SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5n9m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
4 / 8 HIS A 179
GLY A 161
GLY A 177
LEU A 184
None
0.78A 1aegA-5n9mA:
undetectable
1aegA-5n9mA:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BSX_A_T3A1_1
(PROTEIN (THYROID
HORMONE RECEPTOR
BETA))
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
5 / 12 ILE A  24
ILE A  23
LEU A 204
ILE A  35
PHE A  57
None
1.05A 1bsxA-5n9mA:
undetectable
1bsxA-5n9mA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BSX_B_T3B2_1
(PROTEIN (THYROID
HORMONE RECEPTOR
BETA))
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
5 / 12 ILE A  24
ILE A  23
LEU A 204
ILE A  35
PHE A  57
None
1.06A 1bsxB-5n9mA:
undetectable
1bsxB-5n9mA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
4 / 7 LEU A  14
ASP A  19
TYR A  17
HIS A 155
None
1.07A 1v55C-5n9mA:
undetectable
1v55N-5n9mA:
undetectable
1v55P-5n9mA:
undetectable
1v55C-5n9mA:
undetectable
1v55N-5n9mA:
undetectable
1v55P-5n9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_A_ADNA433_2
(ADENOSYLHOMOCYSTEINA
SE)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
3 / 3 THR A  92
GLU A 176
HIS A 189
None
0.89A 1xwfA-5n9mA:
undetectable
1xwfA-5n9mA:
11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_1
(POL POLYPROTEIN)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
5 / 9 LEU A 203
ILE A 135
GLY A 177
ILE A 178
ILE A 199
None
1.05A 2avoA-5n9mA:
undetectable
2avoA-5n9mA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HW2_A_RFPA1200_1
(RIFAMPIN ADP-RIBOSYL
TRANSFERASE)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
5 / 12 GLY A  21
ASN A 196
GLY A  90
LEU A  91
LEU A 184
None
0.92A 2hw2A-5n9mA:
undetectable
2hw2A-5n9mA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_2
(ESTROGEN RECEPTOR)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
4 / 4 LEU A  91
THR A  92
ILE A  20
HIS A   8
None
1.37A 2jfaB-5n9mA:
undetectable
2jfaB-5n9mA:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_B_1UNB900_1
(PROTEASE)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
5 / 9 LEU A 203
ILE A 135
GLY A 177
ILE A 178
ILE A 199
None
1.09A 2r5qA-5n9mA:
undetectable
2r5qA-5n9mA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2R5Q_D_1UND900_1
(PROTEASE)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
5 / 9 LEU A 203
ILE A 135
GLY A 177
ILE A 178
ILE A 199
None
1.09A 2r5qC-5n9mA:
undetectable
2r5qC-5n9mA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_A_ASDA1224_1
(GLUTATHIONE
S-TRANSFERASE A3)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
4 / 7 PRO A  89
ALA A 207
LEU A 203
PHE A  57
None
0.75A 2vcvA-5n9mA:
undetectable
2vcvA-5n9mA:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
4 / 8 LEU A  14
ASP A  19
TYR A  17
HIS A 155
None
1.10A 2y69C-5n9mA:
undetectable
2y69N-5n9mA:
undetectable
2y69P-5n9mA:
undetectable
2y69C-5n9mA:
undetectable
2y69N-5n9mA:
undetectable
2y69P-5n9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
4 / 8 ASP A  19
TYR A  17
HIS A 155
LEU A  14
None
1.07A 3abmA-5n9mA:
undetectable
3abmC-5n9mA:
undetectable
3abmP-5n9mA:
undetectable
3abmA-5n9mA:
undetectable
3abmC-5n9mA:
undetectable
3abmP-5n9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
4 / 8 ASP A  19
TYR A  17
HIS A 155
LEU A  14
None
1.02A 3asoA-5n9mA:
undetectable
3asoC-5n9mA:
undetectable
3asoP-5n9mA:
undetectable
3asoA-5n9mA:
undetectable
3asoC-5n9mA:
undetectable
3asoP-5n9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW1_A_STIA233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
5 / 10 PHE A 120
GLY A 177
THR A 186
TYR A  97
ILE A 135
None
1.09A 3fw1A-5n9mA:
