None
 0.81A 5btcA-5n94A:
undetectable
5btcB-5n94A:
2.9
5btcC-5n94A:
undetectable		 5btcA-5n94A:
10.42
5btcB-5n94A:
17.99
5btcC-5n94A:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_F_GFNF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		4 / 7 ARG A 557
GLY A 402
GLU A 401
ARG A 537
 None
 0.87A 5btfA-5n94A:
undetectable
5btfB-5n94A:
3.0
5btfC-5n94A:
undetectable		 5btfA-5n94A:
10.42
5btfB-5n94A:
17.99
5btfC-5n94A:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		4 / 6 ARG A 557
GLY A 402
GLU A 401
ARG A 537
 None
 0.77A 5btgA-5n94A:
undetectable
5btgB-5n94A:
3.0
5btgC-5n94A:
undetectable		 5btgA-5n94A:
10.62
5btgB-5n94A:
17.99
5btgC-5n94A:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_V_MFXV2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		4 / 5 ARG A 557
GLY A 402
GLU A 401
ARG A 537
 None
 0.94A 5cdqR-5n94A:
undetectable
5cdqS-5n94A:
3.2
5cdqT-5n94A:
undetectable		 5cdqR-5n94A:
11.44
5cdqS-5n94A:
18.13
5cdqT-5n94A:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CPR_B_SAMB402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SUV420H1)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		5 / 12 TYR A 341
GLU A 343
ALA A 556
SER A 400
CYH A 549
 None
 1.30A 5cprB-5n94A:
undetectable		 5cprB-5n94A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_F_FK5F201_1
(FK506-BINDING
PROTEIN 1)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		5 / 12 ILE A 218
TYR A 253
ILE A 251
ILE A 205
ILE A 162
 None
 0.87A 5hw8B-5n94A:
undetectable
5hw8F-5n94A:
undetectable
5hw8G-5n94A:
undetectable		 5hw8B-5n94A:
18.85
5hw8F-5n94A:
18.85
5hw8G-5n94A:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC0_A_RBFA303_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		5 / 12 GLU A 616
ASP A 854
GLY A 853
ALA A 769
PHE A 650
 None
 1.32A 5kc0A-5n94A:
undetectable		 5kc0A-5n94A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M24_A_9CRA501_1
(RETINOIC ACID
RECEPTOR GAMMA)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		5 / 12 MET A 646
ILE A 770
SER A 761
PHE A 852
LEU A 888
 None
 1.04A 5m24A-5n94A:
undetectable		 5m24A-5n94A:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA510_1
(PROTON-GATED ION
CHANNEL)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		5 / 9 ALA A 604
ILE A 605
ILE A 569
ALA A 599
LEU A 593
 None
 0.94A 5mvmA-5n94A:
undetectable
5mvmE-5n94A:
undetectable		 5mvmA-5n94A:
20.93
5mvmE-5n94A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_E_PFLE409_1
(PROTON-GATED ION
CHANNEL)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		5 / 10 ILE A 569
ALA A 599
LEU A 593
ALA A 604
ILE A 605
 None
 1.01A 5mvmD-5n94A:
undetectable
5mvmE-5n94A:
undetectable		 5mvmD-5n94A:
20.93
5mvmE-5n94A:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUK_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		5 / 10 PHE A 460
ILE A 486
ILE A 498
PHE A 475
GLN A 471
 None
 1.21A 5nukA-5n94A:
undetectable		 5nukA-5n94A:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1803_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		5 / 10 LYS A 606
ILE A 605
ILE A 578
LEU A 612
ILE A 517
 None
 1.40A 5vkqA-5n94A:
undetectable
5vkqD-5n94A:
2.3		 5vkqA-5n94A:
undetectable
5vkqD-5n94A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		5 / 10 ILE A 517
LYS A 606
ILE A 605
ILE A 578
LEU A 612
 None
 1.43A 5vkqA-5n94A:
undetectable
5vkqB-5n94A:
undetectable		 5vkqA-5n94A:
undetectable
5vkqB-5n94A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1801_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		5 / 10 ILE A 517
LYS A 606
ILE A 605
ILE A 578
LEU A 612
 None
 1.40A 5vkqC-5n94A:
undetectable
5vkqD-5n94A:
2.3		 5vkqC-5n94A:
undetectable
5vkqD-5n94A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		4 / 6 MET A 466
GLU A 676
TYR A 432
GLY A 431
 None
U  C   2 ( 4.4A)
U  C   2 ( 3.5A)
U  C   3 ( 3.5A)
 0.81A 5x7pB-5n94A:
undetectable		 5x7pB-5n94A:
4.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XU8_A_DX4A701_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 2)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		4 / 8 GLY A 135
LEU A 134
GLN A 138
ALA A 143
 None
 0.91A 5xu8A-5n94A:
undetectable		 5xu8A-5n94A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA826_0
(GEPHYRIN)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		3 / 3 HIS A 698
ARG A 705
ILE A 701
 None
 0.88A 6fgdA-5n94A:
3.0		 6fgdA-5n94A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NCS_A_ACTA303_0
(N-ACETYLNEURAMINIC
ACID (SIALIC ACID)
SYNTHETASE)		 5n94 CG9323, ISOFORM A
(Drosophila
melanogaster) 		3 / 3 ILE A 251
THR A 252
PRO A 187
 None
 0.54A 6ncsA-5n94A:
undetectable		 6ncsA-5n94A:
undetectable