SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5n9y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_A_SALA710_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 5n9y ZINC TRANSPORT
PROTEIN ZNTB
(Escherichia
coli) 		4 / 7 VAL A   9
LEU A  20
ALA A  17
LEU A  29
 None
 0.75A 1pthA-5n9yA:
undetectable		 1pthA-5n9yA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_B_SALB711_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 5n9y ZINC TRANSPORT
PROTEIN ZNTB
(Escherichia
coli) 		4 / 7 VAL A   9
LEU A  20
ALA A  17
LEU A  29
 None
 0.75A 1pthB-5n9yA:
undetectable		 1pthB-5n9yA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_C_NCAC439_0
(ADP-RIBOSYL CYCLASE)		 5n9y ZINC TRANSPORT
PROTEIN ZNTB
(Escherichia
coli) 		3 / 3 TRP A  42
PHE A  16
TRP A  18
 None
 1.33A 1r15C-5n9yA:
undetectable		 1r15C-5n9yA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_F_NCAF469_0
(ADP-RIBOSYL CYCLASE)		 5n9y ZINC TRANSPORT
PROTEIN ZNTB
(Escherichia
coli) 		3 / 3 TRP A  42
PHE A  16
TRP A  18
 None
 1.32A 1r15F-5n9yA:
undetectable		 1r15F-5n9yA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_G_NCAG479_0
(ADP-RIBOSYL CYCLASE)		 5n9y ZINC TRANSPORT
PROTEIN ZNTB
(Escherichia
coli) 		3 / 3 TRP A  42
PHE A  16
TRP A  18
 None
 1.32A 1r15G-5n9yA:
undetectable		 1r15G-5n9yA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R15_H_NCAH489_0
(ADP-RIBOSYL CYCLASE)		 5n9y ZINC TRANSPORT
PROTEIN ZNTB
(Escherichia
coli) 		3 / 3 TRP A  42
PHE A  16
TRP A  18
 None
 1.31A 1r15H-5n9yA:
undetectable		 1r15H-5n9yA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5n9y ZINC TRANSPORT
PROTEIN ZNTB
(Escherichia
coli) 		5 / 12 ILE A 230
THR A 155
GLY A 235
GLY A 237
TYR A 208
 None
 1.02A 1rjdA-5n9yA:
undetectable		 1rjdA-5n9yA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5n9y ZINC TRANSPORT
PROTEIN ZNTB
(Escherichia
coli) 		5 / 12 ILE A 230
THR A 155
GLY A 235
GLY A 237
TYR A 208
 None
 0.98A 1rjdB-5n9yA:
undetectable		 1rjdB-5n9yA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_0
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5n9y ZINC TRANSPORT
PROTEIN ZNTB
(Escherichia
coli) 		5 / 12 ILE A 230
THR A 155
GLY A 235
GLY A 237
TYR A 208
 None
 1.00A 1rjdC-5n9yA:
undetectable		 1rjdC-5n9yA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_H_SAMH226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5n9y ZINC TRANSPORT
PROTEIN ZNTB
(Escherichia
coli) 		5 / 12 LEU A 134
VAL A  11
GLY A   6
LEU A 115
ILE A  35
 None
 1.01A 3ku1H-5n9yA:
undetectable		 3ku1H-5n9yA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWZ_B_BEZB301_0
(14-3-3 PROTEIN
ZETA/DELTA)		 5n9y ZINC TRANSPORT
PROTEIN ZNTB
(Escherichia
coli) 		3 / 3 MET A 227
GLN A 223
ARG A 224
 None
 0.92A 5ewzB-5n9yA:
3.8		 5ewzB-5n9yA:
20.86