3.8
3fw1A-5n9mA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW1_A_STIA233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
5 / 10 PHE A 120
GLY A 177
THR A 186
TYR A  97
ILE A 143
None
1.32A 3fw1A-5n9mA:
3.8
3fw1A-5n9mA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW1_A_STIA233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
5 / 10 PHE A 120
GLY A 185
THR A 186
TYR A  97
ILE A 199
None
1.42A 3fw1A-5n9mA:
3.8
3fw1A-5n9mA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
3 / 3 THR A 142
VAL A 144
GLU A 198
None
0.68A 3v4tA-5n9mA:
undetectable
3v4tD-5n9mA:
undetectable
3v4tA-5n9mA:
undetectable
3v4tD-5n9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
4 / 8 ASP A  19
TYR A  17
HIS A 155
LEU A  14
None
1.12A 3wg7A-5n9mA:
undetectable
3wg7C-5n9mA:
undetectable
3wg7P-5n9mA:
undetectable
3wg7A-5n9mA:
undetectable
3wg7C-5n9mA:
undetectable
3wg7P-5n9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
4 / 8 ASP A  19
TYR A  17
HIS A 155
LEU A  14
None
1.14A 3x2qA-5n9mA:
undetectable
3x2qC-5n9mA:
undetectable
3x2qP-5n9mA:
undetectable
3x2qA-5n9mA:
undetectable
3x2qC-5n9mA:
undetectable
3x2qP-5n9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_A_CAMA424_0
(CYTOCHROME P450)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
5 / 9 THR A  70
THR A  92
LEU A 115
LEU A 100
GLY A 101
None
1.40A 4c9kA-5n9mA:
undetectable
4c9kA-5n9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_A_CAMA423_0
(CYTOCHROME P450)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
5 / 9 THR A  70
THR A  92
LEU A 115
LEU A 100
GLY A 101
None
1.40A 4c9pA-5n9mA:
undetectable
4c9pA-5n9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_B_ML1B303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
5 / 11 GLY A  95
GLY A  96
ILE A  93
GLY A 151
PHE A 120
None
1.17A 4qoiA-5n9mA:
3.9
4qoiB-5n9mA:
3.9
4qoiA-5n9mA:
15.93
4qoiB-5n9mA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R20_B_AERB602_1
(CYTOCHROME P450
FAMILY 17
POLYPEPTIDE 2)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
5 / 9 ALA A  83
PHE A  50
ILE A   6
GLY A  90
THR A  92
None
1.29A 4r20B-5n9mA:
undetectable
4r20B-5n9mA:
10.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
4 / 8 ASP A  19
TYR A  17
HIS A 155
LEU A  14
None
1.08A 5b1aA-5n9mA:
undetectable
5b1aC-5n9mA:
undetectable
5b1aP-5n9mA:
undetectable
5b1aA-5n9mA:
undetectable
5b1aC-5n9mA:
undetectable
5b1aP-5n9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
4 / 8 ASP A  19
TYR A  17
HIS A 155
LEU A  14
None
1.05A 5b1bA-5n9mA:
undetectable
5b1bC-5n9mA:
undetectable
5b1bP-5n9mA:
undetectable
5b1bA-5n9mA:
undetectable
5b1bC-5n9mA:
undetectable
5b1bP-5n9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
4 / 8 ASP A  19
TYR A  17
HIS A 155
LEU A  14
None
1.08A 5b3sA-5n9mA:
undetectable
5b3sC-5n9mA:
undetectable
5b3sP-5n9mA:
undetectable
5b3sA-5n9mA:
undetectable
5b3sC-5n9mA:
undetectable
5b3sP-5n9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_N_EVPN2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
4 / 6 SER A 124
GLU A 123
GLY A  60
GLY A  96
None
0.87A 5cdnR-5n9mA:
undetectable
5cdnS-5n9mA:
undetectable
5cdnR-5n9mA:
10.57
5cdnS-5n9mA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_C_ROCC101_2
(PROTEASE PR5-SQV)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
5 / 9 LEU A 203
ILE A 135
GLY A 177
ILE A 178
ILE A 199
None
1.11A 5kr2D-5n9mA:
undetectable
5kr2D-5n9mA:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
4 / 8 ASP A  19
TYR A  17
HIS A 155
LEU A  14
None
1.12A 5wauA-5n9mA:
undetectable
5wauC-5n9mA:
undetectable
5wauc-5n9mA:
undetectable
5wauA-5n9mA:
undetectable
5wauC-5n9mA:
undetectable
5wauc-5n9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
4 / 7 LEU A  14
ASP A  19
TYR A  17
HIS A 155
None
1.16A 5wauC-5n9mA:
undetectable
5waua-5n9mA:
undetectable
5wauc-5n9mA:
undetectable
5wauC-5n9mA:
undetectable
5waua-5n9mA:
undetectable
5wauc-5n9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
4 / 7 ASP A  19
TYR A  17
HIS A 155
LEU A  14
None
1.18A 5x1bA-5n9mA:
undetectable
5x1bC-5n9mA:
undetectable
5x1bP-5n9mA:
undetectable
5x1bA-5n9mA:
undetectable
5x1bC-5n9mA:
undetectable
5x1bP-5n9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
4 / 8 ASP A  19
TYR A  17
HIS A 155
LEU A  14
None
1.14A 5xdqA-5n9mA:
undetectable
5xdqC-5n9mA:
undetectable
5xdqP-5n9mA:
undetectable
5xdqA-5n9mA:
undetectable
5xdqC-5n9mA:
undetectable
5xdqP-5n9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
4 / 8 LEU A  14
ASP A  19
TYR A  17
HIS A 155
None
1.10A 5xdqC-5n9mA:
undetectable
5xdqN-5n9mA:
undetectable
5xdqP-5n9mA:
undetectable
5xdqC-5n9mA:
undetectable
5xdqN-5n9mA:
undetectable
5xdqP-5n9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
4 / 7 LEU A  14
ASP A  19
TYR A  17
HIS A 155
None
1.11A 5z84C-5n9mA:
undetectable
5z84N-5n9mA:
undetectable
5z84P-5n9mA:
undetectable
5z84C-5n9mA:
undetectable
5z84N-5n9mA:
undetectable
5z84P-5n9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
4 / 8 ASP A  19
TYR A  17
HIS A 155
LEU A  14
None
1.11A 5z85A-5n9mA:
undetectable
5z85C-5n9mA:
undetectable
5z85P-5n9mA:
undetectable
5z85A-5n9mA:
undetectable
5z85C-5n9mA:
undetectable
5z85P-5n9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
4 / 8 ASP A  19
TYR A  17
HIS A 155
LEU A  14
None
1.12A 5z86A-5n9mA:
undetectable
5z86C-5n9mA:
undetectable
5z86P-5n9mA:
undetectable
5z86A-5n9mA:
undetectable
5z86C-5n9mA:
undetectable
5z86P-5n9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
4 / 8 LEU A  14
ASP A  19
TYR A  17
HIS A 155
None
1.10A 5z86C-5n9mA:
undetectable
5z86N-5n9mA:
undetectable
5z86P-5n9mA:
undetectable
5z86C-5n9mA:
undetectable
5z86N-5n9mA:
undetectable
5z86P-5n9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
4 / 8 ASP A  19
TYR A  17
HIS A 155
LEU A  14
None
1.12A 5zcoA-5n9mA:
undetectable
5zcoC-5n9mA:
undetectable
5zcoP-5n9mA:
undetectable
5zcoA-5n9mA:
undetectable
5zcoC-5n9mA:
undetectable
5zcoP-5n9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
4 / 8 LEU A  14
ASP A  19
TYR A  17
HIS A 155
None
1.09A 5zcoC-5n9mA:
undetectable
5zcoN-5n9mA:
undetectable
5zcoP-5n9mA:
undetectable
5zcoC-5n9mA:
undetectable
5zcoN-5n9mA:
undetectable
5zcoP-5n9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
4 / 8 ASP A  19
TYR A  17
HIS A 155
LEU A  14
None
1.15A 5zcpA-5n9mA:
undetectable
5zcpC-5n9mA:
undetectable
5zcpP-5n9mA:
undetectable
5zcpA-5n9mA:
undetectable
5zcpC-5n9mA:
undetectable
5zcpP-5n9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
4 / 8 LEU A  14
ASP A  19
TYR A  17
HIS A 155
None
1.14A 5zcpC-5n9mA:
undetectable
5zcpN-5n9mA:
undetectable
5zcpP-5n9mA:
undetectable
5zcpC-5n9mA:
undetectable
5zcpN-5n9mA:
undetectable
5zcpP-5n9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
4 / 8 ASP A  19
TYR A  17
HIS A 155
LEU A  14
None
1.12A 5zcqA-5n9mA:
undetectable
5zcqC-5n9mA:
undetectable
5zcqP-5n9mA:
undetectable
5zcqA-5n9mA:
undetectable
5zcqC-5n9mA:
undetectable
5zcqP-5n9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)
5n9m COBYRIC ACID
SYNTHASE

(Staphylococcus
aureus)
4 / 7 ASP A  19
TYR A  17
HIS A 155
LEU A  14
None
1.22A 6nmfA-5n9mA:
undetectable
6nmfC-5n9mA:
undetectable
6nmfP-5n9mA:
undetectable
6nmfA-5n9mA:
undetectable
6nmfC-5n9mA:
undetectable
6nmfP-5n9mA:
undetectable